Why is this medication prescribed?

Capivasertib is a medication that belongs to a class of drugs known as AKT inhibitors. It is primarily prescribed for the treatment of certain types of cancer, particularly advanced solid tumors. Capivasertib works by inhibiting the activity of a protein called AKT, which plays a role in cell growth and survival. By blocking AKT, capivasertib can help slow down or stop the growth of cancer cells, thereby potentially slowing the progression of the disease. It may be prescribed in combination with other cancer treatments, such as chemotherapy or hormone therapy, depending on the specific type and stage of cancer being treated.

How should this medicine be used?

Capivasertib is typically used under the guidance and prescription of a qualified healthcare provider, such as an oncologist, who is experienced in prescribing cancer treatments. The specific dosage and regimen for Capivasertib can vary depending on factors such as the type of cancer being treated, the patient’s overall health, and individual response to the medication. However, here are some general guidelines on how Capivasertib is used:

• Dosage: The dosage of Capivasertib is determined by the healthcare provider based on various factors, including the patient’s body weight, overall health, and any other medications they may be taking. The dosage may also be adjusted over time based on the patient’s response to treatment and any side effects experienced.
• Administration: Capivasertib is typically available in the form of oral tablets. Patients are instructed to swallow the tablets whole with a glass of water. The tablets should not be crushed, chewed, or broken before swallowing.
• Timing: Capivasertib is usually taken once daily, although the specific timing may vary depending on the treatment regimen prescribed by the healthcare provider. Patients should follow the schedule provided by their doctor and take the medication at the same time each day to maintain consistent blood levels.
• Food Interactions: Capivasertib can be taken with or without food. Patients can choose whether to take the medication with meals or on an empty stomach based on their preferences and any specific recommendations from their healthcare provider.
• Duration of Treatment: The duration of treatment with Capivasertib varies depending on factors such as the type and stage of cancer being treated, as well as the individual response to the medication. Treatment may continue for as long as it remains effective in controlling the cancer and as long as the patient tolerates it well.
• Monitoring and Follow-up: Throughout the course of treatment with Capivasertib, patients will typically undergo regular monitoring by their healthcare provider. This may include periodic blood tests, imaging studies, and clinical evaluations to assess the response to treatment, monitor for any potential side effects, and make any necessary adjustments to the treatment plan.

It’s essential for patients to strictly adhere to the prescribed dosage and schedule for taking Capivasertib and to communicate regularly with their healthcare provider about any concerns, side effects, or changes in their condition. Only a qualified healthcare professional can determine the appropriate use of Capivasertib based on the individual patient’s needs and circumstances.

Other uses for this medicine

Other potential uses for capivasertib beyond its current approved indications in cancer treatment may be explored in clinical trials or off-label use. However, it’s crucial to note that any use of capivasertib beyond its approved indications should only be done under the guidance and supervision of a qualified healthcare professional.

What special precautions should I follow?

Regarding special precautions for using Capivasertib, here are some important points to consider:

• Medical History: Before starting Capivasertib treatment, inform your healthcare provider about your complete medical history, including any pre-existing conditions, allergies, or previous treatments. This information can help your doctor determine if Capivasertib is safe and appropriate for you.
• Pregnancy and Breastfeeding: Capivasertib may harm an unborn baby, so it is important to avoid becoming pregnant while taking this medication. Use effective birth control during treatment and for a period of time after the last dose. Additionally, breastfeeding is not recommended while taking Capivasertib, as it may pass into breast milk and harm the nursing infant.
• Liver Function: Capivasertib can affect liver function, so your doctor may monitor your liver enzymes with blood tests before and during treatment. If you have pre-existing liver problems, your doctor may adjust your dosage or closely monitor your liver function while you’re taking Capivasertib.
• Blood Sugar Levelsv: Capivasertib may cause changes in blood sugar levels, including hyperglycemia (high blood sugar) or hypoglycemia (low blood sugar). Patients with diabetes or those at risk of developing diabetes may require closer monitoring of their blood sugar levels during treatment.
• Infection Risk: Capivasertib can suppress the immune system, increasing the risk of infections. Inform your doctor promptly if you develop signs of infection such as fever, chills, cough, or difficulty breathing.
• Interactions with Other Medications: Before taking Capivasertib, inform your doctor about all the medications, supplements, and herbal products you are currently taking. Some medications may interact with Capivasertib, potentially affecting its effectiveness or increasing the risk of side effects.
• Side Effect Management: Be aware of the potential side effects of Capivasertib, such as nausea, diarrhea, fatigue, rash, and changes in blood sugar levels. Report any new or worsening symptoms to your doctor promptly.
• Follow-up Appointments: Attend all scheduled appointments with your healthcare provider for monitoring and follow-up during Capivasertib treatment. Regular check-ups and blood tests are important for assessing treatment response and managing any side effects.

