PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Refissa (Generic Tretinoin Topical)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.


Why is this medication prescribed?

Refissa is a prescription medication that contains tretinoin, which is a form of vitamin A. Tretinoin is commonly used topically to treat acne and to reduce the appearance of fine wrinkles and mottled skin discoloration.

Here are some common uses and guidelines for using Refissa:

  • Acne: Tretinoin is often prescribed for the treatment of acne. It works by increasing the turnover of skin cells, preventing the formation of new acne lesions.
  • Wrinkles and Skin Discoloration: Tretinoin is also used to improve the appearance of fine wrinkles and to lighten dark spots on the skin.

How should this medicine be used?

Here are some general guidelines for using Refissa Medicine:

  • Prescription Only: Refissa is available only with a prescription, so it should be used under the supervision of a healthcare provider.
  • Application Frequency: The frequency of application can vary based on the individual and the condition being treated. Typically, it is applied once daily in the evening.
  • Clean the Skin: Before applying Refissa, the skin should be clean and dry.
  • Pea-sized Amount: A pea-sized amount of Refissa is usually sufficient to cover the entire face.
  • Avoid Sensitive Areas: Avoid applying Refissa to areas around the eyes, mouth, and other sensitive areas unless directed by your healthcare provider.
  • Sun Protection: Tretinoin can increase sensitivity to sunlight. It is important to use sunscreen and protective clothing during sun exposure to prevent sunburn.
  • Patience and Consistency: Results may not be immediately noticeable, and it may take several weeks to see improvement. Consistent use as prescribed is important for optimal results.
  • Consultation with Healthcare Provider: If there are any concerns or side effects, it’s crucial to consult with the prescribing healthcare provider.

Keep in mind that these guidelines are general, and individual instructions may vary. It’s essential to follow the specific instructions provided by your healthcare provider when using Refissa or any other prescription medication. Additionally, there may have been updates or changes to medical guidelines, so it’s always best to consult with a healthcare professional for the most current information.

Other uses for this medicine

Tretinoin, the active ingredient in Refissa, is primarily used for the treatment of acne and the reduction of fine wrinkles and skin discoloration. However, it’s important to note that healthcare providers may prescribe medications off-label for conditions not specifically approved by regulatory authorities. Off-label use refers to the use of a medication for a purpose other than its approved indications. If your healthcare provider has prescribed Refissa for a specific condition, they will have considered the potential benefits and risks for your individual case.

What special precautions should I follow?

Special Precautions for Refissa:

  • Pregnancy and Breastfeeding: Tretinoin may be harmful to a developing fetus, so it’s important to inform your healthcare provider if you are pregnant or planning to become pregnant. If you are breastfeeding, discuss the potential risks and benefits with your healthcare provider.
  • Sun Exposure: Tretinoin can increase sensitivity to sunlight. It is essential to use sunscreen and protective clothing to avoid sunburn. Limit sun exposure, and avoid tanning beds.
  • Skin Irritation: Tretinoin can cause skin irritation, including redness, peeling, and dryness. If irritation is severe or persistent, contact your healthcare provider.
  • Avoid Sensitive Areas: Refissa should not be applied to areas around the eyes, mouth, or mucous membranes unless specifically directed by your healthcare provider.
  • Other Topical Medications: Avoid using other topical medications or products that may cause irritation, unless your healthcare provider advises otherwise.
  • Consultation with Healthcare Provider: Before using Refissa, inform your healthcare provider about your medical history, including any allergies, current medications, or skin conditions.
  • Gradual Introduction: If you are new to tretinoin, your healthcare provider may recommend a gradual introduction to allow your skin to acclimate to the medication.
  • Avoid Waxing: Avoid waxing or skin procedures that may cause irritation while using Refissa.
  • Children: The safety and effectiveness of Refissa in children have not been established, and its use in this population should be determined by a healthcare provider.

Always follow the specific instructions provided by your healthcare provider and the information on the medication label. If you have any questions or concerns about the use of Refissa, it’s crucial to discuss them with your healthcare provider for personalized guidance based on your medical history and condition.

What special dietary instructions should I follow?

