Why is this medication prescribed?

Rhofressa (netarsudil ophthalmic solution) is a medication used to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Elevated intraocular pressure is a risk factor for glaucoma, a condition that can lead to optic nerve damage and vision loss if left untreated.

Netarsudil, the active ingredient in Rhopressa, works by inhibiting the Rho kinase enzyme, which plays a role in the regulation of intraocular pressure. By inhibiting this enzyme, Rhopressa helps to increase the outflow of aqueous humor (fluid inside the eye), thereby reducing intraocular pressure.

How should this medicine be used?

As for how Rhopressa should be used, it is typically applied topically to the affected eye(s). The usual recommended dosage is one drop in the affected eye(s) once daily in the evening. It’s important to follow your doctor’s instructions regarding the use of Rhopressa and not to exceed the prescribed dosage.

Here are general steps on how to use Rhopressa eye drops:

• Wash your hands thoroughly before handling the eye drops.
• Shake the bottle well before using to ensure proper mixing of the medication.
• Tilt your head back slightly and pull down your lower eyelid to create a small pocket.
• Hold the dropper above the eye and squeeze the prescribed number of drops into the pocket formed by the lower eyelid.
• Close your eyes gently and press a finger against the inner corner of the eye for about 1-2 minutes. This helps prevent the medication from draining into the tear duct and being absorbed into the bloodstream.
• If you are using Rhopressa in both eyes, repeat the process for the other eye.

It’s important to use Rhopressa regularly as prescribed by your doctor. If you miss a dose, use it as soon as you remember, unless it’s almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

As with any medication, it’s essential to inform your doctor about your medical history, any other medications you are taking, and any pre-existing eye conditions before starting Rhopressa. Additionally, regular follow-up appointments with your eye care professional are crucial to monitor the effectiveness of the treatment and address any potential side effects.

Other uses for this medicine

Rhopressa (netarsudil ophthalmic solution) is primarily indicated for the treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It is not typically prescribed for other medical conditions. However, it’s important to note that new information or uses for medications may have emerged since my last update.

What special precautions should I follow?

Special precautions and considerations when using Rhopressa include:

• Allergies: Inform your doctor if you are allergic to netarsudil or any other ingredients in Rhopressa.
• Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The safety of Rhopressa during pregnancy or breastfeeding has not been established, and your doctor will weigh the potential risks and benefits.
• Medical History: Provide your doctor with a comprehensive medical history, including any eye conditions, allergies, or other health issues. Certain eye conditions may affect the suitability of Rhopressa for your treatment.
• Contact Lenses: If you wear contact lenses, it’s advisable to remove them before applying Rhopressa. You can reinsert the lenses 15 minutes after using the eye drops.
• Systemic Absorption: Rhopressa is an eye drop medication, but a small amount can be absorbed into the bloodstream. This could potentially lead to systemic side effects. Inform your doctor about any systemic conditions you have, especially cardiovascular issues.
• Interactions with Other Medications: Inform your doctor about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Rhopressa.
• Eye Reactions: Rhopressa may cause eye redness, irritation, or other ocular reactions. If you experience any persistent or severe side effects, contact your doctor.
• Special Populations: The safety and efficacy of Rhopressa in pediatric patients have not been established. It is primarily indicated for use in adults.
• Driving and Operating Machinery: Rhopressa may cause blurred vision or other visual disturbances. Avoid driving or operating heavy machinery until you are certain of how the medication affects your vision.

Always follow your doctor’s instructions and recommendations regarding the use of Rhopressa. If you have any concerns or experience unexpected side effects, contact your healthcare provider promptly. Keep in mind that information on medications may have evolved since my last update, and it’s crucial to consult with a healthcare professional for the latest guidance.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are no specific dietary restrictions associated with Rhopressa. However, it’s always a good idea to maintain a healthy and balanced diet to support overall well-being.

What should I do if I forget a dose?

