WARNING

Tyzeka (telbivudine) is a prescription medication primarily used to treat chronic hepatitis B virus infection. Like all medications, Tyzeka carries certain risks and side effects. Some potential risks of taking Tyzeka include:

• Drug Resistance: Over time, the hepatitis B virus may develop resistance to Tyzeka, reducing its effectiveness in treating the infection.
• Liver Problems: Tyzeka can sometimes cause liver problems, including hepatomegaly (enlarged liver), hepatic steatosis (fatty liver), and in rare cases, severe liver damage.
• Exacerbation of Hepatitis B: In some cases, stopping Tyzeka treatment can lead to a sudden flare-up of hepatitis B infection. This can cause symptoms such as jaundice, abdominal pain, and fatigue.
• Muscle Weakness and Pain: Some individuals taking Tyzeka may experience muscle weakness, pain, or tenderness. In rare cases, this can progress to more severe muscle disorders such as myopathy or rhabdomyolysis.
• Peripheral Neuropathy: Tyzeka may cause peripheral neuropathy, a condition characterized by numbness, tingling, or weakness in the hands and feet.
• Pancreatitis: There have been reports of pancreatitis (inflammation of the pancreas) in individuals taking Tyzeka. Symptoms may include severe abdominal pain, nausea, and vomiting.
• Lactic Acidosis: Rarely, Tyzeka can lead to a buildup of lactic acid in the blood, a condition known as lactic acidosis. Symptoms may include weakness, rapid breathing, nausea, vomiting, and abdominal pain.
• Immune Reactions: Some individuals may experience allergic reactions to Tyzeka, which can manifest as rash, itching, swelling, dizziness, or difficulty breathing.

It’s essential for individuals taking Tyzeka to be monitored closely by their healthcare provider for any signs of adverse reactions or complications. Additionally, patients should inform their doctor of any other medications they are taking, as Tyzeka can interact with certain drugs, potentially increasing the risk of side effects.

Why is this medication prescribed?

Tyzeka (telbivudine) is prescribed primarily for the treatment of chronic hepatitis B virus (HBV) infection in adults. Hepatitis B is a viral infection that affects the liver, causing inflammation and potentially leading to liver damage, cirrhosis, or liver cancer over time. Tyzeka works by inhibiting the replication of the hepatitis B virus, thereby helping to reduce viral load and slow down the progression of the disease.

How should this medicine be used?

Dosage and administration of Tyzeka:

• Dosage: The typical recommended dose of Tyzeka for adults with chronic hepatitis B is 600 mg taken orally once daily.
• Administration: Tyzeka tablets should be taken with a full glass of water, with or without food. It’s important to take Tyzeka exactly as prescribed by your healthcare provider and not to alter the dosage or stop taking the medication without consulting your doctor.
• Monitoring: While taking Tyzeka, your doctor will likely perform regular tests to monitor your liver function and hepatitis B viral load. These tests help assess the effectiveness of the treatment and detect any potential side effects or complications.
• Duration of Treatment: The duration of Tyzeka treatment can vary depending on individual response to the medication and the severity of hepatitis B infection. Some patients may need to take Tyzeka long-term to maintain viral suppression and prevent disease progression.
• Missed Dose: If you miss a dose of Tyzeka, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

It’s crucial to follow your healthcare provider’s instructions carefully when taking Tyzeka to achieve the best treatment outcomes and minimize the risk of complications. Additionally, inform your doctor about any other medications, supplements, or medical conditions you have, as they may affect the safety and effectiveness of Tyzeka treatment.

Other uses for this medicine

Tyzeka (telbivudine) is primarily prescribed for the treatment of chronic hepatitis B virus (HBV) infection in adults and is not typically used for other conditions. However, it’s essential to follow your healthcare provider’s recommendations regarding the use of Tyzeka and not to use it for any other purpose unless specifically instructed by your doctor.

What special precautions should I follow?

Special precautions to consider when taking Tyzeka:

• Pregnancy and Breastfeeding: Tyzeka may cause harm to an unborn baby, so it’s important to inform your doctor if you are pregnant or planning to become pregnant. Additionally, it’s not known whether Tyzeka passes into breast milk, so breastfeeding while taking Tyzeka is not recommended.
• Liver Function: Before starting Tyzeka treatment, your doctor will likely perform tests to assess your liver function. Tyzeka can cause liver problems, so it’s essential to monitor liver function regularly during treatment.
• Muscle and Nerve Problems: Tyzeka may cause muscle weakness, pain, or numbness, as well as peripheral neuropathy (nerve damage). If you experience any unusual muscle symptoms or signs of nerve problems, such as tingling or weakness in the hands and feet, inform your doctor immediately.
• Lactic Acidosis: Rarely, Tyzeka can lead to a buildup of lactic acid in the blood, a condition known as lactic acidosis. This is more likely to occur in people with liver problems or those taking certain medications. Inform your doctor if you experience symptoms such as weakness, rapid breathing, nausea, vomiting, or abdominal pain.
• Drug Interactions: Tyzeka may interact with other medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your doctor about all medications, supplements, or herbal products you are taking before starting Tyzeka treatment.
• Allergic Reactions: Some individuals may experience allergic reactions to Tyzeka, which can manifest as rash, itching, swelling, dizziness, or difficulty breathing. If you experience any signs of an allergic reaction, seek medical attention immediately.
• Regular Monitoring: It’s important to attend regular follow-up appointments with your healthcare provider while taking Tyzeka. Your doctor will monitor your response to treatment, assess for any side effects or complications, and adjust your treatment plan as needed.

