Why is this medication prescribed?

Toujeo is prescribed to help manage blood sugar levels in people with diabetes mellitus. Specifically, it is used to control high blood sugar levels in adults and children with type 1 diabetes mellitus and adults with type 2 diabetes mellitus.

Toujeo belongs to the class of medications known as long-acting insulin analogs. It works by replacing the insulin that the body produces naturally but is either not producing enough of or is unable to properly utilize. By providing a steady level of insulin throughout the day, Toujeo helps to regulate blood sugar levels and prevent complications associated with high blood sugar, such as kidney damage, nerve damage, vision problems, and cardiovascular issues.

Ultimately, the goal of prescribing Toujeo is to help individuals with diabetes maintain better control over their blood sugar levels, leading to improved overall health and a reduced risk of diabetes-related complications. However, it’s important to note that Toujeo should be used as part of a comprehensive diabetes management plan, which may include dietary modifications, regular exercise, and other medications as determined by a healthcare provider.

How should this medicine be used?

Here’s how Toujeo is typically used:

• Dosage: The dosage of Toujeo is individualized based on factors like the patient’s blood sugar levels, medical history, other medications they may be taking, and their response to treatment. Your healthcare provider will determine the appropriate dose for you.
• Administration: Toujeo is administered via subcutaneous injection (injected under the skin). It should not be administered intravenously or intramuscularly.
• Frequency: Toujeo is usually injected once a day at the same time each day. It is important to maintain a consistent dosing schedule to help stabilize blood sugar levels.
• Injection sites: Toujeo can be injected into the abdomen, thigh, or upper arm. Rotate injection sites within the same region to reduce the risk of developing lipodystrophy (changes in fat distribution at the injection site).
• Monitoring: Regular monitoring of blood sugar levels is essential while using Toujeo. Your healthcare provider may recommend periodic adjustments to your insulin dose based on your blood sugar readings.
• Storage: Toujeo should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). Once in use, it can be kept at room temperature (59°F to 86°F or 15°C to 30°C) for up to 28 days. Avoid exposure to direct sunlight and extreme heat or cold.
• Precautions: Follow your healthcare provider’s instructions carefully, including any dietary or lifestyle modifications recommended to manage your diabetes effectively. Inform your healthcare provider about any other medications, including over-the-counter drugs and supplements, you are taking, as they may interact with Toujeo.

It’s important to note that Toujeo should be used as part of a comprehensive diabetes management plan, which may include diet, exercise, and other medications as prescribed by your healthcare provider. Always consult your healthcare provider for personalized advice regarding the use of Toujeo and diabetes management.

Other uses for this medicine

Toujeo (insulin glargine) is primarily used for the management of diabetes mellitus, as discussed earlier. However, there are no other approved medical uses for Toujeo beyond its intended purpose in diabetes management. It’s essential to only use Toujeo under the guidance and prescription of a healthcare provider and for the specific condition it is intended to treat.

What special precautions should I follow?

Regarding special precautions for using Toujeo, here are some important considerations:

• Hypoglycemia (Low Blood Sugar): Toujeo can cause hypoglycemia, especially if the dose is too high or if not enough food is consumed after taking the medication. Symptoms of hypoglycemia include sweating, trembling, rapid heartbeat, confusion, and dizziness. Patients should be educated on recognizing and managing hypoglycemia.
• Hyperglycemia (High Blood Sugar): It’s essential to monitor blood sugar levels regularly while using Toujeo to prevent hyperglycemia. High blood sugar can lead to serious complications if left untreated.
• Dosage Adjustment: Toujeo dosage may need adjustment based on factors such as changes in diet, exercise habits, illness, stress, or other medications being taken. Always consult with a healthcare provider before making any changes to your insulin dosage.
• Injection Technique: Proper injection technique is crucial to ensure the effective delivery of insulin and to minimize the risk of complications such as injection site reactions or improper dosing. Patients should receive proper training on how to administer Toujeo injections.
• Hypokalemia: Insulin use, including Toujeo, may lead to a decrease in potassium levels in the blood (hypokalemia). Patients should be monitored for signs of hypokalemia, such as muscle weakness, fatigue, and irregular heartbeat.
• Driving and Operating Machinery: Hypoglycemia can impair your ability to concentrate and react, which may affect your ability to drive or operate machinery. Be cautious if you experience low blood sugar levels while using Toujeo.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult with your healthcare provider before using Toujeo. Adjustments to your diabetes management plan may be necessary during these times.
• Storage: Store Toujeo according to the manufacturer’s instructions, typically in the refrigerator before first use and at room temperature once in use. Avoid exposure to extreme temperatures and direct sunlight.

