WARNING

Ozempic is a medication used to treat type 2 diabetes. While it can be effective in managing blood sugar levels, like any medication, it comes with potential risks and side effects. Here are some of the risks associated with taking Ozempic:

• Hypoglycemia: Ozempic can lower blood sugar levels, and if it drops too much, it can lead to hypoglycemia (low blood sugar). Symptoms may include dizziness, shakiness, confusion, and sweating.
• Gastrointestinal side effects: Some individuals may experience gastrointestinal issues such as nausea, vomiting, diarrhea, and stomach pain while taking Ozempic.
• Pancreatitis: There have been rare cases of pancreatitis (inflammation of the pancreas) reported with the use of Ozempic. Symptoms may include severe abdominal pain that can radiate to the back, nausea, and vomiting.
• Kidney problems: There have been reports of acute kidney injury in some individuals taking Ozempic. If you experience changes in urination, swelling, or difficulty breathing, it’s important to seek medical attention.
• Thyroid tumors: Studies in rodents have shown an increased risk of thyroid tumors with Ozempic. However, it’s unclear whether this risk applies to humans as well. Regular monitoring of the thyroid is still recommended.
• Allergic reactions: In rare cases, individuals may experience allergic reactions to Ozempic. Symptoms may include rash, itching, dizziness, or difficulty breathing. Immediate medical attention should be sought if these symptoms occur.

It’s important to note that not everyone will experience these risks, and many individuals tolerate Ozempic well. However, it’s crucial to discuss any concerns or potential side effects with your healthcare provider before starting or continuing the medication. They can provide personalized information and guidance based on your specific health condition and medical history.

Why is this medication prescribed?

Ozempic (generic name semaglutide) is prescribed for the treatment of type 2 diabetes. It belongs to a class of medications called glucagon-like peptide-1 receptor agonists (GLP-1 RAs).

Here are the primary reasons why Ozempic is prescribed:

• Blood sugar management: Ozempic helps to lower blood sugar levels in people with type 2 diabetes. It works by mimicking the action of a hormone called GLP-1, which helps regulate blood sugar levels by stimulating insulin secretion, reducing glucose production in the liver, and slowing down the absorption of glucose from the intestines.
• Weight management: In addition to its blood sugar-lowering effects, Ozempic has also been found to promote weight loss. This can be beneficial for individuals with type 2 diabetes who may be overweight or obese, as weight loss can improve insulin sensitivity and overall diabetes control.
• Cardiovascular benefits: Studies have shown that Ozempic can reduce the risk of major adverse cardiovascular events, such as heart attack, stroke, and cardiovascular death, in individuals with type 2 diabetes and established cardiovascular disease.
• Once-weekly dosing: Ozempic is administered as a once-weekly injection, which provides convenience and may improve adherence to treatment compared to medications that require daily dosing.

It’s important to note that the use of Ozempic should be determined by a healthcare professional, who will consider factors such as the individual’s overall health, diabetes management goals, and any other medications they may be taking.

How should this medicine be used?

Ozempic (semaglutide) is available as a pre-filled pen for subcutaneous injection. Here are the general guidelines for its use:

• Dosage: The starting dose of Ozempic is typically 0.25 mg once weekly. After at least four weeks, the dose is usually increased to 0.5 mg once weekly to provide optimal blood sugar control. However, your healthcare provider will determine the appropriate dosage for you based on your individual needs.
• Administration: Ozempic is injected under the skin (subcutaneously) in the abdomen, thigh, or upper arm. It’s important to follow the instructions provided by your healthcare professional on how to properly use the pre-filled pen.
• Timing: Ozempic is usually taken once a week on the same day each week. You can choose a specific day that works best for you, such as every Sunday or every Monday. It’s important to try to maintain a consistent schedule to ensure regular dosing.
• Injection technique: Before injecting, make sure to clean the injection site with an alcohol swab. Pinch a fold of skin and inject the medication at a 90-degree angle into the subcutaneous tissue. Follow the specific instructions provided with the Ozempic pen for detailed steps on proper administration.
• Storage: Ozempic pens should be stored in the refrigerator at a temperature between 36°F and 46°F (2°C and 8°C). Avoid freezing the medication. Once opened, the pen can be kept at room temperature (up to 86°F or 30°C) for up to 56 days. Always check the expiration date and do not use the medication if it has expired.

It’s crucial to consult your healthcare provider for personalized instructions on how to use Ozempic correctly. They can provide you with detailed guidance and address any specific concerns or questions you may have.

Other uses for this medicine

Ozempic (semaglutide) is primarily approved for the treatment of type 2 diabetes. However, it’s important to note that healthcare providers may sometimes prescribe medications off-label, meaning for uses not specifically approved by regulatory authorities. It’s always best to consult with a healthcare professional to determine the appropriate and approved uses of any medication.

What special precautions should I follow?

