Why is this medication prescribed?

Tyvaso is prescribed for the treatment of pulmonary arterial hypertension (PAH) in adults. PAH is a type of high blood pressure that affects the arteries in the lungs and the right side of the heart. Tyvaso works by dilating the blood vessels in the lungs, which helps to decrease blood pressure and improve blood flow, ultimately reducing the symptoms associated with PAH such as shortness of breath and fatigue.

How should this medicine be used?

Tyvaso is a medication that is inhaled through a nebulizer device. Here are general instructions on how to use Tyvaso:

• Preparation: Wash your hands thoroughly before handling the medication. Prepare the Tyvaso solution as directed by your healthcare provider and ensure that the nebulizer device is clean and assembled correctly.
• Administration: Sit or stand in an upright position. Place the mouthpiece of the nebulizer in your mouth, ensuring a tight seal around it. Breathe normally through the mouthpiece.
• Inhalation: Press the button on the nebulizer to start the medication delivery. Breathe in slowly and deeply through the mouthpiece. Continue inhaling the medication until the nebulizer stops producing mist, indicating that the dose is complete.
• Breathing technique: Try to inhale the medication as fully as possible into your lungs. Hold your breath for a few seconds before exhaling slowly through your mouth.
• Cleaning: After each use, follow the manufacturer’s instructions to clean the nebulizer device thoroughly. This helps prevent contamination and ensures proper functioning for the next use.
• Frequency: Tyvaso is typically administered 4 times daily, with doses spaced evenly throughout the day. Follow your healthcare provider’s instructions regarding the specific dosing schedule for your condition.
• Monitoring: Regularly monitor your symptoms and report any changes or concerns to your healthcare provider. They may adjust your Tyvaso dosage or treatment plan accordingly.

It’s essential to follow the instructions provided by your healthcare provider and the medication guide that comes with Tyvaso. If you have any questions or concerns about how to use Tyvaso properly, don’t hesitate to consult your healthcare provider or pharmacist for further guidance.

Other uses for this medicine

Apart from its primary use in treating PAH, there are no widely recognized alternative uses for Tyvaso. It’s essential to use this medication only as prescribed by your healthcare provider.

What special precautions should I follow?

Regarding special precautions for Tyvaso, here are some important points to consider:

• Allergies: Inform your healthcare provider if you are allergic to treprostinil or any other ingredients in Tyvaso.
• Medical History: Provide your healthcare provider with a comprehensive medical history, including any heart conditions, lung diseases, bleeding disorders, liver or kidney problems, or infections.
• Pregnancy and Breastfeeding: It’s essential to discuss the risks and benefits of using Tyvaso if you are pregnant or planning to become pregnant. Tyvaso should only be used during pregnancy if clearly needed. It’s also not known whether Tyvaso passes into breast milk, so consult your healthcare provider before breastfeeding while using Tyvaso.
• Interactions: Inform your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking, as Tyvaso may interact with certain drugs, potentially increasing the risk of side effects or reducing the effectiveness of either medication.
• Side Effects: Be aware of the potential side effects of Tyvaso, which may include cough, headache, throat irritation, nausea, dizziness, flushing, and low blood pressure. Contact your healthcare provider if you experience severe or persistent side effects.
• Nebulizer Maintenance: Follow proper cleaning and maintenance procedures for the nebulizer device to prevent contamination and ensure optimal delivery of the medication.
• Regular Monitoring: Your healthcare provider will monitor your response to Tyvaso treatment regularly, including assessing your symptoms, conducting tests, and adjusting your dosage as needed.

Always follow your healthcare provider’s instructions and recommendations regarding the use of Tyvaso and any other medications. If you have any questions or concerns about Tyvaso or its use, don’t hesitate to discuss them with your healthcare provider.

What special dietary instructions should I follow?

Regarding special dietary instructions for Tyvaso, there are no specific dietary restrictions associated with its use. However, maintaining a balanced diet and following any dietary recommendations provided by your healthcare provider can support overall health and may complement your treatment for pulmonary arterial hypertension.

