Why is this medication prescribed?

Uroxatral (generic name: alfuzosin) is a medication primarily prescribed to treat symptoms of an enlarged prostate, also known as benign prostatic hyperplasia (BPH). BPH is a common condition in older men where the prostate gland, located below the bladder, enlarges and can cause urinary problems.

Uroxatral belongs to a class of medications called alpha-1 blockers. It works by relaxing the muscles in the prostate and bladder neck, making it easier for urine to pass through the urethra, and helping to relieve symptoms such as difficulty urinating, incomplete emptying of the bladder, and the need to urinate frequently or urgently.

How should this medicine be used?

Here are some general guidelines on how Uroxatral is usually used:

• Dosage: The typical recommended dose is 10 mg once daily, taken after the same meal each day. It’s important to take the medication exactly as prescribed by your healthcare provider.
• Administration: Uroxatral should be taken with food to enhance its absorption. Swallow the tablet whole, and do not crush, chew, or break it.
• Consistency: Try to take Uroxatral at the same time each day to maintain a consistent level of the medication in your body.
• Avoid certain activities: Uroxatral may cause dizziness or fainting, especially when you first start taking it. To reduce the risk of these side effects, avoid activities that require alertness, such as driving or operating machinery, until you know how the medication affects you.
• Follow-up appointments: Your healthcare provider may want to monitor your progress periodically and may adjust your dosage if needed.

Always follow your healthcare provider’s instructions and inform them of any other medications or supplements you are taking, as well as any existing medical conditions. If you have questions or concerns about Uroxatral or its usage, it’s crucial to discuss them with your healthcare provider for personalized advice.

Other uses for this medicine

Uroxatral (alfuzosin) is primarily used for the treatment of benign prostatic hyperplasia (BPH), but it may have some off-label uses as well. Off-label use refers to the use of a medication for a purpose other than what it is approved for by regulatory agencies. However, any such use should be done under the guidance and supervision of a healthcare professional. Some potential off-label uses of Uroxatral may include the treatment of chronic prostatitis or other urological conditions, but this would depend on the specific circumstances and the healthcare provider’s judgment.

What special precautions should I follow?

As for special precautions, it’s important to note the following:

• Allergies: Inform your healthcare provider if you are allergic to alfuzosin or any other medications.
• Medical history: Before taking Uroxatral, provide a comprehensive medical history, especially if you have liver disease, kidney disease, low blood pressure, or a history of prostate cancer.
• Interaction with other medications: Uroxatral may interact with other medications, particularly those that affect the heart rhythm. Inform your healthcare provider about all the medications (prescription and over-the-counter), vitamins, and supplements you are taking.
• Avoid certain activities: As mentioned earlier, Uroxatral may cause dizziness or fainting, particularly when you first start taking it. Use caution when getting up from a sitting or lying position, especially if you feel lightheaded.
• Pregnancy and breastfeeding: Uroxatral is not intended for use in women and should not be used during pregnancy or breastfeeding.
• Prostate cancer: Before starting Uroxatral, your healthcare provider may want to rule out the presence of prostate cancer. The symptoms of an enlarged prostate can overlap with those of prostate cancer.
• Eye surgery: If you are scheduled for eye surgery (such as cataract surgery), inform your eye surgeon that you are taking or have taken Uroxatral. This is because Uroxatral can affect the iris, causing intraoperative floppy iris syndrome (IFIS), which may make it more challenging for the surgeon during the procedure.

It’s crucial to follow your healthcare provider’s instructions and attend regular follow-up appointments to monitor your response to the medication and address any concerns. If you experience any unusual or severe side effects, contact your healthcare provider promptly.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Uroxatral. However, taking the medication with food, particularly a meal that contains fats, can enhance its absorption. Therefore, it is recommended to take Uroxatral with a meal.

What should I do if I forget a dose?

If you forget a dose:

• Regular Schedule: If you miss a dose of Uroxatral, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Double Dosing: Do not double the dose to make up for a missed one. Taking more than the prescribed amount can increase the risk of side effects.
• Consult your Healthcare Provider: If you are unsure about what to do or if you miss multiple doses, consult your healthcare provider for guidance.

What side effects can this medication cause?

Uroxatral (alfuzosin) may cause side effects, and it’s important to be aware of them. Not everyone will experience these side effects, and some individuals may tolerate the medication well. Common and less serious side effects may include:

• Dizziness or lightheadedness: This is a common side effect, especially when standing up from a sitting or lying position. It’s important to get up slowly to minimize the risk of dizziness.
• Headache: Some people may experience headaches while taking Uroxatral.
• Fatigue: Feeling tired or fatigued can occur as a side effect.
• Stomach discomfort: This may include symptoms such as nausea or stomach pain.
• Runny or stuffy nose: Some people may experience nasal congestion or a runny nose.

Serious side effects are rare, but they can occur. Contact your healthcare provider immediately if you experience any of the following:

• Hypotension (Low Blood Pressure): Uroxatral can cause a drop in blood pressure, leading to symptoms such as fainting, dizziness, or lightheadedness.
• Allergic reactions: Seek medical attention if you develop symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.
• Priapism: This is a prolonged and painful erection. Although rare, priapism requires immediate medical attention.
• Jaundice: If you notice yellowing of the eyes or skin (jaundice), it could be a sign of a liver problem.

It’s important to note that this is not a comprehensive list of side effects. Always consult with your healthcare provider for personalized information about potential side effects, especially if you have pre-existing medical conditions or are taking other medications. If you experience any severe or persistent side effects, contact your healthcare provider promptly. They can provide guidance on whether adjustments to your treatment plan are needed.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage: Store Uroxatral at room temperature, away from light and moisture. Keep it out of reach of children.
• Disposal: Dispose of unused or expired medication properly. Do not flush it down the toilet unless instructed to do so. Consult your healthcare provider or local pharmacy for information on how to dispose of medications in an environmentally friendly and safe manner.

In case of emergency/overdose

In case of an overdose or emergency, contact your local poison control center at 1-800-222-1222 or go to the nearest emergency room immediately. Symptoms of an overdose may include extreme dizziness, fainting, or severe weakness.

What other information should I know?

• Regular Follow-up: Attend regular follow-up appointments with your healthcare provider to monitor your response to Uroxatral and address any concerns.
• Inform Healthcare Providers: Make sure all healthcare providers (including dentists and emergency medical personnel) are aware that you are taking Uroxatral. Mention it before any surgeries or medical procedures.
• Avoid Grapefruit Juice: Grapefruit juice can interact with Uroxatral and should be avoided.
• Alcohol Interaction: Limit alcohol consumption while taking Uroxatral, as alcohol can enhance the side effects of the medication.
• Inform About Other Medications: Inform your healthcare provider about all medications, vitamins, and supplements you are taking, as Uroxatral can interact with other drugs.
• Pregnancy and Breastfeeding: Uroxatral is not intended for use in women, and its safety during pregnancy or breastfeeding has not been established.
• Driving and Operating Machinery: Uroxatral may cause dizziness or fainting, especially at the beginning of treatment. Use caution when driving or operating machinery until you know how the medication affects you.

Always follow the instructions provided by your healthcare provider and the medication’s packaging. If you have any questions or concerns, do not hesitate to discuss them with your healthcare provider for personalized advice.