Why is this medication prescribed?

The disorder known as amyotrophic lateral sclerosis, sometimes known as Lou Gehrig’s disease, is treated with edaravone. In ALS, the nerves that regulate muscular action gradually die, causing the muscles to weaken and shrink. Antioxidants are the class of drugs that includes edaravone. It might be effective in reducing the nerve damage brought on by the escalating symptoms of ALS.

How should this medicine be used?

Edaravone is administered orally or via a feeding tube as a suspension, or liquid. Usually, it is taken first thing in the morning, empty-handed. If you have a high-fat meal the previous evening (800-1000 calories, 50% fat), you shouldn’t take edavarone for at least 8 hours afterward. It is recommended to wait at least 4 hours after eating a low-fat meal (400-500 calories, 25% fat) before taking edavarone. You should wait at least two hours before taking edavarone if you have consumed a meal supplement, such as a protein drink (250 calories). It is recommended that you refrain from eating or drinking anything other than water for at least an hour after taking edaravone. Take edaravone daily at approximately the same time. Make sure you carefully follow the instructions on the label of your prescription, and ask your pharmacist or doctor to clarify anything you are unsure about. Follow the directions on the edaravone exactly. Take it exactly as suggested by your doctor; do not take it more or less frequently.

Initially, for the first 14 days of a 28-day cycle, it is typically administered once daily. It is administered once daily for the first ten days of a 28-day cycle following the initial cycle. Depending on how your body reacts to edaravone, your doctor will determine how often you should take it.

Make sure to shake the bottle vigorously for at least thirty seconds before opening Edaravone. Only the accompanying oral syringe should be used to measure the dosage of edaravone.  Additionally, edaterone oral suspension can be inserted into silicone or PVC nasogastric (NG) or percutaneous endoscopic gastrostomy (PEG) tubes. Using a catheter-tip syringe, flush the feeding tube with at least 1 ounce (30 mL) of water following the administration of edaravone.

It’s important for patients to follow their healthcare provider’s instructions carefully and attend all scheduled appointments for Radicava infusions. Any concerns or questions about the treatment should be discussed with the healthcare team.

Other uses for this medicine

As of last  update, Edaravone is primarily used for the treatment of amyotrophic lateral sclerosis (ALS). It is not widely prescribed for other conditions. However, ongoing research and clinical trials may explore potential alternative uses for the medication.

What special precautions should I follow?

Special precautions and considerations for Edaravone Oral use include:

• If you have an allergy to sodium bisulfite, edaravone, any other drug, or any of the ingredients in edaravone suspension, let your doctor and pharmacist know. Get an ingredient list from your pharmacist.
• Inform your physician and pharmacist of all other prescription and over-the-counter drugs, vitamins, and dietary supplements that you now take or intend to use. Your doctor might need to carefully monitor you for any negative effects or adjust the dosages of your medications.
• Inform your physician if you now have asthma or have previously had it.
• Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Dial your doctor if you become pregnant while using edaravone.

As medical information and guidelines may change, it is crucial to consult with your healthcare provider or pharmacist for the most current information and recommendations regarding Edaravone Oral. They can provide personalized advice based on your health status and any recent updates in medical literature.

What special dietary instructions should I follow?

As of last update, there were no specific dietary instructions associated with Edaravone Oral. However, it is essential to maintain a balanced and healthy diet as recommended by your healthcare provider.

What should I do if I forget a dose?

If you miss a dose, contact your healthcare provider for guidance. In general, you should not double up on the next dose to make up for a missed one without consulting your healthcare provider.

What side effects can this medication cause?

Edaravone Oral may cause side effects, and it’s important to be aware of potential reactions. Common side effects and adverse reactions associated with Edaravone Oral include:

• Bruising
• Difficulty walking
• Headache
• Red, itchy, or scaly rash

There may be dangerous negative effects. If you see any of these signs, get emergency care or give your doctor a call right away:

• Difficulty breathing, chest tightness, wheezing, and coughing (especially in people with asthma)

This list is not exhaustive, and the information provided here is based on knowledge. New information may have emerged since that time, so it’s always advisable to consult with your healthcare provider or refer to the most recent medical literature for the latest details on medication side effects.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage: Follow the storage instructions provided by the pharmacist or on the medication label. Store Edaravone in a cool, dry place away from direct sunlight and heat.
• Disposal: Dispose of unused or expired medications according to local regulations and guidelines. Do not flush medications down the toilet unless instructed to do so. Contact your local pharmacy or healthcare provider for guidance on proper disposal.

In case of emergency/overdose

In case of emergency or overdose, seek immediate medical attention. If you suspect an overdose or experience severe side effects, contact your local poison control center or emergency room. Be prepared to provide information about the medication and the amount ingested.

What other information should I know?

• Regular Check-ups: Attend scheduled appointments with your healthcare provider for regular check-ups and monitoring. They will assess the effectiveness of the treatment and address any concerns or side effects.
• Medication Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking to prevent potential interactions.
• Follow Instructions: Follow your healthcare provider’s instructions carefully regarding the dosage, schedule, and any other specific guidance related to Edaravone.
• Allergies: If you are allergic to Edaravone or any of its components, inform your healthcare provider immediately.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of Edaravone with your healthcare provider.

As information and guidelines may change, it is crucial to consult with your healthcare provider or pharmacist for the most up-to-date advice based on your current situation and any recent updates in medical guidelines.