WARNING

Tekturna (generic name: aliskiren) is a medication primarily used to treat high blood pressure (hypertension). Like any medication, Tekturna comes with potential risks and side effects. Here are some of the key risks associated with taking Tekturna:

• Hypotension (low blood pressure): Tekturna can cause a significant drop in blood pressure, especially when first starting the medication or when the dosage is increased. This can lead to symptoms such as dizziness, fainting, and weakness.
• Kidney problems: Tekturna can impair kidney function, particularly in individuals with pre-existing kidney disease or those taking other medications that affect the kidneys. This can manifest as increased levels of potassium in the blood (hyperkalemia) or decreased kidney function.
• Hyperkalemia: Tekturna may increase potassium levels in the blood, which can be dangerous, especially for individuals with kidney problems or those taking other medications that can also raise potassium levels.
• Allergic reactions: Some people may experience allergic reactions to Tekturna, which can range from mild skin rashes to more severe symptoms such as swelling of the face, throat, or tongue, and difficulty breathing.
• Birth defects: Tekturna is not recommended for use during pregnancy as it may cause harm to the fetus, including birth defects or death. It’s important for women of childbearing age to use effective contraception while taking Tekturna.
• Interaction with other medications: Tekturna may interact with other medications, including certain diuretics (water pills), potassium supplements, and nonsteroidal anti-inflammatory drugs (NSAIDs), which can increase the risk of side effects or reduce its effectiveness.
• Other side effects: Other potential side effects of Tekturna include diarrhea, flu-like symptoms, cough, and fatigue.

It’s essential for individuals considering or currently taking Tekturna to discuss the potential risks and benefits with their healthcare provider, as well as to follow their provider’s instructions carefully. Additionally, regular monitoring of blood pressure, kidney function, and potassium levels may be necessary while taking Tekturna to mitigate potential risks.

Why is this medication prescribed?

Tekturna (generic name: aliskiren) is prescribed primarily for the treatment of high blood pressure (hypertension). It belongs to a class of medications known as direct renin inhibitors, which work by blocking the activity of renin, an enzyme involved in regulating blood pressure.

Here are some key reasons why Tekturna may be prescribed:

• Hypertension: Tekturna is commonly used to lower blood pressure in individuals with hypertension, either alone or in combination with other antihypertensive medications.
• Diabetic nephropathy: In individuals with type 2 diabetes and kidney disease (diabetic nephropathy), Tekturna may be prescribed to help slow the progression of kidney damage and reduce the risk of cardiovascular events.
• Heart failure: Tekturna may be used as part of the treatment regimen for heart failure, particularly in individuals who also have hypertension or diabetes.
• Other cardiovascular conditions: In some cases, Tekturna may be prescribed for other cardiovascular conditions as determined by a healthcare provider.

How should this medicine be used?

Tekturna (generic name: aliskiren) is a medication primarily used to treat high blood pressure (hypertension). It’s important to use Tekturna exactly as prescribed by your healthcare provider. Here are some general guidelines on how Tekturna should be used:

• Dosage: Take Tekturna exactly as directed by your healthcare provider. The usual recommended starting dose for adults is 150 mg once daily. Your doctor may adjust the dosage based on your blood pressure response. The maximum recommended dose is 300 mg once daily.
• Administration: Take Tekturna orally with a full glass of water. You can take it with or without food.
• Timing: Try to take Tekturna at the same time each day to maintain a consistent level of the medication in your body.
• Do not crush or chew: Swallow Tekturna tablets whole with water. Do not crush, chew, or break the tablets, as this can affect the medication’s efficacy and increase the risk of side effects.
• Missed dose: If you miss a dose of Tekturna, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
• Do not stop abruptly: It’s essential not to stop taking Tekturna without consulting your healthcare provider, even if you feel well. Suddenly stopping Tekturna can cause your blood pressure to increase rapidly.
• Regular monitoring: Your healthcare provider may monitor your blood pressure regularly while you’re taking Tekturna to assess its effectiveness and adjust the dosage if needed. They may also monitor your kidney function and potassium levels, especially if you have pre-existing kidney problems or are at risk of hyperkalemia (high potassium levels).
• Follow other recommendations: In addition to taking Tekturna, follow any other recommendations provided by your healthcare provider to help manage your high blood pressure. This may include lifestyle modifications such as maintaining a healthy diet, exercising regularly, reducing salt intake, limiting alcohol consumption, and avoiding tobacco products.
• Keep appointments: Attend all scheduled appointments with your healthcare provider to monitor your blood pressure and overall health.
• Storage: Store Tekturna at room temperature away from moisture, heat, and light. Keep it out of reach of children and pets.

