WARNING

Vibativ, or telavancin, is an antibiotic used to treat certain bacterial infections. Like any medication, Vibativ comes with potential risks and side effects. It’s crucial to note that only a healthcare professional can provide personalized information based on an individual’s medical history. Here is a brief overview of some common risks associated with Vibativ:

• Allergic Reactions: Some individuals may experience allergic reactions to Vibativ, which can range from mild to severe. Symptoms may include rash, itching, swelling, severe dizziness, or difficulty breathing. If any of these symptoms occur, seek medical attention immediately.
• Kidney Function: Vibativ has been associated with potential kidney problems. Patients with pre-existing kidney conditions may be at a higher risk. Regular monitoring of kidney function is often recommended during Vibativ treatment.
• Liver Function: Elevated liver enzymes have been reported in some patients taking Vibativ. Regular liver function tests may be necessary during treatment.
• Clostridium difficile Infection: Antibiotic use, including Vibativ, can increase the risk of Clostridium difficile infection, which causes severe diarrhea. It’s important to notify your healthcare provider if you experience persistent diarrhea during or after treatment.
• QT Prolongation: Vibativ has been associated with QT prolongation, which is an alteration in the heart’s electrical activity. This can lead to a potentially serious irregular heart rhythm. Patients with a history of heart conditions or taking other medications that can prolong the QT interval may be at a higher risk.
• Drug Interactions: Vibativ may interact with other medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare provider about all medications, supplements, and herbal products you are taking.

It’s crucial to follow your healthcare provider’s instructions, report any unusual symptoms or side effects promptly, and attend scheduled follow-up appointments to monitor for potential risks. This information is not exhaustive, and individual responses to medications can vary, so it’s essential to consult with a healthcare professional for personalized advice.

Why is this medication prescribed?

Vibativ (telavancin) is an antibiotic medication prescribed to treat certain bacterial infections. It belongs to a class of antibiotics called lipoglycopeptides and is specifically used to combat infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA).

Vibativ is typically prescribed for the following conditions:

• Skin and Skin Structure Infections (SSSIs): Vibativ may be used to treat complicated skin and skin structure infections caused by susceptible bacteria, including MRSA.
• Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia: In some cases, Vibativ is prescribed for the treatment of these types of pneumonia, especially when caused by susceptible Gram-positive bacteria.

It’s important to note that Vibativ is generally reserved for situations where other treatment options may not be suitable due to factors like resistance to other antibiotics or intolerance to alternative medications.

How should this medicine be used?

Here are some general guidelines on how Vibativ is typically used:

• Dosage: The dosage of Vibativ can vary based on the specific infection being treated, the patient’s weight, and other individual factors. It is administered intravenously (through a vein).
• Administration: Vibativ is typically given over a specific duration as determined by the prescribing healthcare provider. The infusion is usually administered once a day.
• Duration of Treatment: The duration of treatment with Vibativ varies depending on the severity and type of infection. It is important to complete the full course of the prescribed medication, even if symptoms improve before the medication is finished.
• Monitoring: During the course of treatment, healthcare providers may monitor kidney function, liver function, and other relevant parameters through laboratory tests.
• Follow Healthcare Provider’s Instructions: Patients should strictly follow the instructions provided by their healthcare provider, including the schedule for medication administration and any additional recommendations regarding diet or other medications.

As with any antibiotic, it’s crucial for patients to inform their healthcare provider about any allergies, existing medical conditions, or other medications they are taking. Additionally, if any side effects or unusual symptoms occur during the course of treatment, it’s important to promptly inform the healthcare provider.

This information is a general overview, and specific details about Vibativ use should be discussed with a healthcare professional who can provide guidance tailored to an individual’s medical situation.

Other uses for this medicine

Vibativ (telavancin) is primarily used for the treatment of certain bacterial infections, particularly skin and skin structure infections caused by susceptible Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). While it is crucial to use Vibativ as prescribed by a healthcare professional for its approved indications, it’s important to note that medications may sometimes be used off-label for conditions beyond their officially approved uses. However, any off-label use should only occur under the guidance and supervision of a healthcare provider.

What special precautions should I follow?

Special Precautions for Vibativ:

• Allergies: Individuals with known allergies or hypersensitivity to telavancin or other lipoglycopeptides should not use Vibativ.
• Kidney Function: Vibativ has been associated with potential kidney problems. Patients with pre-existing kidney conditions or those at risk for kidney impairment should be monitored closely during treatment.
• Liver Function: Elevated liver enzymes have been reported in some patients taking Vibativ. Regular liver function tests may be necessary during treatment.
• QT Prolongation: Vibativ has been associated with QT prolongation, which is an alteration in the heart’s electrical activity. Caution is advised in patients with a history of heart conditions or those taking other medications that can prolong the QT interval.
• Clostridium difficile Infection: Antibiotic use, including Vibativ, can increase the risk of Clostridium difficile infection, which causes severe diarrhea. If persistent diarrhea occurs, it should be reported to the healthcare provider.
• Pregnancy and Breastfeeding: The safety of Vibativ during pregnancy and breastfeeding is not well-established. It should be used during pregnancy only if the potential benefits justify the potential risks. It is not known whether Vibativ passes into breast milk, so breastfeeding should be avoided during treatment.
• Drug Interactions: Vibativ may interact with other medications, and concomitant use should be carefully monitored. Inform your healthcare provider about all medications, supplements, and herbal products you are taking.

