Why is this medication prescribed?

Picato (ingenol mebutate) is a prescription medication used topically for the treatment of actinic keratosis (AK). Actinic keratosis is a skin condition characterized by rough, scaly patches or lesions on the skin that result from prolonged sun exposure.

How should this medicine be used?

Picato is available in gel form and is applied directly to the affected skin areas. It works by causing cell death in the targeted skin cells, effectively treating actinic keratosis lesions. The treatment duration and application frequency can vary depending on the specific formulation of Picato and the location of the lesions.

Typically, Picato is applied once daily for a specified number of days, and the treatment course can range from 2 to 3 days for some formulations or up to 3 consecutive days for others. It’s important to follow the specific instructions provided by the prescribing healthcare professional and to apply the medication as directed.

Here are general guidelines on how to use Picato:

• Wash the affected area: Cleanse the skin with a mild soap and water and pat it dry before applying Picato.
• Apply a thin layer: Use the provided applicator or your fingertips to apply a thin layer of Picato gel to the affected area. The amount of gel and the treatment duration will depend on the specific prescription.
• Avoid healthy skin: Be careful to apply Picato only to the areas affected by actinic keratosis. Avoid applying it to healthy skin.
• Wash hands after application: After applying Picato, wash your hands thoroughly to avoid inadvertently transferring the medication to other areas of the body.
• Avoid sunlight: During and after the treatment course, it’s important to protect the treated areas from direct sunlight, as the skin may be more sensitive to UV radiation. Use sunscreen and wear protective clothing.
• Follow-up with healthcare provider: Attend any follow-up appointments scheduled by your healthcare provider to monitor the progress of the treatment and discuss any concerns or side effects.

It’s crucial to use Picato exactly as prescribed by your healthcare provider, and if you experience any unusual or severe side effects, contact your healthcare professional promptly. As with any medication, discuss your medical history, current medications, and any concerns with your healthcare provider before starting Picato treatment.

Other uses for this medicine

Picato (ingenol mebutate) is primarily indicated for the treatment of actinic keratosis (AK), a precancerous skin condition. As of last update, there were no other approved uses for Picato. However, it’s important to note that new information may have emerged since then, and you should consult with a healthcare professional or check the latest medical resources for any updates on the uses of Picato.

What special precautions should I follow?

Regarding special precautions for Picato, here are some general guidelines:

• Prescription Only: Picato is a prescription medication, and it should only be used under the supervision of a healthcare provider who can assess your specific condition and medical history.
• Allergies: Inform your healthcare provider about any known allergies to ingenol mebutate or other ingredients in Picato. This is crucial to avoid potential allergic reactions.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Picato with your healthcare provider. The safety of Picato during pregnancy and breastfeeding is not well-established, and caution may be warranted.
• Children and Elderly: The safety and effectiveness of Picato in children or elderly individuals may not be well-established, so use in these populations should be discussed with a healthcare professional.
• Skin Sensitivity: Picato is applied topically to the skin, and some individuals may experience local skin reactions at the application site, such as redness, itching, swelling, crusting, or peeling. If you have a history of skin sensitivity or other skin conditions, inform your healthcare provider.
• Sun Protection: During and after the treatment with Picato, it’s essential to protect the treated areas from exposure to sunlight. Use sunscreen, wear protective clothing, and limit sun exposure to minimize the risk of adverse reactions.
• Other Medications: Inform your healthcare provider about all the medications, including over-the-counter drugs and herbal supplements, that you are currently taking. Some medications may interact with Picato.
• Follow-up: Attend any follow-up appointments scheduled by your healthcare provider to monitor the progress of the treatment and address any concerns or side effects.

Always follow the specific instructions provided by your healthcare provider and the medication guide that comes with Picato. If you have any questions or concerns about the use of Picato, consult with your healthcare professional for personalized advice.

What special dietary instructions should I follow?

As for special dietary instructions, there are no specific dietary restrictions associated with Picato. However, it’s essential to maintain a healthy and well-balanced diet to support overall well-being.