If you have any questions or concerns about how to use Tekturna, don’t hesitate to consult your healthcare provider or pharmacist for guidance. They can provide personalized advice based on your individual health status and medication regimen.

Other uses for this medicine

Some of the other potential uses for Tekturna include:

• Diabetic nephropathy: Tekturna may be prescribed to individuals with type 2 diabetes and kidney disease (diabetic nephropathy) to help slow the progression of kidney damage and reduce the risk of cardiovascular events.
• Heart failure: Tekturna may be used as part of the treatment regimen for heart failure, particularly in individuals who also have hypertension or diabetes.
• Other cardiovascular conditions: In some cases, Tekturna may be prescribed for other cardiovascular conditions, such as reducing the risk of stroke or heart attack, as determined by a healthcare provider.

What special precautions should I follow?

Regarding special precautions for Tekturna, here are some key considerations:

• Pregnancy and breastfeeding: Tekturna should not be used during pregnancy as it may cause harm to the fetus, including birth defects or death. It’s essential for women of childbearing age to use effective contraception while taking Tekturna. Additionally, Tekturna may pass into breast milk, so breastfeeding while taking Tekturna is not recommended.
• Kidney function: Tekturna can affect kidney function, particularly in individuals with pre-existing kidney disease. Regular monitoring of kidney function, including blood tests to assess kidney function and potassium levels, may be necessary while taking Tekturna.
• Potassium levels: Tekturna may increase potassium levels in the blood (hyperkalemia), especially in individuals with kidney problems or those taking other medications that can also raise potassium levels. Monitoring of potassium levels may be necessary, and concurrent use of potassium supplements or potassium-sparing diuretics should be avoided unless directed by a healthcare provider.
• Allergic reactions: Some people may experience allergic reactions to Tekturna, which can range from mild skin rashes to more severe symptoms such as swelling of the face, throat, or tongue, and difficulty breathing. Patients should seek medical attention immediately if they experience signs of an allergic reaction.
• Interaction with other medications: Tekturna may interact with other medications, including certain diuretics (water pills), potassium supplements, and nonsteroidal anti-inflammatory drugs (NSAIDs), which can increase the risk of side effects or reduce its effectiveness. It’s essential to inform healthcare providers about all medications being taken, including prescription, over-the-counter, and herbal supplements, to avoid potential interactions.
• Hypotension (low blood pressure): Tekturna can cause a significant drop in blood pressure, especially when first starting the medication or when the dosage is increased. This can lead to symptoms such as dizziness, fainting, and weakness. Patients should be cautious when standing up from a sitting or lying position to minimize the risk of falls.

Overall, it’s important for individuals considering or currently taking Tekturna to discuss the potential risks and benefits with their healthcare provider and to follow their provider’s instructions carefully. Regular monitoring and follow-up appointments may be necessary to ensure safe and effective use of Tekturna.

What special dietary instructions should I follow?

Special dietary instructions:

• Potassium-rich foods: Since Tekturna may increase potassium levels, it’s important to be mindful of your intake of potassium-rich foods such as bananas, oranges, potatoes, tomatoes, and spinach. Consult your healthcare provider or a dietitian for personalized dietary recommendations.
• Salt intake: Limiting salt (sodium) intake may help enhance the effectiveness of Tekturna in managing high blood pressure. Aim to follow a balanced diet with moderate salt intake.

What should I do if I forget a dose?

• If you forget to take a dose of Tekturna, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.
• If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance on managing missed doses.

What side effects can this medication cause?

