Why is this medication prescribed?

Tadalafil is a medication primarily prescribed to treat erectile dysfunction (ED) in men. It belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Tadalafil works by increasing blood flow to the penis during sexual stimulation, helping men achieve and maintain an erection.

In addition to treating ED, Tadalafil is also prescribed for the management of symptoms of benign prostatic hyperplasia (BPH), which is an enlargement of the prostate gland. It can help improve urinary symptoms associated with BPH, such as difficulty urinating, incomplete emptying of the bladder, and the need to urinate frequently or urgently.

How should this medicine be used?

Here are general guidelines for the use of Tadalafil:

• Dosage: The typical starting dose for Tadalafil is 10 mg, taken prior to anticipated sexual activity. However, the dose may be adjusted based on individual response and tolerability. Your healthcare provider will determine the appropriate dosage for you.
• Timing: Tadalafil is usually taken at least 30 minutes before sexual activity. The effects may last up to 36 hours, earning it the nickname “the weekend pill.” However, it’s important to note that sexual stimulation is still required to achieve an erection.
• Frequency: The medication is generally taken as needed, but not more than once per day. If you are prescribed Tadalafil for the management of BPH symptoms, it may be taken once daily regardless of sexual activity.
• Food Interaction: Tadalafil can be taken with or without food. However, taking it with a high-fat meal may delay the onset of action.
• Avoid Alcohol: Excessive alcohol consumption can increase the risk of side effects, so it’s advisable to limit alcohol intake while using Tadalafil.
• Missed Dose: If Tadalafil is used as needed for ED, there is no specific dosing schedule. Take it when needed and do not exceed one dose in a 24-hour period.
• Consultation with Healthcare Provider: It’s crucial to follow your healthcare provider’s instructions and discuss any concerns or questions you may have about the medication. They will consider factors such as your overall health, existing medical conditions, and potential interactions with other medications.

As with any prescription medication, only use Tadalafil under the supervision of a qualified healthcare professional. Do not self-prescribe or exceed the recommended dosage without consulting your healthcare provider, as this may increase the risk of side effects. If you experience any adverse effects or have concerns about the medication, seek medical attention promptly.

Other uses for this medicine

Some off-label uses include:

• Pulmonary Arterial Hypertension (PAH): Tadalafil has been approved for the treatment of pulmonary arterial hypertension in some countries. It works by relaxing the blood vessels in the lungs, reducing the workload on the heart.
• Raynaud’s Phenomenon: Some studies have suggested that Tadalafil may help improve symptoms in patients with Raynaud’s phenomenon, a condition that affects blood flow to certain parts of the body, typically the fingers and toes.

What special precautions should I follow?

As for special precautions when using Tadalafil, here are some important considerations:

• Medical History: Inform your healthcare provider of your complete medical history, especially if you have or have had heart problems, low or high blood pressure, liver or kidney disease, a history of stroke, or any eye problems.
• Medication Interactions: Tadalafil can interact with certain medications, including nitrates (often prescribed for chest pain), alpha-blockers (commonly used to treat high blood pressure and BPH), and some antifungal medications. It’s important to inform your healthcare provider about all the medications, including over-the-counter drugs and supplements, that you are taking.
• Heart Conditions: Tadalafil can cause a sudden decrease in blood pressure, particularly if taken with other medications that lower blood pressure. This can be dangerous for individuals with pre-existing heart conditions.
• Vision Changes: In rare cases, Tadalafil may cause changes in vision or sudden loss of vision. If you experience any changes in vision while taking the medication, seek medical attention immediately.
• Priapism: In rare instances, Tadalafil may lead to a prolonged erection (priapism) that can be painful and may cause damage to the penis. If an erection lasts longer than 4 hours, seek medical attention.
• Allergies: If you are allergic to Tadalafil or any of its ingredients, do not use the medication.

Always follow your healthcare provider’s instructions and inform them of any concerns or side effects you may experience while using Tadalafil. It’s essential to have a thorough discussion about your medical history and current medications to ensure the safe and effective use of Tadalafil.

What special dietary instructions should I follow?