There are typically no specific dietary restrictions associated with the use of Refissa. Tretinoin is a topical medication, and its effects are primarily localized to the skin. However, it’s essential to maintain a healthy diet and lifestyle for overall well-being.

What should I do if I forget a dose?

If you forget to apply a dose of Refissa, apply it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply extra medication to make up for a missed dose.

What side effects can this medication cause?

Refissa, which contains tretinoin, may cause side effects. It’s important to note that not everyone will experience these side effects, and their severity can vary. Common side effects are often temporary and may diminish as your skin adjusts to the medication. However, if you experience persistent or severe side effects, it’s essential to contact your healthcare provider. Some potential side effects of Refissa (tretinoin) may include:

  • Skin Irritation: This is a common side effect and may include redness, peeling, dryness, and a sensation of warmth. It’s advisable to start with a lower concentration of tretinoin and gradually increase as your skin becomes accustomed to the medication.
  • Sun Sensitivity: Tretinoin can increase sensitivity to sunlight. It is crucial to use sunscreen and protective clothing to avoid sunburn. Limit sun exposure, and avoid tanning beds.
  • Stinging or Burning Sensation: Some individuals may experience a stinging or burning sensation upon application of Refissa.
  • Changes in Skin Color: Tretinoin may cause changes in skin pigmentation, especially in individuals with darker skin tones.
  • Itching or Swelling: In some cases, individuals may experience itching or swelling of the skin.
  • Blistering or Crusting: Severe skin reactions such as blistering or crusting are rare but should be reported to your healthcare provider immediately.
  • Eye Irritation: If Refissa comes into contact with the eyes, it can cause irritation. Avoid applying the medication to the eye area.
  • Allergic Reactions: While uncommon, some individuals may be allergic to tretinoin, leading to symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing. Seek medical attention if you experience signs of an allergic reaction.

It’s important to follow your healthcare provider’s instructions for the use of Refissa and report any side effects promptly. They may adjust the dosage or recommend additional measures to manage side effects. If you have concerns about the side effects or if you experience any unusual symptoms, contact your healthcare provider for guidance. Additionally, the information provided here is based on knowledge, and there may be updates or new information. Always consult with your healthcare provider for the most current advice.

What should I know about storage and disposal of this medication?

Storage and Disposal of Refissa:

  • Storage:
    • Store Refissa at room temperature, away from moisture and heat.
    • Keep the medication container tightly closed.
    • Avoid exposing Refissa to extreme temperatures.
  • Disposal:
    • Follow local regulations or guidelines for the proper disposal of expired or unused medications.
    • Do not flush Refissa down the toilet or pour it into a drain unless instructed to do so.

In case of emergency/overdose

In case of accidental ingestion or overdose of Refissa, contact your local poison control center or seek emergency medical attention immediately. Overdose symptoms may include severe skin irritation, swelling, or other serious reactions.

What other information should I know?

  • Follow Healthcare Provider’s Instructions: Use Refissa exactly as prescribed by your healthcare provider. Follow the recommended dosage and application instructions.
  • Avoid Sun Exposure: Tretinoin can increase sensitivity to sunlight. Use sunscreen and protective clothing to prevent sunburn. Limit sun exposure, and avoid tanning beds.
  • Inform Healthcare Provider: Inform your healthcare provider about all the medications, including over-the-counter drugs and supplements, that you are currently taking.
  • Avoid Certain Products: Avoid using abrasive or irritating skincare products while using Refissa unless directed by your healthcare provider.
  • Inform About Medical Conditions: Inform your healthcare provider about any pre-existing skin conditions, allergies, or other medical conditions.
  • Expect Initial Irritation: Initial use of tretinoin may cause skin irritation. This is often temporary and may improve with continued use.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Refissa with your healthcare provider.
  • Regular Follow-ups: Attend follow-up appointments with your healthcare provider to monitor progress and address any concerns.
  • Keep Out of Reach of Children: Keep Refissa out of the reach of children and pets.

Always consult with your healthcare provider or pharmacist if you have specific questions about the storage, disposal, or use of Refissa. The information provided here is based on knowledge, and there may be updates or new information.

Copyright © 2023 PrescriptionGiant.com