WARNING

Taking Opana (oxymorphone) carries several risks, which is why it is important to use this medication under the close supervision of a healthcare professional. Here are some of the risks associated with Opana:

• Addiction and Dependency: Opana belongs to the opioid class of drugs, which have a high potential for addiction and dependence. Prolonged use or misuse of Opana can lead to physical and psychological dependence, making it challenging to stop using the medication without experiencing withdrawal symptoms.
• Respiratory Depression: Opana, like other opioids, can cause respiratory depression, which is a potentially life-threatening condition. It slows down breathing, and in high doses or when combined with other depressant substances (such as alcohol), it can lead to shallow or stopped breathing.
• Sedation and Impaired Judgement: Opana can cause drowsiness, sedation, and impaired cognitive function. These effects can impair judgment, coordination, and reaction times, increasing the risk of accidents, falls, or other injuries.
• Gastrointestinal Effects: Opana can cause constipation, nausea, vomiting, and other gastrointestinal issues. These side effects can be bothersome and may require additional medications to manage.
• Drug Interactions: Opana can interact with other medications, particularly other central nervous system depressants such as benzodiazepines or alcohol, leading to increased sedation, respiratory depression, and the risk of overdose.
• Overdose: Taking high doses of Opana or combining it with other substances can lead to an overdose, which can be life-threatening. Overdose symptoms include extreme drowsiness, slowed or stopped breathing, loss of consciousness, and can potentially result in death.

It’s crucial to follow your healthcare professional’s instructions carefully, use the lowest effective dose for the shortest duration, and report any concerning symptoms or side effects while taking Opana. Regular communication with your doctor is essential to monitor the medication’s effectiveness, adjust the dosage if needed, and ensure your safety and well-being.

Why is this medication prescribed?

Opana (oxymorphone) is a potent opioid analgesic medication that is prescribed for the management of moderate to severe pain. It is typically used when other pain medications, such as non-opioid analgesics or weaker opioids, have not provided sufficient pain relief or are not tolerated by the patient.

Opana belongs to a class of drugs called opioid agonists, which work by binding to specific receptors in the brain and spinal cord to reduce the perception of pain. It is often used for the treatment of acute pain following surgery or injury, as well as chronic pain conditions such as cancer pain or severe musculoskeletal pain.

It’s important to note that Opana is a controlled substance due to its high potential for abuse and addiction. It should only be used under the strict supervision of a healthcare professional and for the specific pain condition it is prescribed for. Misuse or prolonged use of Opana can lead to serious side effects and dependency.

How should this medicine be used?

Opana (oxymorphone) should be used exactly as prescribed by your healthcare professional. It is important to follow the prescribed dosage, frequency, and duration of use. Here are some general guidelines for using Opana:

• Prescription Guidelines: Take Opana exactly as prescribed by your doctor. Do not take more or less than the prescribed dose, and do not take it more frequently or for a longer duration than recommended.
• Oral Administration: Opana is typically taken orally as a tablet. Swallow the tablet whole with water. Do not crush, chew, break, or dissolve the tablet unless specifically instructed by your doctor.
• Dosage Adjustment: Your doctor will determine the appropriate starting dose based on your pain level and individual factors. The dosage may be adjusted gradually to achieve adequate pain relief with the fewest possible side effects.
• Individualized Treatment: Opana dosages are tailored to the individual, taking into account factors such as age, weight, overall health, and response to the medication. Do not share your medication with others, as it may not be safe or suitable for them.
• Follow-up Appointments: Regularly communicate with your doctor while taking Opana. Attend follow-up appointments to assess the effectiveness of the medication, discuss any side effects or concerns, and make any necessary adjustments to your treatment plan.
• Avoid Alcohol and Other Depressants: It is crucial to avoid consuming alcohol or taking other central nervous system depressant medications while using Opana. Combining these substances can increase the risk of sedation, respiratory depression, and other serious side effects.
• Tapering Off: If your doctor decides to discontinue Opana, they will provide specific instructions on how to gradually reduce the dosage to minimize withdrawal symptoms. Do not abruptly stop taking Opana without medical guidance.

Remember, Opana is a potent opioid medication with a high potential for abuse and addiction. Use it only as prescribed, and never share it with others. If you have any questions or concerns about how to use Opana, consult your healthcare professional for guidance.

Other uses for this medicine

Opana (oxymorphone) is primarily prescribed for the management of moderate to severe pain. However, it is important to note that the use of Opana for any other purposes or conditions should only be determined by a healthcare professional. Off-label use of medications can carry additional risks and may not be safe or effective.

What special precautions should I follow?

Regarding special precautions for Opana, here are some important considerations:

• Allergies: Inform your doctor if you have any known allergies to Opana or any other opioids. This medication may contain inactive ingredients that can cause allergic reactions or other problems.
• Medical Conditions: Discuss your complete medical history with your healthcare provider before starting Opana. Inform them if you have any history of respiratory disorders, liver or kidney disease, a history of substance abuse, mental health conditions, or any other significant health issues.
• Pregnancy and Breastfeeding: Opana is not recommended for use during pregnancy as it may harm the unborn baby. It can also pass into breast milk and harm a nursing infant. Consult with your healthcare provider regarding the potential risks and benefits if you are pregnant, planning to become pregnant, or breastfeeding.
• Drug Interactions: Inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Opana can interact with certain medications, such as sedatives, tranquilizers, antidepressants, and monoamine oxidase inhibitors (MAOIs). These interactions can lead to increased sedation, respiratory depression, and other adverse effects.
• Respiratory Depression: Opana can cause respiratory depression, which can be life-threatening. This risk is higher in individuals with respiratory conditions, elderly patients, and those taking high doses of the medication. Monitor your breathing and seek immediate medical attention if you experience difficulty breathing or slow/shallow breathing.
• Dependence and Withdrawal: Opana can lead to physical and psychological dependence with prolonged use. Abruptly stopping the medication or reducing the dosage without medical guidance can result in withdrawal symptoms. Your doctor will provide instructions on how to taper off the medication gradually if necessary.

