WARNING

Paxil CR (controlled-release) is a brand name for paroxetine, which is a selective serotonin reuptake inhibitor (SSRI) used to treat conditions such as depression, anxiety disorders, and panic disorder. While Paxil CR can be effective for many individuals, it is important to be aware of potential risks and side effects associated with its use. Here is a brief overview:

• Common Side Effects:
  • Nausea
  • Headache
  • Drowsiness
  • Sweating
  • Nervousness
  • Insomnia
• Serotonin Syndrome: SSRIs like Paxil CR can increase serotonin levels. In rare cases, this can lead to serotonin syndrome, a potentially life-threatening condition characterized by symptoms such as confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
• Withdrawal Symptoms: Abruptly stopping Paxil CR can lead to withdrawal symptoms, including dizziness, nausea, headache, irritability, and electric shock-like sensations. It’s important to taper off the medication under the guidance of a healthcare professional.
• Suicidal Thoughts and Behavior: Like many antidepressants, Paxil CR has been associated with an increased risk of suicidal thoughts and behavior, particularly in young adults and adolescents. Close monitoring is necessary, especially when starting the medication or adjusting the dosage.
• Bleeding Risk: SSRIs, including Paxil CR, may increase the risk of bleeding, especially when combined with other medications that affect blood clotting.
• Bone Health: Long-term use of SSRIs has been linked to a potential risk of bone fractures, particularly in older adults.
• Sexual Side Effects: Some individuals may experience sexual side effects, including decreased libido and difficulty achieving or maintaining an erection.
• Interaction with Other Medications: Paxil CR can interact with other medications, potentially affecting their effectiveness or increasing the risk of side effects.

It is crucial to discuss any concerns or potential side effects with a healthcare provider before starting or discontinuing Paxil CR. They can provide personalized advice based on your medical history and current health status.

Why is this medication prescribed?

Paxil CR (controlled-release) is a medication that contains paroxetine, a selective serotonin reuptake inhibitor (SSRI). It is commonly prescribed for the treatment of various mental health conditions. Here are some reasons why Paxil CR may be prescribed:

• Depression: Paxil CR is approved for the treatment of major depressive disorder (MDD), a condition characterized by persistent feelings of sadness and loss of interest or pleasure.
• Generalized Anxiety Disorder (GAD): It is used to treat GAD, a condition involving excessive worry and anxiety that is difficult to control.
• Social Anxiety Disorder (Social Phobia): Paxil CR may be prescribed for social anxiety disorder, which is an intense fear of being judged or scrutinized in social situations.
• Panic Disorder: It is indicated for the treatment of panic disorder, which involves recurrent, unexpected panic attacks.
• Obsessive-Compulsive Disorder (OCD): Paxil CR is sometimes used to manage symptoms of OCD, a condition characterized by persistent, intrusive thoughts and repetitive behaviors.
• Post-Traumatic Stress Disorder (PTSD): It may be prescribed for individuals with PTSD, a condition that can develop after exposure to a traumatic event.

How should this medicine be used?

The dosage and duration of treatment with Paxil CR depend on the specific condition being treated, the individual’s response to the medication, and other factors. It’s important to follow the prescribing healthcare provider’s instructions and not adjust the dosage without consulting them. Here are the uses of Paxil CR:

• Dosage: Paxil CR is typically taken once daily, usually in the morning. The dosage will be determined by the healthcare provider based on the individual’s condition and response to the medication.
• Swallow Whole: Paxil CR tablets should be swallowed whole and not crushed or chewed. Breaking or crushing the tablet may lead to an increased risk of side effects or a quicker release of the medication.
• Consistency: It is important to take Paxil CR consistently at the same time each day to maintain a steady level of the medication in the bloodstream.
• Food Interactions: Paxil CR can be taken with or without food. However, taking it with food may help reduce the risk of stomach upset.
• Follow Healthcare Provider’s Instructions: Always follow the instructions provided by the prescribing healthcare provider. Do not stop taking Paxil CR abruptly without consulting them, as this may lead to withdrawal symptoms.
• Regular Monitoring: Regular follow-up appointments with the healthcare provider are important to monitor the medication’s effectiveness and address any potential side effects or concerns.

Individuals should inform their healthcare provider about any other medications, supplements, or medical conditions they have, as interactions and contraindications may exist. Additionally, it is essential to report any unusual or severe side effects promptly.

Other uses for this medicine

Some potential off-label uses of Paxil CR may include:

• Premenstrual Dysphoric Disorder (PMDD): Paxil CR may be used to alleviate symptoms of PMDD, a severe form of premenstrual syndrome (PMS) characterized by significant mood disturbances.
• Vasomotor Symptoms of Menopause: In some cases, Paxil CR may be considered to help manage hot flashes associated with menopause.
• Chronic Headaches: There is some evidence suggesting that certain SSRIs, including paroxetine (the active ingredient in Paxil CR), may be beneficial in reducing the frequency and severity of chronic headaches.

What special precautions should I follow?