When using Ozempic, there are several special precautions to consider:

• Hypoglycemia risk: Ozempic can lower blood sugar levels, and when combined with other medications that also lower blood sugar (such as insulin or sulfonylureas), the risk of hypoglycemia increases. Close monitoring of blood sugar levels is important, especially when initiating or adjusting the dose of Ozempic or concomitant medications.
• Pancreatitis: There have been rare reports of pancreatitis (inflammation of the pancreas) with the use of Ozempic. If you experience severe abdominal pain that does not go away or if you develop persistent nausea or vomiting, you should seek immediate medical attention.
• Thyroid tumors: Studies in rodents have shown an increased risk of thyroid tumors with Ozempic. While it’s not known if this risk applies to humans, regular monitoring of the thyroid is recommended. Inform your healthcare provider if you have a history of thyroid cancer or any other thyroid-related conditions.
• Kidney function: Ozempic may cause acute kidney injury or worsen existing kidney problems. If you experience changes in urination, swelling, or difficulty breathing, notify your healthcare provider.
• Allergic reactions: Some individuals may develop allergic reactions to Ozempic. Seek immediate medical attention if you experience symptoms such as rash, itching, difficulty breathing, or severe dizziness.
• Pregnancy and breastfeeding: Ozempic is not recommended for use during pregnancy. It’s important to discuss with your healthcare provider if you are planning to become pregnant or if you become pregnant while using Ozempic. The use of Ozempic while breastfeeding is also not recommended, and alternative options should be considered.

These are just some of the precautions associated with Ozempic. It’s essential to consult with your healthcare provider before starting or continuing the medication to ensure it is safe and appropriate for your specific health condition and medical history.

What special dietary instructions should I follow?

When taking Ozempic (semaglutide), there are no specific dietary restrictions that need to be followed. However, it’s generally advisable to maintain a healthy and balanced diet as recommended by your healthcare provider or a registered dietitian. This includes consuming a variety of nutrient-rich foods, controlling portion sizes, and managing carbohydrate intake to help with blood sugar control.

What should I do if I forget a dose?

If you forget to take a dose of Ozempic, here’s what you should do:

• For weekly dosing: If you miss a scheduled dose, take it as soon as you remember, as long as it is at least three days before your next scheduled dose. If it is less than three days until your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed dose.
• If you are unsure or have questions: If you are unsure about what to do or have any concerns, it’s important to contact your healthcare provider or pharmacist for guidance. They can provide you with specific instructions based on your situation and help ensure the appropriate dosing.

What side effects can this medication cause?

Ozempic (semaglutide) can cause several side effects. It’s important to note that not everyone will experience these side effects, and some individuals may have a different response to the medication. Common side effects of Ozempic include:

• Gastrointestinal effects: The most commonly reported side effects of Ozempic are related to the gastrointestinal system. These may include nausea, vomiting, diarrhea, constipation, stomach pain, and indigestion. These side effects are usually mild to moderate in severity and tend to improve over time.
• Hypoglycemia (low blood sugar): Ozempic can lower blood sugar levels, and if the levels drop too much, hypoglycemia may occur. Symptoms of hypoglycemia include dizziness, shakiness, sweating, confusion, headache, and in severe cases, loss of consciousness or seizures. It’s important to be aware of the signs and symptoms of hypoglycemia and to monitor blood sugar levels regularly.
• Injection site reactions: Some individuals may experience mild injection site reactions, such as redness, swelling, itching, or pain at the injection site. These reactions are typically temporary and resolve on their own.
• Thyroid-related effects: In rare cases, Ozempic may affect the thyroid gland. It may lead to increased calcitonin levels, which can prompt further evaluation for thyroid tumors. Symptoms of thyroid tumors may include a lump or swelling in the neck, difficulty swallowing, or changes in voice. Regular monitoring of the thyroid is recommended.
• Pancreatitis: Although rare, pancreatitis (inflammation of the pancreas) has been reported in individuals taking Ozempic. Symptoms may include severe abdominal pain that can radiate to the back, nausea, and vomiting. If these symptoms occur, immediate medical attention should be sought.
• Allergic reactions: In rare cases, individuals may experience allergic reactions to Ozempic. Signs of an allergic reaction may include rash, itching, hives, swelling, dizziness, or difficulty breathing. If you experience any of these symptoms, seek immediate medical help.

It’s important to discuss any side effects or concerns with your healthcare provider. They can provide guidance, monitor your response to the medication, and determine if any adjustments are needed.

What should I know about storage and disposal of this medication?

• Storage: Unopened Ozempic pens should be stored in the refrigerator at a temperature between 36°F and 46°F (2°C and 8°C). Do not freeze the medication. Protect the pen from light. Once opened, the pen can be stored at room temperature (up to 86°F or 30°C) for up to 56 days.
• Disposal: Used or expired Ozempic pens should be disposed of properly. Do not throw them in the regular trash. Follow local guidelines or consult with your healthcare provider or pharmacist on how to safely dispose of the used pens. They may provide information on local medication disposal programs or recommend methods such as using sharps containers.

In case of emergency/overdose

• Contact emergency services: If you or someone else is experiencing severe symptoms or a medical emergency, call emergency services immediately.
• Inform healthcare professionals: Provide all necessary information about the medication, including the name (Ozempic), the dose taken, and the timing of the overdose.
• Poison Control Center: If available in your country, you can also contact the Poison Control Center helpline for guidance on how to manage the situation.

What other information should I know?

• Regular monitoring: Your healthcare provider may recommend regular monitoring of blood sugar levels, kidney function, and thyroid function while you are taking Ozempic. This helps ensure the medication is working effectively and to detect any potential adverse effects.
• Medication interactions: Inform your healthcare provider about all other medications, supplements, or herbal products you are taking, as they can potentially interact with Ozempic. This includes insulin or other medications that lower blood sugar levels.
• Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of Ozempic with your healthcare provider. The use of Ozempic during pregnancy and breastfeeding is generally not recommended.
• Follow-up appointments: Regular follow-up appointments with your healthcare provider are important to monitor your progress, discuss any concerns or side effects, and make any necessary adjustments to your treatment plan.

Always consult your healthcare provider or pharmacist for specific instructions, guidelines, and any additional information regarding the use, storage, disposal, and potential emergencies associated with Ozempic.