Why is this medication prescribed?

Tasimelteon is primarily prescribed to treat Non-24-Hour Sleep-Wake Disorder (Non-24), a circadian rhythm sleep disorder. Non-24 is more commonly observed in individuals who are totally blind and, as a result, lack the light perception necessary for regulating their circadian rhythm. The circadian rhythm is the natural, internal process that regulates the sleep-wake cycle and repeats roughly every 24 hours.

How should this medicine be used?

Tasimelteon is a melatonin receptor agonist, specifically targeting the melatonin receptors in the brain. Melatonin is a hormone produced by the pineal gland that helps regulate the sleep-wake cycle. Tasimelteon helps synchronize the sleep-wake cycle by mimicking the effects of melatonin.

How to Use Tasimelteon:

• Dosage: Follow your healthcare provider’s prescribed dosage. The typical recommended dose is usually taken once daily, within 30 minutes of the intended bedtime.
• Administration: Tasimelteon can be taken with or without food.
• Consistency: Take Tasimelteon at the same time each night to help regulate your sleep-wake cycle.
• Avoidance of Grapefruit: As mentioned earlier, it’s advisable to avoid grapefruit or grapefruit products, as they can interact with Tasimelteon.
• Regular Follow-up: Keep regular follow-up appointments with your healthcare provider to assess the effectiveness of the medication and to make any necessary adjustments to your treatment plan.

Always follow your healthcare provider’s instructions precisely and communicate any concerns or side effects you may experience. If you have questions about your prescription or how to take Tasimelteon, consult your healthcare provider or pharmacist for clarification. It’s crucial to use Tasimelteon as prescribed to achieve the best results in managing Non-24-Hour Sleep-Wake Disorder.

Other uses for this medicine

Tasimelteon is primarily indicated for Non-24-Hour Sleep-Wake Disorder, and its use for other conditions may be limited. Always consult with your healthcare provider for information about potential alternative treatments or uses.

What special precautions should I follow?

Special Precautions for Tasimelteon:

• Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Tasimelteon during pregnancy or breastfeeding is not well-established.
• Liver Impairment: Inform your healthcare provider if you have liver problems, as Tasimelteon is metabolized in the liver. Adjustments to the dosage may be necessary for individuals with liver impairment.
• Drug Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking. Tasimelteon may interact with certain medications.
• Allergies: If you are allergic to Tasimelteon or any of its components, inform your healthcare provider.
• Driving and Operating Machinery: Tasimelteon may cause drowsiness, so it’s important to evaluate how it affects you before engaging in activities that require alertness, such as driving or operating machinery.
• Side Effects: Be aware of potential side effects, such as headache, elevated liver enzymes, and abnormal dreams. Report any unusual or severe side effects to your healthcare provider.
• Regular Check-ups: Attend regular follow-up appointments with your healthcare provider to monitor the effectiveness of the treatment and address any concerns.

Always follow your healthcare provider’s instructions, and inform them of your complete medical history to ensure safe and effective use of Tasimelteon. If you have specific concerns or questions, consult your healthcare provider for personalized advice based on your health condition.

What special dietary instructions should I follow?

Special Dietary Instructions for Tasimelteon:

• Food: Tasimelteon can be taken with or without food. There are no specific dietary restrictions associated with Tasimelteon.
• Alcohol: While there is no direct interaction between Tasimelteon and alcohol, excessive alcohol intake can affect sleep patterns. Discuss your alcohol consumption with your healthcare provider.

What should I do if I forget a dose?

If you forget to take a dose of Tasimelteon, follow these general guidelines:

• Take it as soon as you remember: If you forget a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double up: Avoid taking a double dose to make up for a missed one. Taking more than the prescribed amount can lead to unwanted side effects.
• Consult your healthcare provider: If you are unsure about what to do if you miss a dose, contact your healthcare provider for guidance.

What side effects can this medication cause?

Tasimelteon, like any medication, may cause side effects. It’s important to note that not everyone will experience these side effects, and some individuals may experience side effects that are not listed. If you are prescribed Tasimelteon, closely monitor your response to the medication and inform your healthcare provider of any unusual or severe symptoms. Common side effects of Tasimelteon may include:

• Headache: Headache is one of the more commonly reported side effects.
• Elevated Liver Enzymes: Tasimelteon may cause an increase in liver enzymes. Regular monitoring of liver function is usually recommended.
• Abnormal Dreams: Some individuals may experience vivid or abnormal dreams while taking Tasimelteon.
• Upper Respiratory Tract Infections: Respiratory infections such as the common cold may occur.
• Nightmares: Nightmares or unusual dreams have been reported as a side effect.
• Influenza: Some people may experience symptoms resembling influenza.
• Nausea: Nausea is a possible side effect, though it’s not very common.

It’s important to contact your healthcare provider if you experience any severe or persistent side effects. Additionally, if you notice any signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek medical attention immediately.

Remember that this is not an exhaustive list of side effects, and individual responses to medication can vary. Always consult with your healthcare provider for personalized information based on your medical history and current health status.

What should I know about storage and disposal of this medication?

Storage and Disposal of Tasimelteon:

• Storage: Keep Tasimelteon at room temperature, away from excessive heat and moisture. Do not freeze the medication. Store it in its original packaging or container, and keep it out of reach of children.
• Disposal: Dispose of Tasimelteon in accordance with local regulations. Do not flush it down the toilet or throw it in the trash unless instructed to do so. Your healthcare provider or pharmacist can provide guidance on proper disposal methods.

In case of emergency/overdose

In case of an emergency or suspected overdose, seek immediate medical attention or contact a poison control center. Signs of overdose may include excessive drowsiness, confusion, and potential respiratory depression. Provide healthcare professionals with information about the amount of Tasimelteon ingested, if known.

What other information should I know?

• Follow-up appointments: Keep regular follow-up appointments with your healthcare provider to monitor the effectiveness of Tasimelteon and discuss any concerns or potential side effects.
• Inform healthcare providers: Inform other healthcare providers, including dentists and emergency room staff, about your use of Tasimelteon. This is important for comprehensive medical care and to avoid potential drug interactions.
• Melatonin supplements: If you are taking melatonin supplements or other products containing melatonin, discuss this with your healthcare provider. Combining Tasimelteon with other melatonin-containing products may lead to an increased risk of side effects.
• Avoid alcohol: While there is no direct interaction between Tasimelteon and alcohol, it’s advisable to limit or avoid alcohol consumption as excessive alcohol intake can affect sleep patterns.
• Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. The safety of Tasimelteon in these situations is not well-established.

Always consult with your healthcare provider or pharmacist if you have specific questions or concerns about Tasimelteon. They can provide personalized advice based on your health status and medical history.