WARNING

Tolsura is a medication used to treat certain fungal infections. Like any medication, it carries potential risks and side effects. Some of the risks associated with taking Tolsura include:

• Allergic reactions: Some individuals may experience allergic reactions to Tolsura, which can range from mild to severe. Symptoms may include rash, itching, swelling, dizziness, or difficulty breathing.
• Liver toxicity: Tolsura can cause liver damage or liver failure in some cases. Patients may experience symptoms such as jaundice (yellowing of the skin or eyes), dark urine, abdominal pain, or unexplained fatigue.
• Drug interactions: Tolsura may interact with other medications, potentially altering their effectiveness or increasing the risk of side effects. It’s important for patients to inform their healthcare provider about all medications they are taking before starting Tolsura.
• Gastrointestinal side effects: Common side effects of Tolsura include nausea, vomiting, diarrhea, and abdominal pain. These symptoms may be mild and transient or more severe and persistent.
• Central nervous system effects: Tolsura may cause dizziness, headache, or other central nervous system side effects in some individuals.
• Cardiovascular effects: In rare cases, Tolsura may cause abnormal heart rhythms or other cardiovascular problems.
• Bone marrow suppression: Tolsura may suppress the bone marrow’s ability to produce blood cells, leading to anemia, leukopenia (low white blood cell count), or thrombocytopenia (low platelet count).
• Other potential risks: Tolsura may also have other, less common side effects or risks not listed here. Patients should discuss any concerns with their healthcare provider and report any unusual symptoms experienced while taking Tolsura.

It’s important for patients to weigh the potential risks and benefits of Tolsura with their healthcare provider before starting treatment, and to closely follow their provider’s instructions for use.

Why is this medication prescribed?

Tolsura is typically prescribed to treat certain fungal infections caused by specific types of fungi, including Blastomyces dermatitidis, Histoplasma capsulatum, and Candida species. These infections can affect various parts of the body, including the lungs, skin, and other organs. Tolsura belongs to a class of medications called azole antifungals, which work by inhibiting the growth of fungi.

The dosage and duration of treatment with Tolsura can vary depending on the type and severity of the fungal infection, as well as the patient’s medical history and response to the medication. It’s essential to follow the prescribing healthcare provider’s instructions carefully and complete the full course of treatment, even if symptoms improve before the medication is finished.

How should this medicine be used?

Tolsura is an oral medication typically used to treat certain fungal infections. Here’s a general overview of how Tolsura should be used:

• Dosage: The dosage of Tolsura prescribed by your healthcare provider will depend on factors such as the type and severity of the fungal infection, your medical history, and your response to the medication. Always follow your healthcare provider’s instructions regarding dosage carefully.
• Administration: Tolsura is usually taken orally, which means it is swallowed by mouth. It can be taken with or without food. The capsules should be swallowed whole with a full glass of water. Do not crush, chew, or break the capsules before swallowing, as this can affect the medication’s effectiveness.
• Timing: Take Tolsura exactly as prescribed by your healthcare provider. It’s essential to take it at the same time(s) each day to maintain a consistent level of the medication in your body.
• Duration: The duration of treatment with Tolsura will vary depending on the type and severity of the fungal infection. It’s crucial to complete the full course of treatment prescribed by your healthcare provider, even if your symptoms improve before you finish the medication. Stopping treatment prematurely can lead to the recurrence of the infection or the development of drug-resistant fungi.
• Missed Dose: If you miss a dose of Tolsura, take it as soon as you remember, unless it’s almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
• Monitoring: Your healthcare provider may monitor your progress while taking Tolsura to ensure the medication is working effectively and to watch for any potential side effects or complications. Be sure to attend all scheduled appointments and inform your provider of any changes in your condition.
• Storage: Store Tolsura capsules at room temperature away from moisture, heat, and light. Keep the medication out of reach of children and pets.

Always consult your healthcare provider if you have any questions or concerns about how to use Tolsura properly. It’s essential to follow their instructions closely for safe and effective treatment.

Other uses for this medicine

As for other uses of Tolsura, it’s primarily indicated for treating fungal infections, particularly those caused by certain types of fungi such as Aspergillus, Blastomyces, Histoplasma, and others. Its use for other conditions would typically be off-label and would require careful consideration and supervision by a healthcare provider.

What special precautions should I follow?