By following your doctor’s instructions carefully and being aware of potential precautions and side effects, you can minimize risks and maximize the benefits of Tyzeka treatment for chronic hepatitis B infection.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Tyzeka. However, maintaining a healthy diet and avoiding excessive alcohol consumption can support overall liver health and complement hepatitis B treatment. Be sure to follow any dietary recommendations provided by your doctor or healthcare provider.

What should I do if I forget a dose?

If you miss a dose of Tyzeka, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure about what to do, contact your doctor or pharmacist for advice. It’s essential to maintain a consistent dosing schedule to maximize the effectiveness of Tyzeka in treating chronic hepatitis B infection.

What side effects can this medication cause?

Tyzeka (telbivudine) can cause various side effects, although not everyone will experience them. Common side effects of Tyzeka may include:

• Nausea: Feeling sick to your stomach, which may sometimes lead to vomiting.
• Fatigue: Unusual tiredness or lack of energy.
• Headache: Pain or discomfort in the head, ranging from mild to severe.
• Dizziness: Feeling lightheaded or unsteady.
• Muscle Weakness or Pain: Weakness or pain in the muscles, which may be mild or severe.
• Peripheral Neuropathy: Numbness, tingling, or weakness in the hands or feet.
• Upper Respiratory Tract Infections: Common cold-like symptoms such as stuffy or runny nose, sore throat, or cough.
• Abdominal Pain: Discomfort or pain in the abdominal area.
• Diarrhea: Frequent passing of loose, watery stools.
• Joint Pain: Pain or discomfort in the joints, such as the knees or elbows.

Less common but more severe side effects of Tyzeka may include:

• Liver Problems: Tyzeka can sometimes cause liver problems, including hepatomegaly (enlarged liver), hepatic steatosis (fatty liver), and in rare cases, severe liver damage.
• Pancreatitis: Inflammation of the pancreas, which may cause severe abdominal pain, nausea, and vomiting.
• Lactic Acidosis: A rare but serious condition characterized by a buildup of lactic acid in the blood, which can lead to weakness, rapid breathing, nausea, vomiting, and abdominal pain.
• Allergic Reactions: Some individuals may experience allergic reactions to Tyzeka, which can manifest as rash, itching, swelling, dizziness, or difficulty breathing.
• Exacerbation of Hepatitis B: Stopping Tyzeka treatment can sometimes lead to a sudden flare-up of hepatitis B infection, causing symptoms such as jaundice, abdominal pain, and fatigue.

It’s essential to report any side effects or symptoms you experience while taking Tyzeka to your healthcare provider promptly. They can assess the severity of the side effect and provide appropriate guidance or adjustments to your treatment plan if necessary.

What should I know about storage and disposal of this medication?

Storage and disposal of Tyzeka:

• Storage: Store Tyzeka tablets at room temperature away from light and moisture. Keep the medication in its original container and out of reach of children and pets.
• Disposal: Dispose of unused or expired Tyzeka tablets according to local regulations or guidelines. Do not flush them down the toilet or pour them down the drain unless instructed to do so. Instead, consult your pharmacist or local waste disposal facility for proper disposal methods.

In case of emergency/overdose

In case of an emergency or overdose of Tyzeka, contact your local poison control center (in the United States, call 1-800-222-1222) or seek emergency medical attention immediately. Overdose symptoms may include nausea, vomiting, abdominal pain, muscle weakness, or other adverse reactions.

What other information should I know?

• Regular Monitoring: Your doctor will likely monitor your liver function and hepatitis B viral load regularly while you’re taking Tyzeka. Attend all scheduled appointments for tests and follow-up visits.
• Follow-up Care: It’s essential to follow your doctor’s instructions carefully and complete the full course of Tyzeka treatment, even if you start to feel better. Stopping treatment prematurely can lead to the return of hepatitis B infection or development of drug resistance.
• Drug Interactions: Inform your doctor about all medications, supplements, or herbal products you are taking before starting Tyzeka treatment. Some medications may interact with Tyzeka, potentially affecting its effectiveness or increasing the risk of side effects.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of Tyzeka treatment with your healthcare provider. Tyzeka may cause harm to an unborn baby, and it’s not recommended during breastfeeding.
• Driving and Operating Machinery: Tyzeka may cause dizziness or drowsiness in some individuals. If you experience these side effects, avoid driving, operating machinery, or engaging in activities that require alertness until you know how Tyzeka affects you.
• Adherence to Instructions: Take Tyzeka exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider.
• Medical Alert: Inform other healthcare providers, including dentists and specialists, that you are taking Tyzeka before undergoing any medical procedures or surgeries.