WARNING

Oxymorphone is a potent opioid medication used for the management of severe pain. While it can be effective in providing relief, there are certain risks associated with its use. Here are some of the potential risks of taking Oxymorphone:

• Addiction and dependence: Oxymorphone, like other opioids, has a high potential for addiction and dependence. Prolonged use or misuse of the drug can lead to physical and psychological dependence, requiring higher doses to achieve the same level of pain relief.
• Respiratory depression: One of the most serious risks of Oxymorphone is respiratory depression, where breathing becomes slow and shallow. This can be life-threatening, especially if the drug is taken in high doses or combined with other substances that depress the central nervous system, such as alcohol or sedatives.
• Overdose: Taking too much Oxymorphone can result in an overdose, which can be fatal. Symptoms of an overdose may include extreme drowsiness, confusion, slowed or stopped breathing, low blood pressure, and loss of consciousness. Prompt medical attention is essential in case of an overdose.
• Constipation: Opioids like Oxymorphone commonly cause constipation. This side effect can be managed with lifestyle changes, over-the-counter remedies, or prescription medications, but it may still persist and cause discomfort.
• CNS depression and drowsiness: Oxymorphone can cause central nervous system (CNS) depression, leading to drowsiness, sedation, and impaired cognitive and motor functions. Operating heavy machinery or driving a vehicle while under the influence of this medication can be dangerous.
• Withdrawal symptoms: When Oxymorphone use is stopped abruptly after prolonged use, withdrawal symptoms may occur. These can include anxiety, restlessness, muscle aches, insomnia, nausea, vomiting, and sweating. It is important to consult a healthcare professional for guidance on tapering off the medication if discontinuing its use.
• Drug interactions: Oxymorphone can interact with other medications, such as certain antidepressants, sedatives, antihistamines, and benzodiazepines, resulting in increased sedation, respiratory depression, and other adverse effects. It is crucial to inform your healthcare provider about all medications you are taking to avoid potential interactions.

It is important to note that the information provided here is a brief overview, and there may be additional risks and side effects associated with Oxymorphone. It is always recommended to consult with a healthcare professional who can assess your specific situation and provide personalized advice and guidance.

Why is this medication prescribed?

Oxymorphone is prescribed for the management of severe pain that requires around-the-clock treatment and cannot be effectively controlled with other pain medications. It belongs to the class of opioids, which are powerful analgesics (pain relievers).

Some common reasons why Oxymorphone may be prescribed include:

• Postoperative pain: Oxymorphone may be prescribed after surgical procedures to help manage acute pain during the recovery period.
• Chronic pain: It can be used to relieve chronic pain conditions such as cancer-related pain, severe back pain, neuropathic pain, or pain from other conditions that significantly impact a person’s quality of life.
• Palliative care: Oxymorphone may be prescribed for patients in palliative care, providing relief from severe pain in advanced stages of illness or at the end of life.
• Tolerance or inadequate response to other pain medications: In cases where other pain medications have become less effective or are not providing adequate relief, a healthcare professional may consider prescribing Oxymorphone as an alternative option.

How should this medicine be used?

Oxymorphone should be used exactly as prescribed by a healthcare professional. It is important to follow the instructions provided on the prescription label and consult with your doctor or pharmacist if you have any questions or concerns. Here are some general guidelines for the use of Oxymorphone:

• Dosage: Take Oxymorphone as directed by your healthcare provider. The dosage is typically individualized based on factors such as the severity of pain, previous opioid exposure, and your response to the medication. Do not exceed the prescribed dose or adjust the dosage without consulting your doctor.
• Administration: Oxymorphone is available in different forms, including immediate-release tablets, extended-release tablets, and extended-release capsules. Each formulation has different dosing instructions, so it is crucial to carefully read and follow the specific instructions provided by your healthcare provider.
• Timing: If you are taking immediate-release Oxymorphone tablets, they are usually taken every 4 to 6 hours as needed for pain relief. Extended-release formulations are designed to provide long-lasting pain control and are typically taken once or twice daily.
• Swallowing: Swallow the tablets or capsules whole with water. Do not crush, chew, dissolve, or break them unless instructed by your doctor, as it may lead to an increased risk of overdose or other adverse effects.
• Food: Oxymorphone can be taken with or without food, but it is generally recommended to take it consistently in the same manner for each dose.
• Avoid alcohol: It is important to avoid consuming alcohol while taking Oxymorphone, as it can increase the risk of side effects and may lead to dangerous respiratory depression or overdose.
• Regular monitoring: Your healthcare provider may need to monitor your response to the medication and adjust the dosage if necessary. Be sure to attend follow-up appointments and communicate any changes in your pain level or concerns about the medication.
• Discontinuation: If you and your doctor decide to stop using Oxymorphone, it is important to gradually reduce the dosage under medical supervision to minimize withdrawal symptoms.

Remember, this is a general overview of how Oxymorphone is typically used, and individual instructions may vary. Always consult with your healthcare provider for specific guidance based on your condition and medical history.

Other uses for this medicine

Oxymorphone is primarily prescribed for the management of severe pain. However, there are no other approved medical uses for Oxymorphone beyond pain relief. It is essential to use Oxymorphone only as directed by a healthcare professional and for its approved indications.

What special precautions should I follow?

When using Oxymorphone, there are several special precautions to keep in mind:

• Allergies: Inform your healthcare provider if you have any known allergies to Oxymorphone or other opioids. Additionally, disclose any history of allergic reactions to medications or other substances.
• Medical conditions: It is crucial to provide a comprehensive medical history to your doctor, especially if you have or have had conditions such as respiratory disorders, liver or kidney disease, head injury, brain tumors, seizures, mental health disorders, or a history of substance abuse.
• Pregnancy and breastfeeding: Inform your healthcare provider if you are pregnant or planning to become pregnant. Oxymorphone use during pregnancy can pose risks to the fetus, and the potential benefits and risks should be carefully evaluated. Oxymorphone may also pass into breast milk and can affect a nursing infant, so it is important to discuss the risks and benefits with your doctor if you are breastfeeding.
• Interactions with other medications: Oxymorphone can interact with other medications, including certain antidepressants, sedatives, antihistamines, benzodiazepines, and other opioids. These interactions can increase the risk of side effects, such as respiratory depression and sedation. Inform your healthcare provider about all the medications, supplements, and herbal products you are taking to ensure safe and effective use of Oxymorphone.
• Respiratory depression and sedation: Oxymorphone can cause respiratory depression, which can be life-threatening. It may also cause sedation and impair cognitive and motor functions. Avoid activities that require mental alertness, such as driving or operating machinery, until you know how Oxymorphone affects you.
• Misuse and addiction: Oxymorphone is a potent opioid with a high potential for misuse, abuse, and addiction. Follow your doctor’s instructions carefully, do not take more than the prescribed dose, and do not share the medication with others.
• Tolerance and dependence: Prolonged use of Oxymorphone can lead to tolerance, where higher doses are needed to achieve the same level of pain relief. It can also result in physical and psychological dependence. Do not abruptly stop taking Oxymorphone without consulting your doctor, as it may lead to withdrawal symptoms.

It is important to discuss any specific concerns or precautions related to Oxymorphone with your healthcare provider. They can provide personalized guidance based on your individual circumstances and help ensure the safe and effective use of the medication.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with Oxymorphone. However, it is generally recommended to take Oxymorphone consistently, either with or without food, for each dose. You can follow your normal dietary habits while taking this medication, unless otherwise advised by your healthcare provider.

What should I do if I forget a dose?

If you forget to take a dose of Oxymorphone, follow these general guidelines:

• Immediate-release Oxymorphone: If you are taking immediate-release tablets and miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
• Extended-release Oxymorphone: If you are taking extended-release formulations (tablets or capsules), it is important to follow your prescribed dosing schedule consistently. If you miss a dose, take it as soon as you remember, but only if there are at least 8-12 hours remaining before your next scheduled dose. If there is less time than that, skip the missed dose and continue with the next scheduled dose. Do not take two doses at the same time.