Tekturna (aliskiren) can cause various side effects, although not everyone experiences them. Common side effects may include:

• Diarrhea: Some individuals may experience diarrhea while taking Tekturna. This side effect is usually mild and temporary.
• Dizziness: Tekturna can cause dizziness, especially when standing up quickly from a sitting or lying position. This symptom may occur, particularly at the beginning of treatment or when the dosage is increased.
• Cough: Coughing is a possible side effect of Tekturna. If persistent or bothersome, consult your healthcare provider.
• Fatigue: Feeling tired or fatigued may occur as a side effect of Tekturna.
• Headache: Headaches are a potential side effect of Tekturna, although they are usually mild.

Less common but more serious side effects of Tekturna include:

• Allergic reactions: Some individuals may experience allergic reactions to Tekturna, which can manifest as skin rash, itching, swelling of the face, lips, tongue, or throat, difficulty breathing, or severe dizziness. Seek immediate medical attention if you experience signs of an allergic reaction.
• Hypotension (low blood pressure): Tekturna can cause a significant drop in blood pressure, leading to symptoms such as dizziness, lightheadedness, fainting, or weakness. This effect is more common in individuals with pre-existing low blood pressure or those taking other medications that lower blood pressure.
• Kidney problems: Tekturna may affect kidney function, particularly in individuals with pre-existing kidney disease. Symptoms of kidney problems may include changes in urination (frequency, color, or amount), swelling in the feet or ankles, or unexplained weight gain.
• Hyperkalemia (high potassium levels): Tekturna may increase potassium levels in the blood, which can lead to symptoms such as muscle weakness, irregular heartbeat, or tingling sensations. Monitoring of potassium levels may be necessary, especially in individuals with kidney problems or those taking other medications that raise potassium levels.
• Liver problems: Rarely, Tekturna may cause liver problems, which can manifest as jaundice (yellowing of the skin or eyes), dark urine, persistent nausea or vomiting, or abdominal pain.

It’s essential to report any unusual or severe side effects to your healthcare provider promptly. They can provide guidance on managing side effects or adjust your treatment regimen if necessary. Additionally, do not stop taking Tekturna without consulting your healthcare provider, even if you experience side effects.

What should I know about storage and disposal of this medication?

When it comes to the storage and disposal of Tekturna, here are some important considerations:

• Storage:
  • Store Tekturna tablets at room temperature away from moisture, heat, and light.
  • Keep Tekturna out of reach of children and pets.
  • Do not store Tekturna in the bathroom or kitchen, as moisture and heat can affect the medication’s stability.
• Disposal:
  • Dispose of unused or expired Tekturna tablets properly according to local guidelines or regulations.
  • Do not flush Tekturna down the toilet or pour it down the drain unless instructed to do so by your healthcare provider or pharmacist.
  • Consult your pharmacist or local waste disposal authority for instructions on how to safely dispose of Tekturna.

In case of emergency/overdose

• In case of an emergency or suspected overdose of Tekturna, call your local emergency services or go to the nearest emergency room immediately.
• Symptoms of overdose may include extreme dizziness or lightheadedness, fainting, rapid or irregular heartbeat, weakness, or severe diarrhea.
• If possible, bring the medication bottle or packaging to the emergency room to help healthcare providers determine the appropriate treatment.

What other information should I know?

• Keep all appointments with your healthcare provider for regular check-ups and monitoring while taking Tekturna.
• Inform your healthcare provider about all other medications, supplements, or herbal products you are taking, as they may interact with Tekturna.
• Avoid alcohol while taking Tekturna, as it may increase the risk of side effects such as dizziness or low blood pressure.
• If you are undergoing surgery or any medical procedures, inform your healthcare provider that you are taking Tekturna.
• Follow your healthcare provider’s instructions regarding dietary restrictions, lifestyle modifications, and other aspects of managing hypertension or other conditions for which Tekturna is prescribed.
• If you have any questions or concerns about Tekturna or its use, consult your healthcare provider or pharmacist for guidance.

It’s crucial to follow these guidelines to ensure the safe and effective use of Tekturna and to minimize the risk of adverse effects or complications. If you have any doubts or questions, don’t hesitate to seek clarification from your healthcare provider or pharmacist.