Why is this medication prescribed?

When the disease has advanced after receiving treatment with at least one additional hormone therapy, adults with certain forms of hormone receptor-positive breast cancer (breast cancer that depends on hormones like estrogen to thrive) are prescribed elacestrant. Elacestrant belongs to the group of drugs known as estrogen receptor antagonists. By preventing estrogen from binding, it inhibits the proliferation of cancer cells that are dependent on estrogen.

How should this medicine be used?

The oral tablet form of elacestrant is available. It is typically taken once daily with food. At roughly the same time each day, take elacestrant. Ask your doctor or pharmacist to explain any instructions on your prescription label that you do not understand, and carefully follow their instructions. Administer elacestrant precisely as prescribed. Never take it in quantities or frequencies other than those recommended by your doctor.

Do not split, chew, or crush the tablets; rather, swallow them whole.

Based on any side effects you could have, your doctor can decide to adjust your dose or instruct you to discontinue taking elacestrant. If you experience any side effects while taking the medication, be sure to let your doctor know. If your doctor has not instructed you to stop taking the medication, do not.

The manufacturer’s information for the patient can be obtained by asking your pharmacist or doctor.

Other uses for this medicine

Elacestrant was on its potential use in hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer. However, it’s worth noting that ongoing research and clinical trials may explore its efficacy in other settings or conditions.

What special precautions should I follow?

However, general precautions associated with similar medications in the same class (selective estrogen receptor degraders) may apply. These precautions may include:

• Pregnancy and breastfeeding: Elacestrant may have harmful effects on a developing fetus, so it is important to inform your healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding.
• Liver function: Some medications in this class may affect liver function, so regular monitoring of liver enzymes may be necessary during treatment. Inform your healthcare professional about any pre-existing liver conditions.
• Drug interactions: Elacestrant may interact with other medications, including over-the-counter drugs and herbal supplements. It is important to inform your healthcare professional about all medications you are taking to avoid potential interactions.
• Side effects: Like any medication, Elacestrant may have side effects. Common side effects observed in clinical trials included fatigue, nausea, diarrhea, decreased appetite, and hot flashes. However, specific side effect profiles may vary, and it is essential to discuss potential side effects with your healthcare professional.

It is important to remember that these precautions are general in nature and may not be specific to Elacestrant. Always consult the prescribing information or your healthcare professional for the most accurate and up-to-date information on precautions associated with a particular medication.

What special dietary instructions should I follow?

However, in general, it is advisable to follow a balanced and healthy diet while taking any medication. A well-rounded diet that includes a variety of fruits, vegetables, whole grains, lean proteins, and adequate hydration is generally recommended for overall health and well-being.

What should I do if I forget a dose?

Regarding a missed dose, it’s important to consult the prescribing information or your healthcare professional for specific instructions, as they may vary depending on the medication and dosage schedule. However, as a general guideline:

• If you forget to take a dose of Elacestrant, take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule.
• Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

However, based on the available information from clinical studies, the following side effects were commonly observed:

• Fatigue
• Nausea
• Diarrhea
• Decreased appetite
• Hot flashes

It’s important to note that this is not an exhaustive list, and other side effects may occur. Furthermore, the frequency and severity of side effects can vary from person to person.

If you are prescribed Elacestrant or any other medication, it’s crucial to discuss potential side effects with your healthcare professional. They can provide you with detailed information about the specific side effect profile associated with the medication, as well as guidance on managing or mitigating any side effects that may occur.

If you experience any unexpected or severe side effects while taking Elacestrant, it is important to promptly contact your healthcare professional for further evaluation and guidance. They can assess your situation and provide appropriate medical advice.

What should I know about storage and disposal of this medication?

Storage instructions for medications typically include:

• Store Elacestrant at room temperature unless otherwise specified.
• Keep it in its original container, away from moisture and direct sunlight.
• Store it out of reach of children and pets.

Disposal instructions for medications typically include:

• Follow any specific disposal instructions provided with the medication, such as returning unused medications to a designated take-back program or pharmacy.
• If no specific instructions are available, consult your healthcare professional or pharmacist for guidance on how to properly dispose of the medication.

In case of emergency/overdose

In case of an emergency or overdose, it is important to seek immediate medical attention or contact your local poison control center. Be prepared to provide them with information such as the name of the medication (Elacestrant), the dosage strength, and the amount ingested (if known). If possible, have the medication container or packaging available for reference.

What other information should I know?

It’s also important to inform your healthcare professional about any other medications, supplements, or medical conditions you have, as they can provide you with comprehensive guidance on the use, storage, and disposal of Elacestrant based on your individual circumstances.

It is recommended to consult the prescribing information or reach out to a healthcare professional or pharmacist for the most accurate and up-to-date information on storage, disposal, and emergency procedures related to Elacestrant or any other medication.