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Primaxin IM (Imipenem/Cilastatin) – 500mg 5 Vials

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Imipenem; Cilastatin injection

What is imipenem/cilastatin
IMIPENEM; CILASTATIN (Primaxin®) is an
antibiotic. Imipenem kills or stops the growth of
bacteria that cause severe infections. Cilastatin is
added to make imipenem work better. Imipenem-cilastatin treats many kinds of infections
including those of the skin, bone, heart, blood, stomach, lungs, sinuses, and
kidneys. It also treats certain infections in women (pelvic infections).
Generic imipenem-cilastatin injections are not yet available.

What should I tell my health care
provider before I take this medicine?
They need to know if you have any of these conditions:
•head injury
•kidney disease
•seizure disorder
•other chronic illness
•an unusual or allergic reaction to imipenem, penicillins, cephalosporin antibiotics, or other medicines,
foods, dyes, or preservatives
•pregnant or trying to get pregnant

How should I use this medicine?
Imipenem/cilastatin is for injection into a muscle or
infusion into a vein. Imipenem/cilastatin is usually
given in a hospital or clinic for severe infections. If you are to give
yourself imipenem/cilastatin at home, follow the
directions on the prescription label. Finish the full course prescribed by your
prescriber or health care professional even if you think your condition is
better. Do not stop using except on your prescriber’s
advice. Make sure you understand how to store, mix and give yourself imipenem/cilastatin. Ask your prescriber or health care
professional if you have any questions.

Contact your pediatrician or health care professional regarding the use of this
medicine in children. Special care may be needed.

What if I miss a dose?
If you miss a dose, use it as soon as you can. If it is almost time for your
next dose, use only that dose. Do not use double or extra doses.

What drug(s) may interact with imipenem-cilastatin?

Tell your prescriber or health care professional about all other medicines you
are taking, including non-prescription medicines, nutritional supplements, or
herbal products. Also tell your prescriber or health care professional if you
are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you
use illegal drugs. These may affect the way your medicine works. Check with
your health care professional before stopping or starting any of your

What side effects may I notice
from receiving imipenem-cilastatin?
Side effects that you should report to your prescriber or health care
professional as soon as possible:
Rare or uncommon:
•difficulty breathing, wheezing
•fever or chills, sore throat
•redness, blistering, peeling or loosening of the skin, including inside
the mouth
•severe or watery diarrhea
•skin rash, itching
•twitching or shaking of hands or feet
More common:
•pain, swelling and irritation at the injection site (especially
following deep shots)

Side effects that usually do not require medical attention (report to your prescriber
or health care professional if they continue or are bothersome):
•nausea, vomiting
•too much saliva in the mouth

What should I watch for while
taking imipenem-cilastatin?
Tell your prescriber or health care professional if your symptoms do not begin
to improve in a few days.

If you get severe or watery diarrhea, do not treat yourself. Call your
prescriber or health care professional for advice.

Where can I keep my medicine?
Imipenem-cilastatin is usually given in a hospital.
You may be given imipenem-cilastatin to take home to
complete your treatment. If you are given this medicine to take at home, store
at room temperature or as directed until it is time to mix the medicine. Make
sure you understand how to store, mix and give yourself imipenem-cilastatin;
ask your prescriber or health care professional if you have any questions. Keep
medicine out of reach of children.


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