Why is this medication prescribed?

Tosymra Nasal Spray is prescribed for the treatment of acute migraine headaches with or without aura in adults. It contains sumatriptan, which belongs to a class of drugs known as triptans. Sumatriptan works by narrowing blood vessels in the brain and reducing substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. It is important to note that Tosymra Nasal Spray is not intended for the prevention of migraines or for the treatment of other types of headaches. It should only be used to treat acute migraine attacks as they occur.

How should this medicine be used?

Tosymra Nasal Spray should be used according to the following instructions:

• Prepare the Nasal Spray: Before using Tosymra, remove the protective cap from the nasal spray bottle. If you are using the nasal spray for the first time or if you haven’t used it for a while, you may need to prime the pump by pumping it a few times until a fine mist appears.
• Position Yourself: Stand or sit in an upright position. Tilt your head slightly forward and close one nostril by pressing gently with your finger.
• Administer the Spray: Insert the tip of the nasal spray bottle into the open nostril. Be sure to aim the spray away from the center of your nose, towards the outer wall. This helps to minimize irritation and increase the effectiveness of the medication. Press down firmly on the pump to release one spray of Tosymra into your nostril while breathing in gently through your nose.
• Breathe Normally: Breathe gently through your nose to allow the medication to be absorbed into the nasal passages.
• Repeat for the Other Nostril: If your healthcare provider has instructed you to use Tosymra in both nostrils, repeat the process for the other nostril.
• Avoid Blowing Your Nose: Try to avoid blowing your nose immediately after using Tosymra, as this can reduce the effectiveness of the medication.
• Dispose of the Nasal Spray: Replace the protective cap on the nasal spray bottle and store it in a safe place. Dispose of any unused medication properly according to local regulations.

It’s important to follow the specific instructions provided by your healthcare provider regarding the dosage and frequency of use. Do not exceed the recommended dose, and consult your doctor if you have any questions or concerns about how to use Tosymra Nasal Spray.

Other uses for this medicine

Tosymra Nasal Spray is primarily indicated for the acute treatment of migraine headaches in adults and is not typically used for other purposes. However, there may be instances where a healthcare provider prescribes it off-label for other types of headaches or conditions. Off-label use should only be done under the guidance and supervision of a qualified healthcare professional.

What special precautions should I follow?

As with any medication, there are special precautions to consider when using Tosymra Nasal Spray. These precautions include:

• Allergies: Inform your healthcare provider if you have a known allergy to sumatriptan or any other ingredients in Tosymra Nasal Spray. Allergic reactions can include rash, itching, swelling, severe dizziness, or trouble breathing, and may require immediate medical attention.
• Medical History: Discuss your medical history with your healthcare provider, particularly if you have a history of certain medical conditions such as heart disease, high blood pressure, liver or kidney problems, seizures, or risk factors for stroke. These conditions may affect your suitability for using Tosymra.
• Drug Interactions: Inform your healthcare provider about all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications, such as other triptans, selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and certain monoamine oxidase inhibitors (MAOIs), may interact with Tosymra Nasal Spray and increase the risk of serious side effects.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Tosymra Nasal Spray with your healthcare provider. It is essential to weigh the potential risks to the fetus or infant against the potential benefits of migraine relief.
• Driving and Operating Machinery: Tosymra Nasal Spray may cause dizziness or drowsiness in some individuals. Avoid driving, operating machinery, or engaging in activities requiring mental alertness until you know how this medication affects you.
• Overuse: Avoid using Tosymra Nasal Spray more frequently than prescribed, as overuse can lead to medication overuse headaches or rebound headaches.

Always follow the instructions provided by your healthcare provider and the medication’s prescribing information. If you have any questions or concerns about using Tosymra Nasal Spray, consult your healthcare provider for guidance.

What special dietary instructions should I follow?

Special dietary instructions for Tosymra Nasal Spray are not typically provided. However, it’s essential to maintain a balanced diet and stay hydrated, especially during a migraine episode.

What should I do if I forget a dose?

If you forget a dose of Tosymra Nasal Spray, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure about what to do, consult your healthcare provider or pharmacist for advice.

What side effects can this medication cause?

Tosymra Nasal Spray, like any medication, can cause side effects. Some common side effects of Tosymra Nasal Spray include:

• Nasal Discomfort: This may include irritation, burning sensation, or unusual taste in the mouth.
• Dizziness or Drowsiness: Some individuals may experience feelings of dizziness or drowsiness after using Tosymra Nasal Spray.
• Nausea or Vomiting: These gastrointestinal symptoms may occur in some users.
• Muscle Weakness: Weakness or fatigue in the muscles is a possible side effect.
• Chest Discomfort: This may include tightness, pressure, or pain in the chest.
• Tingling or Numbness: Some people may experience sensations of tingling or numbness, particularly in the hands or feet.
• Throat Discomfort: Sore throat or irritation in the throat may occur.
• Increased Blood Pressure: Tosymra Nasal Spray can occasionally cause an increase in blood pressure, particularly in individuals with pre-existing hypertension.
• Serotonin Syndrome: This is a rare but potentially serious reaction characterized by symptoms such as confusion, hallucinations, fever, sweating, shivering, rapid heart rate, and seizures. Seek immediate medical attention if you experience any of these symptoms.
• Allergic Reactions: Allergic reactions to Tosymra Nasal Spray can occur, leading to symptoms such as rash, itching, swelling, severe dizziness, or trouble breathing. If you experience any signs of an allergic reaction, seek medical attention promptly.

It’s essential to discuss any side effects you experience with your healthcare provider, especially if they are persistent or severe. They can provide guidance on managing side effects or adjusting your treatment regimen if necessary. Additionally, if you experience any unusual or concerning symptoms after using Tosymra Nasal Spray, seek medical attention promptly.

What should I know about storage and disposal of this medication?

Storage and disposal of Tosymra Nasal Spray:

• Storage: Store Tosymra Nasal Spray at room temperature away from light and moisture. Avoid storing it in the bathroom. Keep the nasal spray bottle tightly closed when not in use.
• Disposal: Dispose of any unused Tosymra Nasal Spray properly according to local regulations. Do not flush it down the toilet or pour it into a drain unless instructed to do so. Consult your pharmacist or healthcare provider for guidance on the proper disposal method.

In case of emergency/overdose

In case of emergency or overdose of Tosymra Nasal Spray:

• Seek Immediate Medical Attention: If you suspect an overdose or experience severe symptoms such as chest pain, severe dizziness, seizures, or loss of consciousness, seek emergency medical assistance immediately. Call your local emergency services or go to the nearest emergency room.
• Contact Poison Control: You can also contact your local poison control center or call the Poison Help hotline at 1-800-222-1222 for guidance on what to do next.

What other information should I know?

• Effectiveness: Tosymra Nasal Spray is most effective when used as soon as migraine symptoms appear. It is not intended for the prevention of migraines or for the treatment of other types of headaches.
• Usage: Follow the instructions provided by your healthcare provider for the proper use of Tosymra Nasal Spray. Do not exceed the recommended dosage or frequency of use.
• Monitoring: Keep track of your migraine symptoms and response to treatment while using Tosymra Nasal Spray. If you notice any changes or have concerns about its effectiveness or side effects, discuss them with your healthcare provider.
• Interactions: Inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, as they may interact with Tosymra Nasal Spray.
• Storage: Keep Tosymra Nasal Spray out of reach of children and pets. Store it in a secure location to prevent accidental ingestion.

By following these guidelines and staying informed about Tosymra Nasal Spray, you can use it safely and effectively for the treatment of acute migraine headaches.