Ophthalmic prednisolone reduces the irritation, redness, burning, and swelling of eye inflammation caused by chemicals, heat, radiation, infection, allergy, or foreign bodies in the eye. It sometimes is used after eye surgery. Prednisolone is in a class of medications called steroids. It prevents swelling and redness by changing the way the immune system works.

Ophthalmic prednisolone comes as a solution (liquid) and a suspension (eye drops) to instill in the eye and as an eye ointment to apply to the eye. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use prednisolone eye drops or eye ointment exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Continue to use prednisolone eye drops or eye ointment even if you feel well. Do not stop using prednisolone eye drops or eye ointment without talking to your doctor.

To use the eye drops, follow these instructions:

1. Wash your hands thoroughly with soap and water.
2. Check the label on your bottle to see if you should shake the eye drops before using. Shake the bottle well if the label says that you should
3. Check the dropper tip to make sure that it is not chipped or cracked.
4. Avoid touching the dropper tip against your eye or anything else; eye drops and droppers must be kept clean.
5. While tilting your head back, pull down the lower lid of your eye with your index finger to form a pocket.
6. Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it.
7. Brace the remaining fingers of that hand against your face.
8. While looking up, gently squeeze the dropper so that a single drop falls into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid.
9. Close your eye for 2 to 3 minutes and tip your head down as though looking at the floor. Try not to blink or squeeze your eyelids.
10. Place a finger on the tear duct and apply gentle pressure.
11. Wipe any excess liquid from your face with a tissue.
12. If you are to use more than one drop in the same eye, wait at least 5 minutes before instilling the next drop.
13. Replace and tighten the cap on the dropper bottle. Do not wipe or rinse the dropper tip.
14. Wash your hands to remove any medication.

Toapply the eye ointment, follow these steps:

1. Wash your hands thoroughly with soap and water.
2. Use a mirror or have someone else apply the ointment.
3. Avoid touching the tip of the tube against your eye or anything else. The ointment must be kept clean.
4. Tilt your head forward slightly.
5. Holding the tube between your thumb and index finger, place the tube as near as possible to your eyelid without touching it.
6. Brace the remaining fingers of that hand against your cheek or nose.
7. With the index finger of your other hand, pull the lower lid of your eye down to form a pocket.
8. Place a small amount of ointment into the pocket made by the lower lid and the eye. A 1/2-inch (1.25-centimeter) strip of ointment usually is enough unless otherwise directed by your doctor.
9. Gently close your eyes and keep them closed for 1 to 2 minutes to allow the medication to be absorbed.
10. Replace and tighten the cap right away.
11. Wipe off any excess ointment from your eyelids and lashes with a clean tissue. Wash your hands again.
12. Your vision may be blurry for a short amount of time after using the eye ointment. Wait until you can see normally before you drive or do other activities that require good vision.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before using prednisolone eye drops or eye ointment,

• Tell your doctor and pharmacist if you are allergic to prednisolone or any other drugs.
• Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins.
• Tell your doctor if you have or have ever had glaucoma or diabetes.
• Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using prednisolone eye drops or eye ointment, call your doctor immediately.

Instill or apply the missed dose as soon as you remember it. Use any remaining doses for that day at evenly spaced intervals. However, if you remember a missed dose at the time the next one is due, use only the regularly scheduled dose. Do not instill or apply a double dose to make up for a missed one.

Prednisolone eye drops and eye ointment may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• Temporary eye burning or stinging
• Temporary blurred vision

Some side effects can be serious. If you experience the following symptom, call your doctor immediately:

• Eye pain

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Keep all appointments with your doctor.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

If you still have symptoms of eye irritation after you finish the prednisolone eye drops or eye ointment, call your doctor.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.