If you forget to take a dose of Rhopressa, follow these general guidelines:

• Missed Dose: If you miss a dose, use it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Double Dosing: Do not use extra doses to make up for a missed one. Using more than the prescribed amount can increase the risk of side effects without providing additional benefits.
• Regular Schedule: Resume your regular dosing schedule. It’s important to be consistent with the timing of your Rhopressa doses to maintain the effectiveness of the medication.

What side effects can this medication cause?

Rhopressa (netarsudil ophthalmic solution) may cause side effects, and it’s essential to be aware of them. Common side effects may include:

• Eye Redness: Redness of the eye is a common side effect and may occur shortly after using Rhopressa.
• Instillation Site Pain: Some people may experience discomfort or pain at the site where the eye drops are instilled.
• Corneal Verticillata: This refers to the appearance of corneal deposits that may look like fine, brown or grayish streaks. These deposits are generally benign and do not affect vision.
• Corneal Staining: Rhopressa may cause corneal staining, which is the presence of fluorescein dye on the cornea. This is typically assessed by eye care professionals during eye examinations.
• Conjunctival Hyperemia: Increased blood flow to the conjunctiva (the clear membrane covering the white part of the eye) can result in conjunctival hyperemia or eye redness.
• Blurred Vision: Rhopressa may cause temporary blurred vision, and patients are advised to exercise caution, especially while driving or operating machinery.
• Foreign Body Sensation: Some individuals may experience a sensation of having a foreign body in the eye.

It’s important to note that not everyone will experience these side effects, and some people may not experience any side effects at all. Additionally, the severity and duration of side effects can vary among individuals.

If you experience persistent or severe side effects, it’s crucial to contact your healthcare provider promptly. Serious side effects are rare, but they can include allergic reactions or other eye problems that require immediate medical attention.

This list of side effects is not exhaustive, and other side effects may occur. Always follow your doctor’s advice and report any unusual or bothersome symptoms during your treatment with Rhopressa. If you have specific concerns about your eye health or the use of Rhopressa, discuss them with your eye care professional or healthcare provider for personalized guidance.

What should I know about storage and disposal of this medication?

Storage and Disposal of Rhopressa:

• Storage:
  • Store Rhopressa at room temperature between 15°C to 25°C (59°F to 77°F).
  • Keep the bottle tightly closed when not in use.
  • Protect the medication from light.
• Disposal:
  • Discard any unused or expired Rhopressa in accordance with local regulations.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard Rhopressa in a designated medication disposal container or through a take-back program.

In case of emergency/overdose

• In the case of accidental ingestion of Rhopressa or if you suspect an overdose, seek emergency medical attention or contact a poison control center immediately.
• Overdose symptoms may include severe eye irritation, increased redness, and other adverse reactions. Do not attempt to self-treat an overdose; professional medical help is crucial.

What other information should I know?

• Follow-up Appointments: Attend all scheduled follow-up appointments with your eye care professional. Regular check-ups are essential to monitor the effectiveness of the treatment and to address any potential issues.
• Inform Healthcare Providers: Inform all healthcare providers involved in your care, including dentists and surgeons, about your use of Rhopressa. The medication can have systemic effects, and healthcare providers should be aware of your current medications.
• Avoid Contamination: Do not touch the tip of the Rhopressa dropper to any surface, including the eye, to prevent contamination. Contaminated eye drops may lead to eye infections.
• Contact Lenses: Remove contact lenses before using Rhopressa. You can reinsert the lenses 15 minutes after applying the eye drops.
• Systemic Absorption: Be aware that a small amount of Rhopressa may be absorbed into the bloodstream. Inform your doctor about any systemic conditions or other medications you are taking.
• Driving and Machinery Operation: Rhopressa may cause temporary blurred vision. Avoid activities that require clear vision until you are sure about how the medication affects your eyesight.
• Allergic Reactions: Seek medical attention if you experience signs of an allergic reaction, such as itching, swelling, severe dizziness, or difficulty breathing.

Always adhere to your healthcare provider’s instructions and recommendations regarding the use of Rhopressa. If you have any concerns or questions about your medication, consult with your eye care professional or healthcare provider for personalized guidance.