As for special precautions to follow when taking Tolsura, here are some key points to keep in mind:

• Allergies: Inform your healthcare provider if you have any allergies to Tolsura or any other medications. It’s crucial to disclose any known allergies or sensitivities to avoid potential adverse reactions.
• Medical history: Provide your healthcare provider with a comprehensive medical history, including any past or present medical conditions, especially liver disease or kidney disease. Tolsura may require dose adjustments or special monitoring in these situations.
• Pregnancy and breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The use of Tolsura during pregnancy or breastfeeding should be carefully considered based on the potential risks and benefits, and your healthcare provider will advise accordingly.
• Drug interactions: Tolsura may interact with other medications, supplements, or herbal products. Make sure to inform your healthcare provider about all medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and supplements. Your provider can assess potential interactions and adjust your treatment plan as needed.
• Liver function monitoring: Tolsura can affect liver function, so your healthcare provider may order regular blood tests to monitor your liver function during treatment. Contact your provider immediately if you experience symptoms of liver problems, such as yellowing of the skin or eyes (jaundice), dark urine, abdominal pain, or unexplained fatigue.
• Side effects: Be aware of potential side effects of Tolsura, such as gastrointestinal symptoms (nausea, vomiting, diarrhea), dizziness, headache, or allergic reactions. If you experience any concerning side effects, contact your healthcare provider for further evaluation and guidance.
• Follow-up: Attend all scheduled follow-up appointments with your healthcare provider to monitor your progress, discuss any concerns or side effects, and ensure the effectiveness of treatment.

By following these precautions and working closely with your healthcare provider, you can help ensure the safe and effective use of Tolsura for your specific condition.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Tolsura. However, it’s essential to maintain a balanced diet and stay hydrated while taking the medication. If you have any concerns about diet or nutrition while taking Tolsura, consult your healthcare provider or a registered dietitian for personalized advice.

What should I do if I forget a dose?

If you miss a dose of Tolsura, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you are unsure about what to do, contact your healthcare provider or pharmacist for guidance. It’s essential to maintain a consistent dosing schedule to ensure the effectiveness of Tolsura in treating your condition.

What side effects can this medication cause?

Tolsura, like any medication, can cause side effects in some individuals. Common side effects of Tolsura may include:

• Gastrointestinal symptoms: Nausea, vomiting, diarrhea, and abdominal pain are among the most common side effects of Tolsura. These symptoms are usually mild and may improve over time.
• Headache: Some individuals may experience headaches while taking Tolsura.
• Dizziness: Tolsura may cause dizziness or lightheadedness in some people.
• Changes in taste: Tolsura can sometimes alter the sense of taste, causing a metallic or unpleasant taste in the mouth.
• Rash or itching: Skin rash or itching may occur as a side effect of Tolsura in some individuals.
• Elevated liver enzymes: Tolsura may cause increases in liver enzymes, which can indicate liver inflammation or damage. Your healthcare provider may monitor your liver function with blood tests during treatment.
• Fatigue: Some people may experience fatigue or tiredness while taking Tolsura.
• Other side effects: Less common side effects of Tolsura may include allergic reactions, such as swelling of the face, lips, or tongue, difficulty breathing, or severe skin reactions. If you experience any signs of an allergic reaction, seek medical attention immediately.

It’s essential to report any unusual or severe side effects to your healthcare provider promptly. They can help determine whether the side effect is related to Tolsura and provide guidance on managing it. Additionally, if you have concerns about potential side effects or if you experience any symptoms that are bothersome or persistent, consult your healthcare provider for further evaluation and advice.

What should I know about storage and disposal of this medication?

Storage and disposal of Tolsura:

• Storage: Store Tolsura capsules at room temperature, away from moisture, heat, and light. Keep the medication out of reach of children and pets. Do not store Tolsura in the bathroom, as moisture and humidity can affect its stability.
• Disposal: Dispose of any unused or expired Tolsura capsules properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Instead, consult with your pharmacist or healthcare provider on the appropriate disposal method.

In case of emergency/overdose

In case of an emergency or overdose involving Tolsura, seek immediate medical attention or contact your local poison control center. Symptoms of overdose may include severe nausea, vomiting, dizziness, fainting, or difficulty breathing.

What other information should I know?

• Keep all appointments with your healthcare provider for monitoring and follow-up during Tolsura treatment.
• Inform all healthcare providers involved in your care that you are taking Tolsura, including dentists and pharmacists.
• Avoid consuming alcohol while taking Tolsura, as it may increase the risk of liver problems.
• If you are prescribed any new medications or supplements while taking Tolsura, inform your healthcare provider to avoid potential drug interactions.
• Do not share Tolsura with others, even if they have similar symptoms or conditions, as it may not be suitable for them.
• Follow your healthcare provider’s instructions carefully regarding dosage, timing, and duration of Tolsura treatment.
• Report any unusual or severe side effects to your healthcare provider promptly.
• If you have any questions or concerns about Tolsura or its use, consult your healthcare provider or pharmacist for clarification.

By following these guidelines and staying informed about Tolsura, you can help ensure safe and effective use of the medication for your specific condition.