WARNING

Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain and inflammation. While it can be effective for certain conditions, it is important to be aware of potential risks associated with its use. Here are some key points:

• Gastrointestinal Effects: Tolmetin, like other NSAIDs, may increase the risk of gastrointestinal ulcers, bleeding, and perforation. This risk is higher in older adults and those with a history of stomach or intestinal issues.
• Cardiovascular Risks: NSAIDs, including tolmetin, may increase the risk of cardiovascular events such as heart attack or stroke, especially with prolonged use or in individuals with pre-existing cardiovascular conditions.
• Kidney Function: Long-term use of NSAIDs can affect kidney function, potentially leading to kidney problems. Individuals with pre-existing kidney conditions should exercise caution when using tolmetin.
• Allergic Reactions: Some people may experience allergic reactions to tolmetin, which can manifest as rash, itching, swelling, severe dizziness, or difficulty breathing. If any of these symptoms occur, medical attention should be sought immediately.
• Liver Function: Tolmetin can affect liver function, and individuals with liver disease or pre-existing liver conditions should use it cautiously and under medical supervision.
• Blood Disorders: NSAIDs, including tolmetin, may interfere with blood clotting and increase the risk of bleeding. Individuals with bleeding disorders or those taking anticoagulant medications should consult their healthcare provider before using tolmetin.
• Fluid Retention and Hypertension: NSAIDs can cause fluid retention and high blood pressure. This is particularly relevant for individuals with pre-existing hypertension or heart conditions.
• Pregnancy and Breastfeeding: Tolmetin should be used with caution during pregnancy, especially in the third trimester, as it may harm the unborn baby. It can also pass into breast milk, so breastfeeding mothers should consult with their healthcare provider before using it.

It’s crucial to use tolmetin as prescribed by a healthcare professional, and individuals should inform their doctor of any existing medical conditions, medications, or allergies before starting this medication. Regular check-ups and monitoring for side effects are essential during the course of treatment. If any concerning symptoms arise, it is important to seek medical advice promptly.

Why is this medication prescribed?

Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) that is prescribed to relieve pain and reduce inflammation associated with various conditions. It is commonly used for the following purposes:

• Rheumatoid Arthritis: Tolmetin is prescribed to manage the symptoms of rheumatoid arthritis, an autoimmune disorder that causes joint inflammation, pain, and stiffness.
• Osteoarthritis: It may be used to alleviate pain and inflammation associated with osteoarthritis, a degenerative joint disease characterized by the breakdown of joint cartilage.
• Ankylosing Spondylitis: Tolmetin can be prescribed to treat ankylosing spondylitis, an inflammatory arthritis affecting the spine and large joints.
• Acute Gout: In some cases, tolmetin may be used to relieve pain and inflammation during acute gout attacks.
• Mild to Moderate Pain: Tolmetin can be prescribed for short-term relief of mild to moderate pain, such as that caused by injuries, dental procedures, or menstrual cramps.

How should this medicine be used?

The dosage and duration of Tolmetin use depend on the specific condition being treated, the severity of symptoms, and individual patient factors. It’s important to follow the doctor’s prescription and instructions carefully. Here are general guidelines for using Tolmetin:

• Dosage: The typical starting dose for adults is 400 mg every 8 hours. However, the dosage may vary based on the individual’s condition and response to the medication.
• Administration: Tolmetin is usually taken with food or milk to minimize the risk of gastrointestinal irritation. The tablets should be swallowed whole with a full glass of water.
• Duration: The duration of treatment varies, and it is typically prescribed for the shortest duration necessary to control symptoms. Long-term use may increase the risk of side effects.
• Regular Monitoring: While using Tolmetin, it’s essential to have regular check-ups with the healthcare provider to monitor for potential side effects and adjust the treatment plan if needed.
• Caution in Certain Populations: Special caution is required in older adults, those with a history of stomach or intestinal issues, individuals with cardiovascular or kidney conditions, and pregnant or breastfeeding women.
• Avoid Alcohol and Other NSAIDs: It is advisable to avoid alcohol and other NSAIDs while taking Tolmetin to reduce the risk of side effects and interactions.

Patients should inform their healthcare provider about any existing medical conditions, medications, or allergies before starting Tolmetin. If there are concerns or if side effects occur, it is crucial to seek prompt medical advice. Abruptly stopping the medication without consulting a healthcare professional is not recommended.

Other uses for this medicine

While tolmetin is primarily prescribed to relieve pain and inflammation associated with arthritis and other musculoskeletal conditions, it’s important to note that any use of medication should be under the guidance and prescription of a healthcare professional. Off-label use, or use for conditions not explicitly approved by regulatory authorities, should be avoided without proper medical supervision.

What special precautions should I follow?

