Why is this medication prescribed?

Unasyn is a combination antibiotic medication that is prescribed to treat bacterial infections. It contains two active ingredients: ampicillin and sulbactam. The combination is effective against a variety of bacteria, and its use is typically reserved for infections caused by organisms that may be resistant to standard antibiotics. Here are some common reasons why Unasyn might be prescribed:

• Bacterial Infections: Unasyn is often used to treat various types of bacterial infections, including respiratory tract infections, skin and soft tissue infections, urinary tract infections, intra-abdominal infections, and gynecological infections.
• Mixed Infections: In cases where the infection involves a mix of bacteria, including some that may produce beta-lactamase (an enzyme that can inactivate certain antibiotics), the addition of sulbactam helps to enhance the effectiveness of ampicillin by inhibiting the beta-lactamase enzymes.
• Hospital-Acquired Infections: Unasyn may be used for treating infections acquired in a hospital setting, where there is a higher likelihood of encountering bacteria that are resistant to standard antibiotics.

How should this medicine be used?

The usage of Unasyn (ampicillin-sulbactam) should be strictly according to your healthcare provider’s prescription. Dosage and administration may vary based on the type and severity of the infection, the specific bacteria involved, and individual patient factors. Always follow your healthcare provider’s instructions and read the medication guide provided by the pharmacist. Here are general guidelines for the use of Unasyn:

• Dosage: The dosage of Unasyn is determined by your healthcare provider based on factors such as the type and severity of the infection, your age, weight, and overall health. The dosage may be given intravenously (IV) or intramuscularly (IM) in a healthcare setting, or in some cases, it may be prescribed as oral tablets.
• Administration: If Unasyn is administered intravenously or intramuscularly, it will be given by a healthcare professional in a hospital or clinic setting. The healthcare provider will follow proper procedures for administration.
• Oral Administration: If Unasyn is prescribed in oral form, it is usually taken with a full glass of water, either with or without food. Follow the prescribed dosage and schedule precisely.
• Completion of Course: It’s important to complete the entire course of Unasyn, even if you start feeling better before the medication is finished. Stopping antibiotics prematurely can lead to incomplete eradication of the infection and may contribute to antibiotic resistance.
• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses to make up for a missed one.
• Storage: Store Unasyn at room temperature, away from moisture and heat. Follow any specific storage instructions provided by your pharmacist.
• Consultation: Keep your healthcare provider informed about any side effects or changes in your condition. If you have concerns or questions about your medication, consult your healthcare provider or pharmacist.

It’s crucial to use Unasyn exactly as prescribed and to communicate with your healthcare provider throughout the course of treatment. If you have any questions or concerns about the medication, don’t hesitate to discuss them with your healthcare provider.

Other uses for this medicine

While Unasyn is primarily indicated for bacterial infections, its use may extend to various specific conditions, including:

• Skin and Soft Tissue Infections: Unasyn is often prescribed for skin and soft tissue infections caused by susceptible bacteria.
• Intra-abdominal Infections: It may be used for intra-abdominal infections, such as peritonitis, when caused by susceptible bacteria.
• Respiratory Tract Infections: Unasyn can be employed in the treatment of respiratory tract infections, particularly lower respiratory tract infections.
• Urinary Tract Infections: In certain cases, Unasyn may be used to treat urinary tract infections caused by susceptible bacteria.

What special precautions should I follow?

It’s essential to take certain precautions while using Unasyn. These precautions help ensure the effectiveness of the medication and minimize potential side effects. Here are some special precautions to consider:

• Allergies: Inform your healthcare provider of any allergies to antibiotics, especially penicillins, cephalosporins, or other substances.
• Medical History: Provide a complete medical history to your healthcare provider, including any history of kidney problems, gastrointestinal issues, or other conditions that may impact the use of Unasyn.
• Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The decision to use Unasyn during pregnancy or breastfeeding will depend on the potential benefits and risks, and your healthcare provider will guide you accordingly.
• Interactions with Other Medications: Inform your healthcare provider of all medications, supplements, or herbal products you are taking, as Unasyn may interact with certain drugs.
• Monitoring: Your healthcare provider may monitor your liver and kidney function, especially if you are on a prolonged course of Unasyn.
• Complete the Course: Finish the entire course of Unasyn as prescribed by your healthcare provider, even if symptoms improve before completion. Stopping antibiotics prematurely may lead to incomplete eradication of the infection and the development of antibiotic resistance.