What side effects can this medication cause?

Oxymorphone is a potent opioid analgesic medication that is used to manage moderate to severe pain. Like other opioids, it can cause various side effects. Common side effects of oxymorphone can include:

• Nausea and vomiting: These are relatively common side effects and may be experienced especially during the initial stages of treatment. Taking the medication with food may help reduce these symptoms.
• Constipation: Opioids are known to cause constipation by slowing down the movement of the digestive tract. Increasing fluid intake, dietary fiber, and physical activity can help alleviate this side effect. Laxatives may also be prescribed if necessary.
• Drowsiness and dizziness: Oxymorphone can cause sedation and impair cognitive function. It is important to avoid activities that require alertness, such as driving or operating machinery, until you know how the medication affects you.
• Respiratory depression: High doses of oxymorphone can depress the respiratory system, leading to slowed breathing or even respiratory arrest. This is more likely to occur in individuals who are already at risk, such as those with respiratory conditions or the elderly.
• Itching and skin rash: Some people may experience itching or develop a skin rash while taking oxymorphone. If this occurs, it is important to inform your healthcare provider.
• Sweating: Increased sweating can be a side effect of oxymorphone. This can be bothersome for some individuals but is generally not a cause for concern.
• Urinary retention: Opioids can affect the bladder and cause difficulty in urination or urinary retention. If you experience any changes in urination patterns or discomfort, it is important to notify your doctor.
• Hypotension: Oxymorphone can cause low blood pressure in some individuals. This can lead to dizziness or lightheadedness when standing up from a seated or lying position.
• Hormonal effects: Prolonged use of opioids like oxymorphone can affect hormone levels, particularly testosterone and cortisol. This can lead to symptoms such as decreased libido, fatigue, and mood changes.

It is essential to remember that these are not the only possible side effects of oxymorphone, and individual experiences may vary. It’s crucial to follow your healthcare provider’s instructions and report any unexpected or concerning side effects promptly.

What should I know about storage and disposal of this medication?

Storage:

• Store Oxymorphone at room temperature, away from moisture and heat.
• Keep the medication out of reach of children and pets, as it can be harmful if accidentally ingested.
• Store Oxymorphone in its original container with the label intact to ensure proper identification.

Disposal:

• Properly dispose of unused or expired Oxymorphone to prevent accidental ingestion or misuse.
• Follow any specific disposal instructions provided by your healthcare provider or local guidelines.
• Do not flush Oxymorphone down the toilet or drain unless specifically instructed to do so.

In case of emergency/overdose

• Call emergency services: If you or someone else is experiencing a medical emergency or suspected overdose, call emergency services immediately (e.g., 911 in the United States) for immediate assistance.
• Follow medical advice: Follow any specific instructions given by emergency medical personnel or poison control center operators.

What other information should I know?

• Regular monitoring: Your healthcare provider may periodically monitor your response to Oxymorphone and adjust your dosage as needed. Attend follow-up appointments and communicate any changes in your pain levels or concerns about the medication.
• Avoid alcohol and certain medications: Avoid consuming alcohol while taking Oxymorphone, as it can increase the risk of side effects and may lead to dangerous respiratory depression or overdose. Inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential drug interactions.
• Tolerance and dependence: Prolonged use of Oxymorphone can lead to tolerance, where higher doses are needed to achieve the same level of pain relief. It can also result in physical and psychological dependence. Do not abruptly stop taking Oxymorphone without consulting your doctor, as it may lead to withdrawal symptoms.
• Follow prescribing instructions: Take Oxymorphone exactly as prescribed by your healthcare provider. Do not exceed the prescribed dose or adjust the dosage without consulting your doctor.
• Keep healthcare providers informed: Inform all healthcare professionals involved in your care about your Oxymorphone use, including dentists, surgeons, and emergency medical personnel. This ensures they have a complete understanding of your medication regimen and can make informed decisions about your treatment.

It is important to note that this information provides a general overview. Always consult with your healthcare provider or pharmacist for specific instructions, guidelines, and advice regarding the storage, disposal, and emergency situations related to Oxymorphone.