It is crucial to follow your healthcare professional’s advice, including dosage instructions, precautions, and any additional recommendations specific to your situation. If you have any concerns or questions about using Opana, consult your healthcare provider for personalized guidance.

What special dietary instructions should I follow?

If you have been prescribed Opana, it is crucial to follow the specific instructions provided by your healthcare provider or pharmacist. They will give you detailed information on how to take the medication, including any dietary instructions or restrictions that may apply.

What should I do if I forget a dose?

Regarding a missed dose, it is important to take Opana as prescribed. If you forget to take a dose, it is generally recommended to take it as soon as you remember. However, if it is close to the time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. It’s important not to take a double dose to make up for a missed one, as this can increase the risk of side effects and overdose.

What side effects can this medication cause?

Opana (oxymorphone) is a potent opioid pain medication. Like other opioids, Opana can cause several side effects, including:

1. Common side effects:
   • Constipation: Opana can slow down bowel movements, leading to constipation.
   • Nausea and vomiting: These gastrointestinal symptoms are common with opioid use.
   • Drowsiness: Opana can cause drowsiness, sedation, or fatigue.
   • Dizziness: Some individuals may experience dizziness or lightheadedness.
   • Headache: Headaches can occur as a side effect of Opana.
2. Respiratory effects:
   • Respiratory depression: Opana, like other opioids, can suppress breathing, particularly in high doses or when combined with other respiratory depressants (e.g., alcohol, sedatives).
   • Slowed breathing: Opana can cause breathing to become slower and shallower.
3. Cardiovascular effects:
   • Low blood pressure: Opana can cause a decrease in blood pressure, leading to lightheadedness or fainting.
   • Slow heart rate: Opana may lower heart rate, resulting in bradycardia.
4. Central nervous system effects:
   • Confusion: Opana can cause mental confusion or disorientation, especially in higher doses.
   • Sedation: Opana has sedating properties and can induce drowsiness or sleepiness.
   • Mood changes: Some individuals may experience changes in mood, such as euphoria, anxiety, or depression.
   • Impaired coordination: Opana can affect motor skills, coordination, and reaction times.
5. Other side effects:
   • Itching or rash: Opana may cause itching or skin rashes in some individuals.
   • Sweating: Excessive sweating or diaphoresis can occur with Opana use.
   • Urinary retention: Opana can make it difficult to empty the bladder completely.
   • Hormonal effects: Prolonged use of opioids like Opana may disrupt hormone levels, leading to issues like low testosterone or menstrual irregularities.

It’s important to note that this list is not exhaustive, and individual responses to Opana can vary. Some side effects can be severe and require immediate medical attention. Always consult your healthcare provider for complete information on the potential side effects of any medication and seek medical help if you experience any concerning symptoms.

What should I know about storage and disposal of this medication?

Storage:

• Keep Opana in a safe and secure place, away from children, pets, and individuals who might misuse or abuse it.
• Store Opana at room temperature, away from excessive heat or moisture.
• Keep Opana in its original container, with the lid tightly closed.

Disposal:

• Dispose of unused or expired Opana properly according to local guidelines and regulations. Contact your local pharmacy, healthcare provider, or waste management authority to learn about the safe disposal methods available in your area.
• Do not dispose of Opana by flushing it down the toilet or pouring it down the drain unless specifically instructed to do so.

In case of emergency/overdose

• Call emergency services: If you suspect an overdose or encounter a medical emergency, call your local emergency number (e.g., 911 in the United States) right away.
• Stay with the person: If someone has overdosed on Opana, stay with them and monitor their condition until emergency medical personnel arrive.
• Provide information: When contacting emergency services, provide them with all relevant information, including the person’s symptoms, the quantity of Opana ingested (if known), and any other substances that may have been taken concurrently.

What other information should I know?

• Opana addiction and dependence: Opana is a potent opioid medication with a high potential for addiction and dependence. Prolonged use can lead to physical and psychological dependence. Abruptly stopping Opana or reducing the dose without medical guidance can result in withdrawal symptoms.
• Avoid alcohol and other substances: Combining Opana with alcohol, sedatives, or other central nervous system depressants can increase the risk of serious side effects, including respiratory depression and overdose.
• Driving and operating machinery: Opana can impair cognitive and motor functions. Avoid driving or operating machinery until you know how Opana affects you.
• Pregnancy and breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Opana can have adverse effects on the fetus and may pass into breast milk.
• Interactions with other medications: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as Opana may interact with certain substances, including other opioids, benzodiazepines, and certain antidepressants.

Always consult your healthcare provider or pharmacist for complete and up-to-date information specific to your situation regarding the storage, disposal, and emergency management of Opana.