Special precautions should be taken when using tolmetin, and individuals should be aware of the following considerations:

• Medical History: Before starting tolmetin, inform your healthcare provider about your complete medical history, including any pre-existing conditions such as heart disease, high blood pressure, kidney problems, liver disease, gastrointestinal issues, asthma, or bleeding disorders.
• Allergies: Individuals with a known allergy to tolmetin, other NSAIDs, or aspirin should avoid using tolmetin.
• Pregnancy and Breastfeeding: Tolmetin should be used cautiously during pregnancy, particularly in the third trimester, as it may pose risks to the unborn baby. It can also pass into breast milk, so breastfeeding mothers should consult with their healthcare provider before using it.
• Elderly Population: Older adults may be more susceptible to the side effects of tolmetin, especially gastrointestinal bleeding and kidney problems. Lower doses may be considered in this population.
• Cardiovascular Risks: Tolmetin, like other NSAIDs, may increase the risk of cardiovascular events, such as heart attack or stroke. This risk may be higher in individuals with pre-existing cardiovascular conditions.
• Kidney Function: Long-term use of NSAIDs, including tolmetin, can affect kidney function. Individuals with pre-existing kidney conditions should use it cautiously and under medical supervision.
• Gastrointestinal Effects: Tolmetin may increase the risk of gastrointestinal ulcers, bleeding, and perforation. It’s important to inform the healthcare provider if there is a history of stomach or intestinal issues.
• Other Medications: Inform your doctor about all other medications, including over-the-counter drugs, herbal supplements, and vitamins, as they may interact with tolmetin.
• Alcohol: Limit alcohol intake while using tolmetin, as it can increase the risk of gastrointestinal bleeding.
• Monitoring: Regular monitoring by a healthcare provider is essential to check for potential side effects and adjust the treatment plan if needed.

Always take tolmetin as prescribed, and do not exceed the recommended dosage. If you experience any concerning symptoms or side effects, seek medical attention promptly. It’s crucial to follow the healthcare provider’s guidance and attend regular check-ups for proper monitoring.

What special dietary instructions should I follow?

Special Dietary Instructions for Tolmetin:

• Take with Food: To minimize the risk of gastrointestinal irritation, take tolmetin with food or milk.
• Avoid Grapefruit Juice: Grapefruit juice may interact with tolmetin, affecting its absorption. It’s advisable to avoid grapefruit juice while taking this medication.

What should I do if I forget a dose?

• If it’s Close to the Next Dose: If you miss a dose and it’s almost time for the next one, skip the missed dose. Take the next dose at the scheduled time.
• If it’s Not Close to the Next Dose: If you remember a missed dose and it’s not close to the time for the next one, take it as soon as possible. However, if it’s almost time for the next dose, skip the missed one.
• Do Not Double Dose: Do not take a double dose to make up for a missed one. Taking more than the prescribed amount can increase the risk of side effects.

What side effects can this medication cause?

Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce inflammation and relieve pain. Like all medications, it can potentially cause side effects. Common side effects of tolmetin may include:

• Gastrointestinal Effects: NSAIDs, including tolmetin, can irritate the stomach lining and lead to gastrointestinal issues. This may include stomach pain, indigestion, heartburn, nausea, and in rare cases, ulcers or bleeding.
• Cardiovascular Effects: NSAIDs have been associated with an increased risk of cardiovascular events, such as heart attack or stroke. This risk may be higher in individuals with existing cardiovascular conditions.
• Renal (Kidney) Effects: NSAIDs can affect kidney function, leading to fluid retention, high blood pressure, or worsening of pre-existing kidney problems. In severe cases, NSAIDs may cause kidney failure.
• Hematologic Effects: Tolmetin may affect blood clotting, leading to an increased risk of bleeding. This is more likely to occur in individuals with bleeding disorders or those taking blood-thinning medications.
• Allergic Reactions: Some people may be allergic to tolmetin, leading to symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing. Allergic reactions can be serious and require immediate medical attention.
• Liver Effects: In rare cases, NSAIDs may cause liver problems, including liver inflammation or damage.

It’s important to note that these are potential side effects, and not everyone will experience them. The risk of side effects may increase with higher doses or prolonged use of the medication. Individuals with certain pre-existing conditions, such as cardiovascular disease, kidney problems, or a history of gastrointestinal issues, may be at a higher risk of experiencing side effects.

Before using tolmetin or any other medication, it is crucial to consult with a healthcare professional. They can assess your medical history, evaluate the potential risks and benefits, and provide guidance on the appropriate use of the medication. If you experience any unusual or severe symptoms while taking tolmetin, seek medical attention promptly.

What should I know about storage and disposal of this medication?

Storage and Disposal of Tolmetin:

• Storage:
  • Store tolmetin at room temperature, away from moisture and heat.
  • Keep it in its original container, tightly closed.
• Disposal:
  • Dispose of expired or unused tolmetin properly according to local regulations or guidelines.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms, seek emergency medical attention immediately. Overdose symptoms may include:

• Extreme drowsiness
• Nausea or vomiting
• Severe stomach pain
• Difficulty breathing
• Fainting
• Coma

What other information should I know?

• Regular Monitoring: Attend regular check-ups with your healthcare provider to monitor the effectiveness of tolmetin and watch for potential side effects.
• Avoiding Alcohol: Limit alcohol intake while taking tolmetin to reduce the risk of gastrointestinal bleeding.
• Interactions: Inform your healthcare provider about all medications, including over-the-counter drugs, herbal supplements, and vitamins, as they may interact with tolmetin.
• Allergic Reactions: If you experience signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.
• Pregnancy and Breastfeeding: Consult your healthcare provider before using tolmetin if you are pregnant or breastfeeding.
• Kidney Function: Individuals with pre-existing kidney conditions should use tolmetin cautiously and under medical supervision.
• Gastrointestinal Effects: Inform your healthcare provider if you have a history of stomach or intestinal issues.
• Follow Prescribed Dosage: Take tolmetin exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage.
• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it’s almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double up on doses.
• Caution in Elderly Population: Older adults may be more susceptible to certain side effects, so lower doses may be considered.

Always follow your healthcare provider’s instructions and guidelines for the safe and effective use of tolmetin. If you have any questions or concerns about the medication, consult with your healthcare professional.