It’s essential to communicate openly with your healthcare provider about your medical history, existing conditions, and any medications you are currently taking. This information helps the healthcare provider make informed decisions about the suitability of Vibativ for your specific situation and tailor the treatment plan accordingly.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Vibativ. However, it’s important to maintain a balanced and healthy diet to support your overall well-being during the course of treatment.

What should I do if I forget a dose?

If you miss a dose of Vibativ, it’s important to contact your healthcare provider or follow their instructions. The missed dose should be administered as soon as you remember, but if it’s close to the time of your next scheduled dose, you should skip the missed dose and resume your regular dosing schedule. Do not double up on doses to make up for a missed one. Always follow the guidance provided by your healthcare provider regarding missed doses, as they can offer specific advice based on your individual circumstances.

What side effects can this medication cause?

Vibativ (telavancin) can cause various side effects, and it’s important to be aware of them and promptly report any unusual symptoms to your healthcare provider. Not everyone will experience these side effects, and their severity can vary. Common side effects of Vibativ include:

• Nausea: Feeling sick to your stomach is a common side effect.
• Headache: Some people may experience headaches while taking Vibativ.
• Taste Disturbances: Altered or metallic taste in the mouth has been reported.
• Insomnia: Difficulty sleeping may occur in some individuals.
• Rash: Skin rash or itching may occur as a side effect.
• Kidney Effects: Vibativ has been associated with potential kidney problems, so monitoring kidney function is important.
• Liver Effects: Elevated liver enzymes have been reported in some patients, necessitating regular liver function tests.
• QT Prolongation: Vibativ can cause QT prolongation, affecting the heart’s electrical activity. This may lead to an irregular heart rhythm.
• Infusion Site Reactions: Pain, redness, or swelling at the site where the medication is administered intravenously.
• Clostridium difficile Infection: Antibiotic use, including Vibativ, can increase the risk of Clostridium difficile infection, leading to severe diarrhea.

It’s important to note that this is not an exhaustive list, and individual responses to medications can vary. Serious side effects are possible, and some individuals may experience an allergic reaction, difficulty breathing, or other severe symptoms.

If you experience any unusual or severe side effects while taking Vibativ, contact your healthcare provider immediately. In case of a medical emergency, seek medical attention or call emergency services.

This information is provided as a general overview, and specific details about potential side effects and their management should be discussed with your healthcare provider, who can provide guidance based on your individual health status and medical history.

What should I know about storage and disposal of this medication?

Storage and Disposal of Vibativ:

• Storage: Store Vibativ as directed by your healthcare provider or pharmacist. Typically, it is stored in a healthcare setting and administered by healthcare professionals. If you are provided with a supply for home use, follow storage instructions carefully, and keep it out of reach of children.
• Disposal: Do not keep unused Vibativ unless directed by your healthcare provider. If you have unused medication, consult with your pharmacist or healthcare provider regarding proper disposal methods. Do not flush medications down the toilet unless instructed to do so. Proper disposal helps prevent environmental contamination.

In case of emergency/overdose

In case of an emergency or suspected overdose of Vibativ, contact your local poison control center at 1-800-222-1222 or seek emergency medical attention immediately. Be prepared to provide information about the medication, the amount ingested (if known), and any symptoms experienced.

What other information should I know?

• Follow Healthcare Provider’s Instructions: Take Vibativ exactly as prescribed by your healthcare provider. Do not alter the dosage or stop taking the medication without consulting your healthcare provider.
• Regular Monitoring: Your healthcare provider may conduct regular tests to monitor your kidney function, liver function, and overall health during Vibativ treatment.
• Informing Healthcare Providers: Inform all healthcare providers involved in your care about the use of Vibativ, including dentists and surgeons. This helps ensure coordinated and safe medical care.
• Allergies: Inform your healthcare provider about any allergies or adverse reactions to medications, especially if you’ve had a reaction to telavancin or other lipoglycopeptides.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of Vibativ with your healthcare provider.
• Drug Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential drug interactions.
• Clostridium difficile Infection: Be aware of the symptoms of Clostridium difficile infection, such as persistent diarrhea, and report any concerns to your healthcare provider.

Always seek guidance from your healthcare provider for any specific information or concerns related to your individual health and the use of Vibativ. This information is a general overview and should not replace personalized advice from a healthcare professional.