It’s crucial to discuss any concerns or questions you have about Capivasertib with your healthcare provider. They can provide personalized guidance and address any specific precautions or considerations based on your individual medical history and treatment plan.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Capivasertib. However, maintaining a healthy and balanced diet is important for overall health and well-being, especially during cancer treatment. Your healthcare provider may recommend dietary modifications based on your individual health status and treatment regimen.

What should I do if I forget a dose?

If you miss a dose of Capivasertib, take it as soon as you remember, unless it is close to the time of your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure about what to do, contact your healthcare provider or pharmacist for advice.

Consistency in taking medication is essential for optimal treatment outcomes. If you frequently forget doses, consider setting reminders or using a pill organizer to help you stay on track with your medication schedule.

What side effects can this medication cause?

Capivasertib, like many medications, can cause side effects. It’s important to note that not all individuals will experience these side effects, and their severity can vary from person to person. Some potential side effects of Capivasertib may include:

• Gastrointestinal Disturbances: Nausea, vomiting, diarrhea, and abdominal pain are common side effects of Capivasertib. These symptoms can usually be managed with supportive care and may improve over time.
• Fatigue: Feeling tired or fatigued is a common side effect of Capivasertib. Getting adequate rest and practicing energy conservation techniques may help manage this symptom.
• Skin Reactions: Rash, itching, dry skin, and skin redness may occur with Capivasertib treatment. These side effects are usually mild to moderate in severity but should be reported to your healthcare provider if they become bothersome.
• Changes in Blood Sugar Levels: Capivasertib can affect blood sugar levels, leading to hyperglycemia (high blood sugar) or hypoglycemia (low blood sugar). Patients with diabetes or those at risk of developing diabetes may require closer monitoring of their blood sugar levels during treatment.
• Increased Risk of Infections: Capivasertib can suppress the immune system, increasing the risk of infections. Patients should promptly report any signs or symptoms of infection, such as fever, chills, cough, or difficulty breathing, to their healthcare provider.
• Liver Function Abnormalities: Capivasertib may affect liver function, leading to elevated liver enzymes. Your healthcare provider may monitor your liver function through blood tests during treatment.
• Musculoskeletal Symptoms: Muscle weakness, joint pain, and muscle spasms have been reported as side effects of Capivasertib.
• Cardiovascular Effects: Some patients may experience changes in blood pressure or heart rate while taking Capivasertib. These effects should be monitored by your healthcare provider.
• Other Potential Side Effects: Additional side effects may occur with Capivasertib treatment. It’s important to report any new or worsening symptoms to your healthcare provider for proper evaluation and management.

It’s essential to discuss any concerns or questions about side effects with your healthcare provider before starting Capivasertib treatment. They can provide personalized guidance and support to help manage side effects and optimize your treatment experience.

What should I know about storage and disposal of this medication?

Storage and disposal of Capivasertib:

• Storage: Capivasertib tablets should be stored at room temperature, away from moisture and heat. It’s essential to keep the medication in its original packaging and out of reach of children and pets. Avoid storing Capivasertib in the bathroom or other areas with high humidity.
• Disposal: Unused or expired Capivasertib tablets should be disposed of properly to prevent accidental ingestion or misuse. Follow any specific disposal instructions provided by your healthcare provider or pharmacist. You can also inquire about local medication take-back programs or follow FDA guidelines for safe drug disposal.

In case of emergency/overdose

In case of emergency or overdose of Capivasertib:

• Seek Medical Attention: If you suspect an overdose or experience severe adverse reactions after taking Capivasertib, seek immediate medical attention by calling emergency services or going to the nearest emergency room. Be sure to bring the medication container or information about the drug with you to help healthcare providers assess the situation.
• Symptom Management: Depending on the nature and severity of the overdose symptoms, medical professionals may administer supportive care, such as symptomatic treatment to alleviate discomfort, monitoring vital signs, or providing interventions as necessary.

What other information should I know?

• Follow-up Appointments: Attend all scheduled follow-up appointments with your healthcare provider while taking Capivasertib. These appointments are crucial for monitoring your response to treatment, assessing any side effects, and making any necessary adjustments to your treatment plan.
• Lab Tests: Your doctor may perform regular blood tests and other laboratory assessments to monitor your overall health and the effects of Capivasertib on your body. Follow your doctor’s instructions regarding these tests and inform them if you experience any unusual symptoms or side effects between appointments.
• Avoid Grapefruit: Grapefruit and grapefruit juice may interact with Capivasertib, potentially increasing the risk of side effects. Avoid consuming grapefruit or grapefruit products while taking this medication unless otherwise instructed by your healthcare provider.
• Patient Support Resources: Consider seeking support from patient advocacy groups or counseling services if you have questions or concerns about your diagnosis, treatment, or the emotional impact of cancer and its treatment.
• Medication Management: Take Capivasertib exactly as prescribed by your healthcare provider. Do not change your dose or stop taking the medication without consulting your doctor first. If you have any questions about your treatment regimen, speak with your healthcare provider or pharmacist for clarification.

Always follow your healthcare provider’s instructions and guidance for the safe and effective use of Capivasertib, and don’t hesitate to reach out to them if you have any questions or concerns.