Special Precautions for Paxil CR:

• Suicidal Thoughts and Behavior: Antidepressants, including Paxil CR, may increase the risk of suicidal thoughts, especially in young adults and adolescents. Close monitoring is crucial, particularly during the early stages of treatment.
• Allergic Reactions: Individuals with a known hypersensitivity to paroxetine or any components of Paxil CR should not use the medication. Allergic reactions can be serious and may include rash, itching, swelling, severe dizziness, or difficulty breathing.
• Serotonin Syndrome: Paxil CR, like other SSRIs, can increase serotonin levels and may lead to serotonin syndrome in rare cases. Symptoms include confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
• Pregnancy and Breastfeeding: Pregnant or breastfeeding individuals should discuss the risks and benefits of Paxil CR with their healthcare provider. The medication may pass into breast milk and could pose risks to a nursing infant.
• Medical Conditions: Inform your healthcare provider about any pre-existing medical conditions, especially liver or kidney problems, bleeding disorders, seizures, or a history of drug abuse.
• Interactions with Other Medications: Paxil CR can interact with other medications, including monoamine oxidase inhibitors (MAOIs), other SSRIs, certain antipsychotics, and certain blood-thinning medications. Inform your healthcare provider about all medications, supplements, and herbal products you are taking.

Always follow your healthcare provider’s instructions, attend regular check-ups, and report any concerning side effects promptly. Do not stop taking Paxil CR or adjust the dosage without consulting your healthcare provider, as sudden discontinuation can lead to withdrawal symptoms.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Paxil CR. However, taking the medication with food may help reduce the risk of stomach upset. It is generally recommended to take Paxil CR with or without food, as directed by your healthcare provider.

What should I do if I forget a dose?

If you miss a dose of Paxil CR, take it as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

What side effects can this medication cause?

Paxil CR (controlled-release), like any medication, may cause side effects. It’s important to note that not everyone will experience these side effects, and the severity can vary. If you are prescribed Paxil CR, your healthcare provider will weigh the potential benefits against the risks based on your individual health profile. Common side effects include:

• Nausea: Feeling sick to your stomach is a common side effect, especially when starting the medication.
• Drowsiness: Paxil CR can cause drowsiness or fatigue, which may affect your ability to concentrate or operate machinery.
• Headache: Some individuals may experience headaches, especially during the initial period of treatment.
• Dry Mouth: A reduction in saliva production can lead to a dry mouth.
• Sweating: Increased sweating, including night sweats, can occur.
• Nervousness: Some people may feel more nervous or anxious.
• Insomnia: Difficulty falling asleep or staying asleep may occur, particularly at the beginning of treatment.
• Dizziness: Feeling lightheaded or dizzy is a possible side effect.
• Weight Changes: Paxil CR may be associated with weight gain or loss.
• Sexual Side Effects: This can include decreased libido, difficulty achieving orgasm, or erectile dysfunction.
• Gastrointestinal Upset: Some individuals may experience gastrointestinal symptoms such as diarrhea or constipation.

It’s important to notify your healthcare provider if you experience any side effects, particularly if they are persistent, severe, or interfere with your daily activities. Additionally, there are some potentially serious side effects associated with Paxil CR that require immediate medical attention:

• Suicidal Thoughts: Some individuals, especially those under the age of 24, may experience an increase in suicidal thoughts, especially at the beginning of treatment.
• Serotonin Syndrome: While rare, this is a potentially life-threatening condition characterized by symptoms such as confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
• Allergic Reactions: Seek medical attention immediately if you experience symptoms of an allergic reaction, including rash, itching, swelling, severe dizziness, or difficulty breathing.
• Withdrawal Symptoms: Abruptly stopping Paxil CR may lead to withdrawal symptoms, including dizziness, nausea, headache, irritability, and electric shock-like sensations. It’s important to taper off the medication under the guidance of a healthcare professional.

Always consult with your healthcare provider for personalized information and guidance regarding the potential side effects of Paxil CR based on your specific health conditions and medical history.

What should I know about storage and disposal of this medication?

Storage and Disposal of Paxil CR:

• Storage:
  • Store Paxil CR at room temperature away from light and moisture.
  • Keep the medication in its original packaging or container.
  • Avoid storing it in the bathroom, as the moisture and humidity can affect the stability of the medication.
  • Keep Paxil CR out of reach of children and pets.
• Disposal:
  • Do not flush Paxil CR down the toilet or pour it down the drain unless instructed to do so.
  • Dispose of the medication properly by using a medicine take-back program or following specific disposal instructions provided by your healthcare provider or local authorities.
  • If no take-back program is available, mix Paxil CR with an undesirable substance (e.g., coffee grounds or cat litter) in a sealed plastic bag and throw it away in the trash.

In case of emergency/overdose

In case of an emergency or suspected overdose of Paxil CR, seek medical attention or contact a poison control center immediately. Overdose symptoms may include:

• Nausea
• Vomiting
• Tremor
• Sweating
• Rapid heartbeat
• Confusion
• Seizures

What other information should I know?

• Follow Healthcare Provider’s Instructions: Always take Paxil CR as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting them.
• Regular Monitoring: Attend scheduled follow-up appointments with your healthcare provider to monitor the medication’s effectiveness and address any concerns or side effects.
• Avoid Alcohol: Limit or avoid alcohol consumption while taking Paxil CR, as alcohol can interact with the medication and increase the risk of side effects.
• Drug Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as Paxil CR can interact with other drugs.
• Inform Other Healthcare Providers: If you are scheduled for surgery or dental procedures, inform the surgeon or dentist that you are taking Paxil CR, as it may interact with anesthesia and other medications used during these procedures.
• Pregnancy and Breastfeeding: Discuss the risks and benefits of Paxil CR with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
• Tapering Off: If discontinuing Paxil CR, do so under the guidance of your healthcare provider to minimize the risk of withdrawal symptoms.
• Medical ID: If relevant, consider wearing a medical ID bracelet or carrying a card indicating that you are taking Paxil CR in case of emergencies.

Always consult with your healthcare provider for personalized guidance and information about Paxil CR based on your individual health status and medical history.