Why is this medication prescribed?

Plenvu is a prescription medication used for bowel cleansing in preparation for colonoscopy procedures. It helps to clear the colon of stool so that healthcare professionals can have a clear view of the colon during the examination. Colonoscopy is a procedure commonly performed to screen for colorectal cancer, investigate gastrointestinal symptoms, or monitor and manage certain gastrointestinal conditions.

How should this medicine be used?

Here’s a general guide on how Plenvu is typically used, but it’s important to follow the specific instructions provided by your healthcare provider:

• Prescription and Instructions: Plenvu is available only by prescription, and your healthcare provider will provide you with specific instructions on when and how to take it. Follow these instructions carefully.
• Preparation: Usually, Plenvu is taken the day before your scheduled colonoscopy. You will need to follow a clear liquid diet for at least the day before the procedure. Clear liquids may include water, clear broths, sports drinks without red or purple dye, and other approved clear liquids.
• Dosing: Plenvu comes in a split-dose regimen, which means you’ll take a portion of the solution the evening before the colonoscopy and the remaining portion on the morning of the procedure. Typically, you mix the powder with water to prepare the solution.
• Administration: Drink the prepared Plenvu solution according to the schedule provided by your healthcare provider. It’s important to drink plenty of clear liquids alongside the Plenvu solution to stay hydrated.
• Timing: It’s crucial to follow the timing instructions precisely to ensure effective bowel cleansing. Failure to do so may impact the quality of the colonoscopy.
• Monitoring: You may experience bowel movements, possibly diarrhea, as the Plenvu solution works to cleanse the colon. Stay close to bathroom facilities during the preparation period.
• Follow-up Instructions: Your healthcare provider may give you specific instructions about when to stop eating and drinking before the colonoscopy. Follow any additional guidelines provided.

It’s important to inform your healthcare provider of any allergies or medical conditions you have, as well as any medications you are currently taking. They will consider these factors when prescribing and advising on the use of Plenvu.

Always follow your healthcare provider’s instructions closely, and contact them if you have any questions or concerns about the preparation process.

Other uses for this medicine

Plenvu is specifically indicated for bowel cleansing in preparation for colonoscopy and is not intended for other uses. It is important to use the medication only under the guidance and prescription of a healthcare professional for its approved purpose.

What special precautions should I follow?

Special precautions and considerations for using Plenvu include:

• Medical History: Inform your healthcare provider about your complete medical history, especially if you have a history of kidney problems, heart conditions, electrolyte imbalances, or if you are on a low-sodium or low-potassium diet.
• Allergies: Notify your healthcare provider of any allergies you may have, especially if you are allergic to any ingredients in Plenvu.
• Medications: Provide a complete list of all medications, including prescription and over-the-counter drugs, as well as any dietary supplements or herbal products you are taking. Some medications may interact with Plenvu.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Plenvu with your healthcare provider.
• Dehydration: Since Plenvu can cause fluid and electrolyte loss due to its laxative effect, it is important to stay well-hydrated during the bowel preparation process. Make sure to drink plenty of clear fluids as directed by your healthcare provider.
• Monitoring: Keep an eye on your fluid intake, and be aware of signs of dehydration, such as dizziness, lightheadedness, or decreased urine output. Seek medical attention if you experience severe dehydration symptoms.
• Pre-existing Conditions: If you have certain medical conditions, such as severe gastrointestinal disorders or conditions that may increase the risk of fluid and electrolyte imbalances, your healthcare provider will consider these factors before prescribing Plenvu.

Always follow your healthcare provider’s instructions precisely, and contact them if you have any questions, concerns, or experience unexpected side effects. It’s crucial to undergo the prescribed bowel preparation process for colonoscopy to ensure an accurate and thorough examination of the colon.

What special dietary instructions should I follow?

• Clear Liquid Diet: Typically, a clear liquid diet is recommended in the day(s) leading up to the colonoscopy. Approved clear liquids may include water, clear broths, sports drinks without red or purple dye, and similar clear fluids.
• Avoid Certain Foods and Beverages: Your healthcare provider may provide specific guidelines on foods and beverages to avoid during the preparation period.

What should I do if I forget a dose?

