Why is this medication prescribed?

Tabrecta (capmatinib) is a prescription medication used to treat certain types of non-small cell lung cancer (NSCLC). It is specifically indicated for the treatment of metastatic NSCLC with mutations that lead to mesenchymal-epithelial transition (MET) exon 14 skipping. MET exon 14 skipping alterations are genetic mutations that can drive the growth and spread of cancer cells.

How should this medicine be used?

Here are some general guidelines for using Tabrecta:

• Dosage: The recommended dosage can vary, and it is determined by the healthcare provider based on factors such as the patient’s weight, overall health, and any other medical conditions.
• Administration: Tabrecta is usually taken orally, with or without food. The tablets should be swallowed whole with water and not crushed or split.
• Schedule: The medication is typically taken at the same time each day to maintain a consistent level in the body.
• Follow-up: Regular follow-up appointments with the healthcare provider are essential to monitor the response to treatment and manage any potential side effects.
• Adherence: It’s crucial to take the medication exactly as prescribed by the healthcare provider. Missing doses or altering the prescribed schedule could affect the effectiveness of the treatment.

It’s important to note that the information provided here is general, and individual patient circumstances may vary. Patients should always consult their healthcare provider or pharmacist for specific instructions tailored to their situation.

Other uses for this medicine

Tabrecta (capmatinib) is primarily indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) with specific genetic mutations, specifically those that result in mesenchymal-epithelial transition (MET) exon 14 skipping. It is important to note that medications may be prescribed for uses not listed in the approved professional labeling (off-label uses) based on the clinical judgment of the healthcare provider.

What special precautions should I follow?

Regarding special precautions for Tabrecta, it’s crucial to follow the healthcare provider’s instructions and adhere to the recommended guidelines. Here are some general precautions associated with Tabrecta:

• Medical History: Inform your healthcare provider about your complete medical history, including any pre-existing conditions, allergies, or medications you are currently taking. This information helps in assessing the overall suitability and safety of Tabrecta for your specific situation.
• Liver Function: Tabrecta may affect liver function, so regular monitoring of liver function tests may be required during treatment. Inform your healthcare provider of any signs or symptoms of liver problems, such as jaundice, abdominal pain, or unusual fatigue.
• Interactions with Other Medications: Certain medications or substances may interact with Tabrecta. It’s important to inform your healthcare provider about all prescription and over-the-counter medications, as well as any herbal supplements or vitamins you are taking.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. The potential risks and benefits of using Tabrecta during pregnancy or breastfeeding should be carefully considered.
• Adverse Reactions: Be aware of potential side effects and report any unusual or severe reactions to your healthcare provider promptly. Side effects may include nausea, vomiting, fatigue, difficulty breathing, and changes in liver function tests.
• Dose Adjustments: Your healthcare provider may adjust the dose of Tabrecta based on your individual response and any side effects experienced during treatment.

It’s important to remember that individual circumstances can vary, and the information provided here is general. Always consult with your healthcare provider for personalized advice and to stay informed about any updates or changes in recommendations that may have occurred after last update.

What special dietary instructions should I follow?

As of last update, there were no specific dietary restrictions associated with Tabrecta. However, it’s important to follow a balanced and healthy diet as advised by your healthcare provider. If you have concerns about potential interactions between certain foods and Tabrecta, discuss them with your healthcare team.

What should I do if I forget a dose?

If you forget to take a dose of Tabrecta, the general recommendation is to take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose. In that case, you should skip the missed dose and resume your regular dosing schedule. Do not double up on doses to make up for a missed one.

What side effects can this medication cause?

Tabrecta (capmatinib) can cause various side effects, and it’s important to be aware of these potential reactions. However, it’s crucial to note that not everyone will experience the same side effects, and some individuals may not experience any side effects at all. Additionally, the severity of side effects can vary from person to person. If you are prescribed Tabrecta, your healthcare provider will monitor your response to the medication and help manage any side effects. Here are some common side effects associated with Tabrecta:

• Gastrointestinal Issues:
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain
• Fatigue:
  • Tiredness or weakness
• Edema:
  • Swelling, usually in the legs or hands
• Changes in Liver Function:
  • Elevated liver enzymes (as seen in blood tests)
  • Jaundice (yellowing of the skin or eyes)
• Respiratory Issues:
  • Shortness of breath
  • Cough
• Musculoskeletal Issues:
  • Muscle pain or weakness
  • Joint pain
• Central Nervous System Effects:
  • Headache
  • Dizziness

It’s important to promptly report any unusual or severe symptoms to your healthcare provider. They can provide guidance on managing side effects and may adjust the dose if necessary. In some cases, side effects may lead to dose interruptions or modifications.

This list is not exhaustive, and other side effects may occur. Additionally, information provided here is based on knowledge, and there may have been updates or changes since then. Always consult with your healthcare provider for the most current information and personalized guidance based on your specific health status. If you experience severe or life-threatening side effects, seek immediate medical attention.

What should I know about storage and disposal of this medication?

Storage and Disposal of Tabrecta:

• Storage:
  • Store Tabrecta (capmatinib) at room temperature, away from excessive heat and moisture.
  • Keep the medication in its original container, and make sure the container is tightly closed.
  • Avoid exposing the medication to direct sunlight.
• Disposal:
  • Dispose of Tabrecta according to local regulations and guidelines.
  • Do not flush medications down the toilet unless instructed to do so.
  • Check with your healthcare provider or pharmacist for guidance on proper disposal methods.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms, seek emergency medical attention immediately. Symptoms of overdose may include:

• Severe nausea or vomiting
• Persistent diarrhea
• Unexplained fatigue or weakness
• Signs of liver problems (yellowing of the skin or eyes, dark urine, persistent abdominal pain)

What other information should I know?

• Regular Follow-up: Attend all scheduled follow-up appointments with your healthcare provider to monitor your response to Tabrecta and address any concerns.
• Medication Interactions: Inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medications, herbal supplements, and vitamins.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. The potential risks and benefits of using Tabrecta during pregnancy or breastfeeding should be carefully considered.
• Report Side Effects: Report any side effects or unusual symptoms to your healthcare provider promptly. This includes symptoms that may not be listed in the official prescribing information.
• Dose Adjustments: Your healthcare provider may make adjustments to the dose based on your individual response and any side effects experienced during treatment.
• Compliance: Take Tabrecta exactly as prescribed by your healthcare provider. If you have concerns about the medication or experience difficulties with adherence, discuss them with your healthcare team.
• Lab Tests: Your healthcare provider may order regular lab tests, including liver function tests, to monitor your health during Tabrecta treatment.
• Educational Resources: Ask your healthcare provider or pharmacist for educational resources or written materials about Tabrecta. Understanding the medication can empower you to manage your treatment more effectively.

Always consult with your healthcare provider for personalized advice and the most up-to-date information on Tabrecta. If you have specific questions or concerns, your healthcare team is the best source of guidance based on your individual health status.