What should I do if I forget a dose?

If you forget to apply a dose of Picato, follow these general guidelines:

• Missed Dose: If you miss a dose, apply it as soon as you remember.
• Next Dose: If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Double Dose: Do not apply a double dose to make up for a missed one. Applying more than the prescribed amount will not increase the effectiveness of the medication and may increase the risk of side effects.

What side effects can this medication cause?

Picato (ingenol mebutate) can cause side effects, and it’s important to be aware of them and promptly notify your healthcare provider if you experience any unusual or severe symptoms. Common side effects of Picato include local skin reactions at the application site. These reactions are usually temporary and may include:

• Redness: The treated area may become red.
• Itching: Itching or a feeling of irritation at the application site.
• Swelling: Some individuals may experience swelling of the skin.
• Crusting or Peeling: The skin may develop a crust or peel as a part of the treatment process.
• Pain or Burning Sensation: Some people may experience pain or a burning sensation at the application site.

These local skin reactions are typically expected and may indicate that the medication is working to treat actinic keratosis. However, if these reactions are severe, persistent, or causing significant discomfort, it’s important to contact your healthcare provider.

In addition to the common side effects, there can be less common or more severe side effects associated with Picato. These may include:

• Allergic Reactions: Although rare, some individuals may experience an allergic reaction to Picato. Seek medical attention immediately if you develop symptoms such as difficulty breathing, swelling of the face or tongue, or severe rash.
• Eye Irritation: Avoid contact with the eyes, as Picato can cause eye irritation. If accidental eye exposure occurs, rinse the eyes thoroughly with water and seek medical attention if irritation persists.
• Infection: There is a risk of bacterial skin infection, especially if there are open sores or breaks in the skin. If you notice signs of infection, such as increased redness, warmth, swelling, or pus, contact your healthcare provider.

It’s important to follow your healthcare provider’s instructions for Picato use and report any side effects promptly. Your healthcare provider will be able to assess the severity of the reactions and provide guidance on whether to continue or modify the treatment. If you have concerns about the side effects of Picato, discuss them with your healthcare provider for personalized advice.

What should I know about storage and disposal of this medication?

Storage and Disposal of Picato:

Storage:

• Room Temperature: Store Picato at room temperature, away from excessive heat and moisture.
• Keep Container Closed: Keep the container tightly closed when not in use.
• Avoid Freezing: Do not freeze Picato.
• Keep Out of Reach of Children: Store Picato in a location that is out of reach of children and pets.

Disposal:

• Follow Local Regulations: Dispose of Picato according to local regulations for medication disposal. Do not flush it down the toilet unless specifically instructed to do so.
• Unused Medication: If you have unused or expired Picato, consult with your healthcare provider or pharmacist about the proper disposal method.

In case of emergency/overdose

In case of an emergency or if you suspect an overdose of Picato, seek medical attention immediately. Emergency symptoms may include severe skin irritation, difficulty breathing, or other serious reactions. Call your local emergency number or go to the nearest emergency room.

What other information should I know?

• Follow Instructions: Always follow the specific instructions provided by your healthcare provider and the medication guide that comes with Picato.
• Inform Healthcare Provider: Keep your healthcare provider informed about any other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.
• Sun Protection: During and after the treatment with Picato, protect the treated areas from sunlight exposure. Use sunscreen, wear protective clothing, and minimize sun exposure to reduce the risk of adverse reactions.
• Follow-up Appointments: Attend any follow-up appointments scheduled by your healthcare provider to monitor the progress of the treatment and address any concerns or side effects.
• Inform About Allergies: Inform your healthcare provider about any known allergies to ingenol mebutate or other components of Picato.
• Avoid Eye Contact: Avoid contact with the eyes, as Picato can cause eye irritation. If accidental eye exposure occurs, rinse the eyes thoroughly with water and seek medical attention if irritation persists.

Always consult with your healthcare provider or pharmacist if you have specific questions or concerns about Picato. They can provide personalized guidance based on your medical history and current health status.