Always follow your healthcare provider’s instructions and advice regarding the use of Toujeo and any special precautions specific to your individual health needs.

What special dietary instructions should I follow?

Special dietary instructions for Toujeo may vary depending on your individual health needs and diabetes management plan. However, in general:

• Consistent Meal Timing: Try to maintain a consistent schedule for meals and snacks to help stabilize blood sugar levels. Aim for a balanced diet that includes carbohydrates, protein, and healthy fats.
• Carbohydrate Monitoring: Be mindful of your carbohydrate intake, as carbohydrates have the most significant impact on blood sugar levels. Your healthcare provider or a registered dietitian can help you determine an appropriate carbohydrate intake for your individual needs.
• Glycemic Index: Some people with diabetes find it helpful to consider the glycemic index (GI) of foods when planning meals. Foods with a lower GI typically cause a slower increase in blood sugar levels.

What should I do if I forget a dose?

If you forget a dose of Toujeo, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure about what to do, consult with your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Toujeo (insulin glargine) can cause side effects, although not everyone experiences them. Common side effects of Toujeo may include:

• Hypoglycemia: Low blood sugar levels are the most common side effect of insulin therapy, including Toujeo. Symptoms of hypoglycemia may include sweating, trembling, rapid heartbeat, confusion, dizziness, weakness, and hunger.
• Injection Site Reactions: You may experience redness, swelling, itching, or pain at the injection site. Rotating injection sites can help minimize these reactions.
• Hypersensitivity Reactions: Some individuals may experience allergic reactions to insulin, although this is rare. Symptoms may include rash, itching, difficulty breathing, or swelling of the face, lips, tongue, or throat.
• Hypokalemia: Insulin use, including Toujeo, may lead to a decrease in potassium levels in the blood (hypokalemia), which can cause symptoms such as muscle weakness, fatigue, and irregular heartbeat.
• Weight Gain: Some people may experience weight gain while using insulin therapy, including Toujeo. This weight gain may be due to improved glycemic control and increased appetite.
• Fluid Retention: Insulin therapy may cause fluid retention, leading to swelling in the legs, ankles, or feet.
• Vision Changes: Fluctuations in blood sugar levels may temporarily affect vision, causing blurred vision or changes in vision.
• Lipodystrophy: Prolonged use of insulin at the same injection site may lead to lipodystrophy, which is a thickening or thinning of the fatty tissue under the skin at the injection site.

It’s important to note that these lists are not exhaustive, and other side effects may occur. Additionally, everyone’s response to medication can vary, so some individuals may experience side effects not listed here. If you experience any concerning or persistent side effects while using Toujeo, contact your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

Storage and disposal of Toujeo:

• Storage: Toujeo should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C) until the expiration date mentioned on the packaging. Do not freeze Toujeo. Once in use, Toujeo can be stored at room temperature (59°F to 86°F or 15°C to 30°C) for up to 28 days. Keep Toujeo away from direct sunlight and extreme temperatures. Do not use Toujeo if it has been frozen or exposed to temperatures outside the recommended range.
• Disposal: Dispose of used Toujeo injection devices (pens or syringes) properly in a puncture-resistant container. Do not dispose of Toujeo in household trash. Follow local regulations or ask your healthcare provider or pharmacist about the proper disposal method for used injection devices.

In case of emergency/overdose

• Symptoms of hypoglycemia (low blood sugar) due to overdose or misuse of Toujeo may include confusion, sweating, shakiness, blurred vision, dizziness, or fainting.
• If you suspect an overdose or experience severe hypoglycemia symptoms, seek emergency medical attention immediately.
• Have a glucagon emergency kit readily available for severe hypoglycemia. Family members, caregivers, or close contacts should know how to administer glucagon in case of an emergency.

What other information should I know?

• Inform your healthcare provider about any allergies, medical conditions, or medications you are taking before starting Toujeo.
• Follow your healthcare provider’s instructions carefully regarding dosage and administration of Toujeo.
• Monitor your blood sugar levels regularly as directed by your healthcare provider.
• Be aware of signs and symptoms of both hypoglycemia and hyperglycemia (high blood sugar) and know how to manage them.
• Attend regular follow-up appointments with your healthcare provider to assess your response to Toujeo and make any necessary adjustments to your treatment plan.
• Keep emergency contact information, including your healthcare provider’s phone number and the nearest emergency medical services, readily available.

Always consult with your healthcare provider or pharmacist for personalized advice and guidance regarding the storage, disposal, and use of Toujeo. They can provide specific recommendations based on your individual needs and circumstances.