If you forget a dose of Plenvu:

• Contact Your Healthcare Provider: If you forget a dose of Plenvu or have difficulty following the prescribed regimen, contact your healthcare provider promptly. They can provide guidance on whether you should continue with the prescribed schedule or if any adjustments are necessary.
• Do Not Double Dose: Do not take a double dose to make up for a missed one. Taking more than the prescribed amount can lead to an increased risk of side effects and complications.
• Follow Provider’s Instructions: Your healthcare provider will provide guidance on how to proceed if a dose is missed. It’s crucial to communicate with them to ensure the effectiveness of the bowel preparation.

What side effects can this medication cause?

Plenvu, like any medication, can cause side effects. It’s important to note that not everyone will experience these side effects, and some individuals may not experience any side effects at all. Common side effects of Plenvu may include:

• Nausea: Feeling an urge to vomit or discomfort in the stomach.
• Abdominal Pain or Discomfort: Pain or discomfort in the abdominal area.
• Vomiting: The act of forcefully expelling stomach contents through the mouth.
• Bloating: Feeling of fullness or tightness in the abdomen due to gas or fluid accumulation.
• Dizziness: Feeling lightheaded or unsteady.
• Headache: Pain or discomfort in the head.
• Fatigue: A feeling of tiredness or lack of energy.
• Dehydration: In rare cases, excessive fluid loss may lead to dehydration, which can manifest as increased thirst, dry mouth, dark urine, and decreased urine output.
• Electrolyte Imbalance: In some cases, the use of bowel preparation solutions like Plenvu can lead to imbalances in electrolytes such as potassium and sodium.

It’s important to contact your healthcare provider if you experience severe or persistent side effects, or if you have any concerns about your well-being during the bowel preparation process. Additionally, let your healthcare provider know if you have a history of certain medical conditions, as some individuals may be at a higher risk of certain side effects.

In rare cases, some individuals may have an allergic reaction to Plenvu. Seek immediate medical attention if you experience symptoms of a severe allergic reaction, such as difficulty breathing, swelling of the face or throat, or severe rash.

Always follow your healthcare provider’s instructions carefully, and communicate openly with them about any concerns or side effects you may be experiencing. They can provide guidance and adjust your treatment plan if necessary.

What should I know about storage and disposal of this medication?

Storage and Disposal of Plenvu:

• Storage:
  • Store Plenvu at room temperature, away from excessive heat and moisture.
  • Keep it in its original packaging to protect it from light.
  • Do not freeze the product.
• Disposal:
  • Dispose of Plenvu according to local regulations and guidelines.
  • Do not flush medications down the toilet or pour them into drains unless instructed to do so.
  • If you are unsure about how to dispose of Plenvu, consult with your pharmacist or healthcare provider.

In case of emergency/overdose

• Seek Medical Attention: In case of an overdose or if you experience severe symptoms, seek immediate medical attention or contact your local poison control center. Symptoms of overdose may include severe dehydration, electrolyte imbalances, and persistent severe side effects.
• Poison Control: In the United States, you can contact the Poison Control Center at 1-800-222-1222 for guidance on overdose management.

What other information should I know?

• Follow Instructions: Adhere to your healthcare provider’s instructions for using Plenvu precisely. This includes dosing, timing, and dietary restrictions.
• Inform Healthcare Provider: Inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs and supplements.
• Allergies: If you have a known allergy to any of the ingredients in Plenvu, inform your healthcare provider immediately.
• Medical History: Discuss your medical history, especially if you have kidney problems, heart conditions, or other health concerns.
• Stay Hydrated: During the bowel preparation process, stay well-hydrated by drinking the recommended clear liquids as instructed.
• Monitoring: Be vigilant for signs of dehydration, electrolyte imbalances, or severe side effects. Contact your healthcare provider if you have concerns.
• Follow-Up: Attend any follow-up appointments or consultations as scheduled by your healthcare provider.
• Colonoscopy Preparation: Understand the importance of completing the bowel preparation process for a successful and accurate colonoscopy.

Always keep emergency contact information, including your healthcare provider and local poison control center, readily available. If you have any questions or concerns about Plenvu, don’t hesitate to reach out to your healthcare provider for guidance.