Why is this medication prescribed?

Trilaciclib injection is a medication prescribed to reduce the risk of bone marrow suppression in patients undergoing certain types of chemotherapy. Bone marrow suppression can lead to decreased production of blood cells, including white blood cells, red blood cells, and platelets, which can result in increased susceptibility to infections, anemia, and bleeding. Trilaciclib works by inhibiting certain enzymes involved in the cell cycle, thereby protecting bone marrow cells from the toxic effects of chemotherapy.

How should this medicine be used?

Trilaciclib injection is typically administered by a healthcare professional as an intravenous infusion prior to the start of chemotherapy. The dosage and frequency of administration will depend on factors such as the specific chemotherapy regimen being used and the patient’s individual medical condition.

Here is a general guideline on how Trilaciclib injection is used:

• Administration: Trilaciclib injection is given as an intravenous infusion, meaning it is delivered directly into a vein over a period of time.
• Timing: It is usually administered shortly before the start of chemotherapy, typically within 30 minutes to 4 hours before chemotherapy infusion.
• Dosage: The dosage of Trilaciclib will be determined by your healthcare provider based on various factors, including your body weight, overall health, and the specific chemotherapy regimen being used.
• Monitoring: Your healthcare provider will monitor you closely during and after the infusion to watch for any potential side effects or adverse reactions.
• Follow-Up: Depending on your treatment plan, you may receive Trilaciclib injection before each cycle of chemotherapy. Follow your healthcare provider’s instructions carefully regarding the timing and frequency of Trilaciclib administration.

It’s essential to consult with your healthcare provider for specific instructions tailored to your individual needs and medical condition. They will provide guidance on the proper administration of Trilaciclib injection to ensure its effectiveness and safety.

Other uses for this medicine

Trilaciclib injection is primarily used to reduce the risk of bone marrow suppression in patients undergoing certain types of chemotherapy. However, it is always important to consult with a healthcare professional for specific guidance regarding any off-label uses of a medication.

What special precautions should I follow?

As for special precautions when using Trilaciclib injection, here are some key points to consider:

• Medical History: Inform your healthcare provider about any medical conditions you have, especially if you have a history of liver or kidney problems, as this may affect how Trilaciclib is prescribed or administered.
• Allergies: Let your healthcare provider know if you have any allergies to medications, including Trilaciclib or any of its ingredients.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Trilaciclib with your healthcare provider. It’s essential to weigh the potential benefits against any potential risks to the fetus or breastfeeding infant.
• Drug Interactions: Inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking, as Trilaciclib may interact with other drugs. This includes prescription medications, over-the-counter drugs, and vitamins.
• Side Effects: Be aware of potential side effects associated with Trilaciclib injection, such as nausea, fatigue, headache, dizziness, and changes in blood cell counts. Report any unusual or severe side effects to your healthcare provider promptly.
• Administration: Trilaciclib injection should only be administered by a healthcare professional trained in its use. Follow your healthcare provider’s instructions carefully regarding dosage, timing, and frequency of administration.
• Storage: Store Trilaciclib injection according to the instructions provided by the manufacturer. Keep it out of reach of children and away from heat, moisture, and light.

Always follow your healthcare provider’s guidance and instructions when using Trilaciclib injection to ensure its safe and effective use. If you have any questions or concerns, don’t hesitate to discuss them with your healthcare provider.

What special dietary instructions should I follow?

Regarding special dietary instructions for Trilaciclib Injection, there are typically no specific dietary restrictions associated with its use. However, it’s always a good idea to maintain a healthy and balanced diet to support overall health and well-being during cancer treatment.

What should I do if I forget a dose?

If you forget a dose of Trilaciclib Injection, it’s important to contact your healthcare provider or treatment team for guidance. They can advise you on the appropriate course of action based on your specific situation. Do not try to double up on doses or make up for missed doses without consulting a healthcare professional first.

What side effects can this medication cause?

Trilaciclib Injection, like any medication, can cause side effects, although not everyone experiences them. Some common side effects associated with Trilaciclib Injection may include:

• Nausea
• Fatigue
• Headache
• Dizziness
• Vomiting
• Diarrhea
• Constipation
• Decreased appetite
• Changes in taste
• Injection site reactions (pain, redness, swelling)
• Changes in blood cell counts (such as low white blood cell count, low red blood cell count, or low platelet count)

These side effects are usually mild to moderate in severity and tend to improve over time as the body adjusts to the medication. However, if any of these side effects persist or worsen, it’s important to inform your healthcare provider.

In addition to the common side effects listed above, Trilaciclib Injection may also cause more serious side effects in some cases. These can include allergic reactions, severe infusion reactions, liver problems, and others. While uncommon, it’s essential to be aware of the signs of these serious side effects and seek medical attention immediately if they occur.

It’s important to note that this is not a comprehensive list of all possible side effects associated with Trilaciclib Injection. Always consult with your healthcare provider for personalized information about the potential side effects of any medication you are prescribed, as well as guidance on how to manage them.

What should I know about storage and disposal of this medication?

Storage and disposal of Trilaciclib Injection:

Storage:

• Temperature: Trilaciclib Injection should be stored at controlled room temperature, typically between 20°C to 25°C (68°F to 77°F).
• Protection from Light: Keep the vials of Trilaciclib Injection protected from light.
• Refrigeration: If the medication needs to be stored long-term or if instructed by the manufacturer, it may be stored in a refrigerator. However, consult the product labeling or your healthcare provider for specific storage instructions.
• Avoid Freezing: Do not freeze Trilaciclib Injection.
• Do Not Shake: Avoid shaking the vials excessively.

Disposal:

• Unused Medication: Dispose of any unused Trilaciclib Injection properly according to local regulations or as instructed by your healthcare provider or pharmacist.
• Sharps Disposal: Dispose of needles, syringes, and other materials used to prepare and administer Trilaciclib Injection in a puncture-resistant container as per local guidelines.

In case of emergency/overdose

In case of an emergency or suspected overdose of Trilaciclib Injection, contact emergency medical services (e.g., call your local emergency number) immediately. You can also contact a poison control center for guidance on next steps.

What other information should I know?

• Follow Instructions: Always follow the instructions provided by your healthcare provider or pharmacist regarding the administration, storage, and disposal of Trilaciclib Injection.
• Keep Appointments: Attend all scheduled appointments with your healthcare provider for monitoring and follow-up during treatment with Trilaciclib Injection.
• Inform Healthcare Providers: Keep your healthcare provider informed about any other medications, supplements, or herbal products you are taking, as well as any changes in your health status.
• Report Side Effects: If you experience any side effects or adverse reactions while using Trilaciclib Injection, notify your healthcare provider promptly.
• Pregnancy/Breastfeeding: Discuss the risks and benefits of using Trilaciclib Injection if you are pregnant, planning to become pregnant, or breastfeeding.

Always consult with your healthcare provider or pharmacist if you have any questions or concerns regarding the storage, disposal, or use of Trilaciclib Injection.