Why is this medication prescribed?

Ubrelvy (ubrogepant) is a medication that is prescribed for the acute treatment of migraine with or without aura in adults. It belongs to a class of drugs known as calcitonin gene-related peptide (CGRP) receptor antagonists.

Migraine is a neurological disorder characterized by recurrent moderate to severe headaches, often accompanied by other symptoms such as nausea, vomiting, and sensitivity to light and sound. The exact cause of migraines is not fully understood, but CGRP is believed to play a role in the dilation of blood vessels in the brain, which is thought to contribute to the pain associated with migraines.

Ubrelvy works by blocking the action of CGRP, thereby reducing the dilation of blood vessels and alleviating migraine symptoms. It is not intended for preventive treatment but is used to treat migraines when they occur.

How should this medicine be used?

Ubrelvy (ubrogepant) is typically available in tablet form, and it is taken orally. The recommended dosage and usage instructions may vary based on individual factors, so it’s important to follow the specific guidance provided by your healthcare provider. However, here are some general guidelines for the use of Ubrelvy:

• Dosage: The typical recommended dose for Ubrelvy is a single tablet (50 mg or 100 mg) taken as needed for the acute treatment of migraine.
• Timing of Administration: It is generally advised to take Ubrelvy as soon as possible after the onset of a migraine headache. It can be taken with or without food.
• Frequency of Use: The medication is intended for use on an as-needed basis and should not be taken more than once in a 24-hour period. If the migraine symptoms persist or recur after the initial dose, patients should consult their healthcare provider before taking another dose.
• Avoiding Overuse: It’s important to avoid using Ubrelvy excessively, as overuse of acute migraine medications can lead to medication-overuse headaches. If you find that you need to take Ubrelvy more frequently than prescribed, consult your healthcare provider.
• Special Considerations: Inform your healthcare provider about any other medications, supplements, or medical conditions you may have, as certain drugs or conditions may interact with Ubrelvy.
• Monitoring for Side Effects: Pay attention to any potential side effects, and contact your healthcare provider if you experience any adverse reactions.

Always follow your healthcare provider’s instructions and read the medication guide provided with Ubrelvy for specific information. If you have any questions or concerns about the use of Ubrelvy, do not hesitate to discuss them with your healthcare provider.

Other uses for this medicine

Ubrelvy (ubrogepant) is specifically approved for the acute treatment of migraine with or without aura in adults, and its use for other purposes has not been established. It is not intended for routine use or as a preventive treatment for migraines. It’s important to use Ubrelvy only under the guidance and prescription of a healthcare professional.

What special precautions should I follow?

Special precautions and considerations for using Ubrelvy include:

• Medical History: Before prescribing Ubrelvy, your healthcare provider should be informed about your complete medical history, including any allergies, pre-existing medical conditions, and a history of liver problems.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Ubrelvy with your healthcare provider. The safety of Ubrelvy during pregnancy and breastfeeding is not well established.
• Liver Impairment: Ubrelvy is metabolized in the liver, and individuals with moderate or severe hepatic impairment may require dosage adjustments. Your healthcare provider will consider your liver function before prescribing this medication.
• Drug Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as Ubrelvy may interact with certain drugs. This includes medications that are strong inhibitors or inducers of the enzyme CYP3A4, as well as medications that are substrates of P-gp (P-glycoprotein).
• Alcohol: There are no specific restrictions on alcohol use with Ubrelvy. However, it’s advisable to discuss alcohol consumption with your healthcare provider, as excessive alcohol intake can trigger or exacerbate migraines in some individuals.
• Driving and Operating Machinery: Ubrelvy can cause dizziness, so caution should be exercised when driving or operating machinery until the individual’s response to the medication is known.

Always follow your healthcare provider’s instructions and communicate any concerns or side effects promptly. If you have questions about the use of Ubrelvy or if it’s suitable for your specific situation, consult with your healthcare provider for personalized advice.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are no specific dietary restrictions associated with Ubrelvy. However, it’s always a good idea to maintain a healthy and balanced diet, as lifestyle factors, including diet, can influence migraine frequency and severity.

What should I do if I forget a dose?

If you forget a dose of Ubrelvy, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one. If you are unsure about what to do, consult with your healthcare provider for guidance.

What side effects can this medication cause?

Ubrelvy (ubrogepant) may cause side effects, and it’s important to be aware of them. Common side effects may include:

• Nausea: Some individuals may experience nausea as a side effect of Ubrelvy.
• Fatigue: Feeling tired or fatigued can occur in some people using this medication.
• Dry Mouth: Dry mouth may occur as a side effect.
• Dizziness: Ubrelvy can cause dizziness. It’s important to avoid activities that require alertness, such as driving or operating machinery, until you know how the medication affects you.
• Increased Liver Enzymes: In some cases, Ubrelvy may cause an increase in liver enzymes. Your healthcare provider may monitor your liver function during treatment.

It’s important to note that not everyone will experience these side effects, and some individuals may not experience any side effects at all. Additionally, serious allergic reactions are rare but possible. Seek medical attention immediately if you experience symptoms of a serious allergic reaction, such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing.

This is not an exhaustive list of side effects, and individual responses to medication can vary. If you have concerns about potential side effects or experience any unusual symptoms while taking Ubrelvy, contact your healthcare provider promptly. They can provide guidance based on your specific health status and determine the most appropriate course of action.

What should I know about storage and disposal of this medication?

Storage and Disposal of Ubrelvy:

• Storage:
  • Temperature: Store Ubrelvy at room temperature, away from excessive heat or moisture.
  • Container: Keep the medication in its original container, and make sure the container is tightly closed.
  • Out of Reach: Store Ubrelvy out of reach of children and pets.
• Disposal:
  • Follow Instructions: Dispose of unused or expired medications according to local regulations and guidelines. Do not flush medications down the toilet unless instructed to do so.
  • Take-Back Programs: Check if there are any medication take-back programs in your community where you can safely dispose of medications.
  • Ask Your Pharmacist: Your pharmacist can provide guidance on proper disposal methods.

In case of emergency/overdose

In case of an emergency or suspected overdose:

• Seek Medical Attention: Call your local emergency number (e.g., 911 in the United States) or go to the nearest emergency room.
• Symptoms of Overdose: Symptoms of overdose may include severe dizziness, fainting, or difficulty breathing.

What other information should I know?

• Regular Check-ups: Attend regular check-ups with your healthcare provider to monitor the effectiveness of the medication and discuss any concerns or changes in your health.
• Inform Healthcare Providers: Inform all healthcare providers involved in your care, including dentists and surgeons, that you are taking Ubrelvy. This helps them make informed decisions about your treatment.
• Keep a Medication List: Maintain an updated list of all medications, including over-the-counter drugs, supplements, and herbal products, and share it with your healthcare provider.
• Adhere to Instructions: Take Ubrelvy exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage or use it more frequently than advised.
• Report Side Effects: If you experience any unusual or severe side effects, contact your healthcare provider promptly.

Always consult with your healthcare provider or pharmacist if you have specific questions about the storage, disposal, or emergency procedures related to Ubrelvy. They can provide personalized advice based on your health status and individual circumstances.