Tadalafil can be taken with or without food. However, taking it with a high-fat meal may delay the onset of action. While there are no specific dietary restrictions associated with Tadalafil, it’s advisable to maintain a healthy lifestyle, including a balanced diet and regular exercise, to support overall cardiovascular health.

What should I do if I forget a dose?

If you are using Tadalafil for the management of benign prostatic hyperplasia (BPH) or pulmonary arterial hypertension (PAH) on a daily basis and forget a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

What side effects can this medication cause?

Tadalafil, like any medication, can cause side effects. Not everyone will experience these side effects, and their severity can vary. It’s essential to be aware of potential side effects and to promptly contact your healthcare provider if you experience any concerning symptoms. Common side effects of Tadalafil include:

• Headache: This is one of the most commonly reported side effects.
• Flushing (warmth or redness in the face, neck, or chest): Some individuals may experience a feeling of warmth or redness in the upper body.
• Indigestion or upset stomach: Tadalafil may cause gastrointestinal discomfort, including indigestion or upset stomach.
• Back pain: Some people may experience back pain as a side effect of Tadalafil.
• Muscle aches: Tadalafil can cause muscle aches, particularly in the back and legs.
• Nasal congestion: Some individuals may experience a stuffy or runny nose.
• Dizziness: Tadalafil can cause dizziness or lightheadedness, especially when getting up from a sitting or lying position.
• Vision changes: In rare cases, Tadalafil may cause changes in vision or sudden loss of vision. Seek medical attention if you experience any vision problems.
• Priapism: This is a rare but serious side effect involving a prolonged and sometimes painful erection. If an erection lasts longer than 4 hours, seek immediate medical attention.

It’s important to note that not everyone will experience these side effects, and some individuals may experience side effects not listed here. Additionally, serious allergic reactions to Tadalafil are rare but require immediate medical attention if they occur. Seek emergency medical help if you experience symptoms such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing.

It’s crucial to discuss any concerns about side effects with your healthcare provider before starting Tadalafil. Your healthcare provider will assess your overall health and consider potential interactions with other medications you may be taking. If you experience any unexpected or severe side effects while taking Tadalafil, seek prompt medical attention.

What should I know about storage and disposal of this medication?

Storage and Disposal of Tadalafil:

• Storage:
  • Store Tadalafil at room temperature, away from light and moisture.
  • Keep it out of reach of children and pets.
  • Do not store the medication in the bathroom, where moisture and humidity may affect its stability.
• Disposal:
  • Dispose of unused or expired Tadalafil in a proper and environmentally friendly manner.
  • Follow local regulations for medication disposal, and consider using drug take-back programs or community disposal programs.
  • Do not flush Tadalafil down the toilet unless specifically instructed to do so.

In case of emergency/overdose

In case of an emergency or suspected overdose with Tadalafil, seek medical attention or contact a poison control center immediately. The symptoms of an overdose may include severe dizziness, fainting, or prolonged erections.

What other information should I know?

• Avoid Alcohol: Excessive alcohol consumption can increase the risk of side effects associated with Tadalafil, including dizziness and headache. Limit alcohol intake while using this medication.
• Grapefruit Juice Interaction: Avoid consuming grapefruit or grapefruit juice while taking Tadalafil, as it may increase the levels of the medication in your blood and enhance the risk of side effects.
• Consultation with Healthcare Provider: Always consult with your healthcare provider before starting or stopping Tadalafil. Discuss any existing medical conditions, medications, or concerns you may have.
• Sexual Activity and Heart Health: If you have a history of heart problems, consult with your healthcare provider before engaging in sexual activity, as Tadalafil can affect blood pressure.
• Non-prescription Use: Do not use Tadalafil without a prescription, and do not share the medication with others.
• Regular Check-ups: If you are using Tadalafil for the treatment of erectile dysfunction or other conditions, attend regular check-ups with your healthcare provider to monitor your health and adjust the treatment plan if necessary.
• Patient Information Leaflet: Read the patient information leaflet provided with the medication for additional details and guidance.

As with any medication, it’s crucial to follow your healthcare provider’s instructions and to be vigilant about potential interactions or side effects. If you have any questions or concerns about Tadalafil, do not hesitate to discuss them with your healthcare provider.