What should I do if I forget a dose?

If you forget a dose of Tyvaso, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take extra doses to make up for the missed one. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Tyvaso (treprostinil) can cause a variety of side effects, ranging from mild to severe. It’s essential to be aware of these potential side effects and to promptly report any concerning symptoms to your healthcare provider. Some common side effects of Tyvaso include:

• Cough
• Headache
• Throat irritation
• Nausea
• Flushing (reddening of the skin)
• Dizziness
• Jaw pain
• Diarrhea
• Rash
• Low blood pressure (hypotension)

These side effects are typically mild to moderate and may improve over time as your body adjusts to the medication. However, if any of these side effects persist or worsen, or if you experience severe or concerning symptoms, it’s essential to contact your healthcare provider promptly.

In addition to the common side effects listed above, Tyvaso may also cause more serious side effects in some individuals. These can include:

• Syncope (fainting)
• Hemoptysis (coughing up blood)
• Hypersensitivity reactions, including anaphylaxis (severe allergic reaction)
• Infections, such as pneumonia
• Liver function abnormalities
• Worsening pulmonary hypertension
• Fluid retention
• Peripheral edema (swelling of the limbs)
• Bradycardia (slow heart rate)
• Thrombocytopenia (low platelet count)

It’s crucial to discuss any concerns or questions about side effects with your healthcare provider. They can provide guidance on managing side effects and may adjust your Tyvaso dosage or treatment plan if necessary. Additionally, if you experience any severe or life-threatening symptoms, seek immediate medical attention.

As with any medication, the benefits of Tyvaso should be weighed against the potential risks. Your healthcare provider will monitor you closely while you are taking Tyvaso to minimize the risk of side effects and ensure that you receive the most appropriate treatment for your condition.

What should I know about storage and disposal of this medication?

Storage and disposal of Tyvaso:

• Storage: Store Tyvaso ampules (unopened) in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze. Protect the Tyvaso ampules from light by storing them in their original carton until ready for use. Once opened, the Tyvaso ampules can be stored at room temperature (68°F to 77°F or 20°C to 25°C) for up to 7 days, protected from light.
• Disposal: Dispose of used Tyvaso ampules and any unused medication properly according to local regulations or guidelines. Do not flush Tyvaso down the toilet or pour it down the drain unless instructed to do so by your healthcare provider or pharmacist.

In case of emergency/overdose

If you suspect an overdose of Tyvaso or experience severe symptoms such as fainting, severe dizziness, difficulty breathing, or chest pain, seek immediate medical attention or contact a poison control center (1-800-222-1222 in the United States) for assistance. Be prepared to provide information about the medication and the amount ingested.

What other information should I know?

• Regular Follow-Up: Attend all scheduled appointments with your healthcare provider for monitoring and evaluation of your response to Tyvaso treatment.
• Medical Alert: Inform healthcare providers involved in your care, including emergency responders, about your use of Tyvaso. Wear a medical alert bracelet or carry a card indicating that you are taking Tyvaso in case of emergencies.
• Travel: If you plan to travel with Tyvaso, ensure that you have an adequate supply of medication and necessary equipment (such as the nebulizer device) for the duration of your trip. Follow appropriate storage and transportation guidelines for Tyvaso during travel.
• Refills: Ensure that you have a sufficient supply of Tyvaso on hand to prevent interruptions in treatment. Contact your healthcare provider or pharmacist in advance to arrange for refills as needed.
• Educational Resources: Take advantage of educational resources provided by your healthcare provider, pharmacist, or the medication manufacturer to learn more about Tyvaso, including its proper use, potential side effects, and other important information.
• Support Services: Consider seeking support from patient advocacy groups or support networks for individuals with pulmonary arterial hypertension to connect with others who may have similar experiences and concerns.

Always follow your healthcare provider’s instructions and recommendations regarding the use of Tyvaso and any other medications. If you have any questions or concerns about Tyvaso or its use, don’t hesitate to discuss them with your healthcare provider or pharmacist.