Why is this medication prescribed?

Rolapitant is a medication used in combination with other antiemetic drugs to prevent delayed nausea and vomiting associated with chemotherapy. It is often prescribed to adult patients undergoing moderately or highly emetogenic (likely to cause nausea and vomiting) chemotherapy.

Rolapitant belongs to a class of drugs called neurokinin-1 (NK-1) receptor antagonists. It works by blocking the action of substance P, a neurotransmitter involved in nausea and vomiting. By inhibiting substance P, Rolapitant helps to prevent and control nausea and vomiting caused by chemotherapy.

How should this medicine be used?

Rolapitant is a medication used to prevent nausea and vomiting caused by chemotherapy. It is typically prescribed by a healthcare professional, and it’s crucial to follow their instructions and the provided dosing guidelines. Here are general guidelines for the use of Rolapitant:

• Dosage: The typical dose of Rolapitant is often a single oral dose taken about 1 to 2 hours before the start of chemotherapy.
• Administration: Rolapitant is usually taken orally with or without food. It comes in the form of a capsule, and you should swallow it whole with a glass of water. Do not crush, chew, or open the capsule.
• Use with other antiemetic medications: Rolapitant is often used in combination with other antiemetic (anti-nausea) medications as part of a comprehensive approach to prevent chemotherapy-induced nausea and vomiting.
• Follow healthcare provider’s instructions: Always follow the specific instructions provided by your healthcare provider. They will determine the appropriate dosage and schedule based on your individual medical condition, the type of chemotherapy you are receiving, and other factors.
• If a dose is missed: If you miss a dose of Rolapitant, take it as soon as you remember. However, if it’s close to the time of your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses to make up for a missed one.
• Storage: Store Rolapitant at room temperature, away from moisture and heat. Keep it in its original packaging.

Always communicate with your healthcare provider about any concerns or questions you may have regarding the use of Rolapitant. They can provide personalized advice based on your medical history and specific treatment plan. If you experience any side effects or have concerns about the medication, contact your healthcare provider promptly.

Other uses for this medicine

Rolapitant is primarily indicated for preventing chemotherapy-induced nausea and vomiting (CINV). It is not typically used for other conditions. However, medical information can change, and it’s essential to consult with a healthcare professional or refer to the most recent medical literature for updates on the uses of Rolapitant.

What special precautions should I follow?

Regarding special precautions for Rolapitant, here are some general guidelines:

• Allergies: Inform your healthcare provider if you are allergic to Rolapitant or any other medications. This is crucial to avoid potential allergic reactions.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Rolapitant with your healthcare provider. It’s essential to weigh the benefits against potential risks during pregnancy.
• Drug Interactions: Provide a complete list of all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Rolapitant may interact with certain medications, and your healthcare provider needs this information to prevent adverse reactions.
• Liver Function: Rolapitant is metabolized in the liver. If you have liver problems, your healthcare provider may need to adjust the dosage or monitor you more closely.
• Side Effects: Be aware of potential side effects of Rolapitant, including fatigue, hiccups, constipation, and headache. If you experience any unusual or severe side effects, contact your healthcare provider.
• Dosing Instructions: Follow your healthcare provider’s dosing instructions carefully. Take Rolapitant exactly as prescribed, and do not adjust the dosage without consulting your healthcare professional.
• Food Interactions: Rolapitant can be taken with or without food, but it’s essential to follow the specific instructions provided by your healthcare provider.

Always consult with your healthcare provider for personalized advice and information based on your specific medical history and condition. If you have any concerns or questions about Rolapitant, your healthcare provider is the best resource for guidance.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Rolapitant. It can be taken with or without food. However, always follow your healthcare provider’s instructions regarding the timing and administration of the medication.

What should I do if I forget a dose?

If you forget to take a dose of Rolapitant, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

What side effects can this medication cause?

Rolapitant is a medication used to prevent nausea and vomiting caused by chemotherapy. Like any medication, it can cause side effects. It’s important to note that not everyone will experience these side effects, and some people may experience only mild effects. Common side effects of Rolapitant may include:

• Fatigue: Feeling tired or having a lack of energy.
• Headache: Pain or discomfort in the head.
• Dizziness: Feeling lightheaded or unsteady.
• Constipation: Difficulty in passing stools or infrequent bowel movements.
• Hiccups: Involuntary contractions of the diaphragm, resulting in a sudden intake of breath.

It’s essential to inform your healthcare provider if you experience any side effects, especially if they are severe or persistent. Additionally, if you notice any signs of an allergic reaction (such as rash, itching, swelling, severe dizziness, or difficulty breathing), seek medical attention immediately.

This list is not exhaustive, and individual responses to medications can vary. Always follow your healthcare provider’s instructions and report any concerns or side effects promptly. If you have specific questions or concerns about Rolapitant, it’s recommended to consult with your healthcare provider or pharmacist for personalized information based on your medical history and current health status.

What should I know about storage and disposal of this medication?

Storage and Disposal of Rolapitant:

• Store Rolapitant at room temperature, away from moisture and heat.
• Keep the medication in its original packaging, and store it out of reach of children.
• Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Rolapitant when it is expired or no longer needed.
• Consult with your pharmacist or local waste disposal company on how to safely dispose of unused or expired medications.

In case of emergency/overdose

In case of an emergency or overdose, seek medical attention immediately. The symptoms of overdose may include severe dizziness or fainting. It’s important to go to the nearest emergency room or contact your local poison control center.

What other information should I know?

• Inform all healthcare providers about the medications you are currently taking, including Rolapitant, to prevent potential drug interactions.
• Attend all scheduled appointments with your healthcare provider to monitor your response to treatment and address any concerns.
• Do not change the dosage or stop taking Rolapitant without consulting your healthcare provider.
• If you are scheduled to undergo surgery or any medical procedures, inform your healthcare provider that you are taking Rolapitant.

Always follow your healthcare provider’s instructions and guidelines. If you have any questions or concerns about Rolapitant, consult with your healthcare provider or pharmacist for personalized advice based on your medical history and current health status.