Always follow the specific guidance provided by your healthcare provider. If you have any concerns or questions about Unasyn or its use, discuss them with your healthcare professional.

What special dietary instructions should I follow?

There are generally no specific dietary restrictions associated with Unasyn. However, it’s essential to follow any instructions provided by your healthcare provider or pharmacist. In some cases, Unasyn may be taken with or without food, depending on the specific formulation. If your healthcare provider provides specific dietary instructions, be sure to follow them.

What should I do if I forget a dose?

If you forget to take a dose of Unasyn, follow these general guidelines:

• Oral Formulation (Tablets):
  • Take the missed dose as soon as you remember.
  • If it’s almost time for your next dose, skip the missed dose.
  • Do not double up on doses to make up for a missed one.
• Intravenous (IV) Administration:
  • If you miss a scheduled IV dose administered by a healthcare professional, inform them as soon as possible.

What side effects can this medication cause?

Unasyn is a combination antibiotic medication that contains ampicillin and sulbactam. It is used to treat various bacterial infections. Like any medication, Unasyn can cause side effects. It’s important to note that not everyone will experience these side effects, and some people may experience different side effects to varying degrees of severity. Common side effects of Unasyn may include:

• Gastrointestinal Effects:
  • Nausea
  • Vomiting
  • Diarrhea
• Allergic Reactions:
  • Rash
  • Itching
  • Swelling
• Hematologic Effects:
  • Thrombocytosis (increased platelet count)
  • Eosinophilia (increased eosinophils)
• Liver Function Abnormalities:
  • Elevated liver enzymes
• Central Nervous System Effects:
  • Headache
  • Dizziness
• Local Effects:
  • Pain or inflammation at the injection site for intravenous administration

It’s essential to inform your healthcare provider if you experience any side effects while taking Unasyn. Serious side effects are rare but may include severe allergic reactions (anaphylaxis) or Clostridium difficile-associated diarrhea, which can be a result of disrupting the balance of normal bacteria in the colon.

This is not an exhaustive list of side effects, and individual responses to medications can vary. Always follow your healthcare provider’s instructions and report any unusual or severe symptoms promptly. If you have concerns about the side effects of Unasyn or any other medication, it’s important to discuss them with your healthcare provider. They can provide personalized information based on your health history and current medical condition.

What should I know about storage and disposal of this medication?

Storage and Disposal of Unasyn:

• Storage:
  • Store Unasyn at room temperature, away from excess heat and moisture.
  • Keep the medication out of the reach of children and pets.
  • Follow any specific storage instructions provided by your healthcare provider or pharmacist.
• Disposal:
  • Dispose of unused or expired Unasyn properly.
  • Do not flush medications down the toilet or pour them into drains unless instructed to do so.
  • Consult with your pharmacist or local waste disposal facility for guidance on the proper disposal of medications.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms, seek emergency medical attention or contact your local poison control center immediately. Symptoms of overdose may include:

• Seizures
• Severe diarrhea
• Unconsciousness

What other information should I know?

• Follow Instructions: Take Unasyn exactly as prescribed by your healthcare provider. Do not adjust the dosage without consulting your healthcare professional.
• Complete the Course: Finish the entire prescribed course of Unasyn, even if symptoms improve before the medication is finished. This helps prevent the development of antibiotic resistance.
• Inform Healthcare Provider: Inform your healthcare provider about any other medications, supplements, or herbal products you are taking. Notify your healthcare provider of any known allergies to antibiotics, especially penicillins or cephalosporins.
• Regular Monitoring: Your healthcare provider may monitor your progress during the course of Unasyn treatment. Attend follow-up appointments as scheduled.
• Avoid Alcohol: While there is no specific contraindication with moderate alcohol consumption, it’s generally advisable to limit alcohol intake during antibiotic treatment.
• Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Your healthcare provider will weigh the benefits and risks and provide guidance accordingly.
• Notify Healthcare Provider of Side Effects: If you experience any unexpected or severe side effects, contact your healthcare provider promptly.
• Allergic Reactions: Be vigilant for signs of allergic reactions, such as rash, itching, or difficulty breathing. Seek medical attention if these symptoms occur.

Always consult with your healthcare provider or pharmacist for personalized advice based on your specific health condition and the prescribed treatment plan. If you have any questions or concerns about Unasyn, discuss them with your healthcare professional.