Why is this medication prescribed?

Onzetra Xsail Nasal Powder is a medication that was acute treatment of migraine headaches with or without aura in adults. It contains the active ingredient sumatriptan, which belongs to a class of drugs known as triptans.

Migraine headaches are a type of headache characterized by severe throbbing pain, usually on one side of the head, along with other symptoms such as nausea, vomiting, and sensitivity to light and sound. Onzetra Xsail Nasal Powder is specifically designed to deliver sumatriptan as a nasal powder, providing a non-oral route of administration for faster and more effective relief of migraine symptoms.

The powder is self-administered by the patient using the Xsail delivery device. When inhaled through the nose, the sumatriptan in Onzetra Xsail Nasal Powder acts by constricting blood vessels in the brain and reducing inflammation, thereby alleviating the pain and other symptoms associated with migraines.

How should this medicine be used?

Onzetra Xsail Nasal Powder should be used as directed by a healthcare professional. It is important to carefully follow the instructions provided with the medication. Here is a general guide on how to use Onzetra Xsail Nasal Powder:

• Prepare the Xsail delivery device: Before using Onzetra Xsail, you need to assemble the Xsail delivery device. Follow the instructions provided to ensure proper assembly.
• Prime the device: Hold the device upright and pull the grey lever away from the device until it clicks. Repeat this step four more times to make sure the device is primed before the first use or if it has not been used for more than 2 weeks.
• Administer the medication: Once the device is primed, place the device’s nosepiece just inside one nostril, making sure to close the other nostril with your finger. Breathe in gently through the nose while simultaneously pressing the plunger firmly to release the medication. Inhale steadily and remove the device from the nostril.
• Repeat for the other nostril: If a second dose is prescribed, repeat the same process for the other nostril.
• Cleaning the device: After use, wipe the device’s exterior with a clean, dry tissue or cloth. Do not rinse or wash the device.

It is important to note that the dosage and frequency of Onzetra Xsail Nasal Powder will be determined by a healthcare professional based on your specific condition. Do not exceed the prescribed dose, and always follow the instructions provided by your healthcare provider.

If you have any doubts or questions about how to use Onzetra Xsail Nasal Powder, it is recommended to consult your healthcare professional or pharmacist for clarification and guidance.

Other uses for this medicine

Onzetra Xsail Nasal Powder is specifically approved for the acute treatment of migraine headaches in adults and is not typically used for other purposes. The medication contains sumatriptan, a drug that specifically targets migraines.

What special precautions should I follow?

As for special precautions, it’s important to consider the following:

• Allergies: Inform your healthcare professional if you have any known allergies to sumatriptan or any other components of Onzetra Xsail Nasal Powder. This medication should not be used if you are allergic to sumatriptan.
• Cardiovascular conditions: Onzetra Xsail Nasal Powder should be used with caution if you have a history of cardiovascular conditions such as heart disease, high blood pressure, or a history of heart attacks. It may cause constriction of blood vessels, which could exacerbate these conditions.
• Stroke or transient ischemic attack (TIA): Use of Onzetra Xsail Nasal Powder is generally contraindicated in individuals with a history of stroke or TIA due to the potential risk of worsening these conditions.
• Other medical conditions: Inform your healthcare provider about any other medical conditions you have, including liver or kidney problems. Special caution may be needed in these cases.
• Medication interactions: Certain medications, including other migraine medications, antidepressants, and certain antibiotics, may interact with Onzetra Xsail Nasal Powder. It’s important to provide a complete list of all medications you are taking to your healthcare professional to avoid potential interactions.
• Pregnancy and breastfeeding: The use of Onzetra Xsail Nasal Powder during pregnancy or breastfeeding is generally not recommended. Consult with your healthcare provider for specific guidance if you are pregnant, planning to become pregnant, or breastfeeding.
• Side effects: Onzetra Xsail Nasal Powder may cause side effects, including but not limited to, nasal discomfort, altered sense of taste, nasal congestion, and throat irritation. If you experience any unexpected or severe side effects, contact your healthcare professional.

Remember, it is crucial to consult with a healthcare professional or pharmacist to discuss your specific medical history, medications, and any potential precautions or contraindications associated with the use of Onzetra Xsail Nasal Powder. They will provide you with personalized advice and guidance based on your individual circumstances.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with the use of Onzetra Xsail Nasal Powder. However, it’s generally recommended to follow a healthy and balanced diet while taking any medication.

What should I do if I forget a dose?

If you happen to miss a dose of Onzetra Xsail Nasal Powder, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

What side effects can this medication cause?

Onzetra Xsail Nasal Powder, containing sumatriptan, may cause side effects. Not all individuals who use the medication will experience side effects, and their severity can vary.

Common side effects of Onzetra Xsail Nasal Powder may include:

• Unpleasant taste or changes in taste perception
• Nasal discomfort, such as irritation, burning sensation, or itching
• Nasal congestion or stuffiness
• Discomfort or pain in the throat
• Nausea or vomiting
• Dizziness or lightheadedness

These side effects are usually temporary and may subside on their own. However, if they persist or become bothersome, it is recommended to consult your healthcare professional for further evaluation.

In rare cases, more serious side effects may occur. Seek immediate medical attention if you experience any of the following:

• Chest pain or tightness
• Rapid or irregular heartbeat
• Severe or persistent headache
• Severe dizziness or fainting
• Numbness or weakness, especially on one side of the body
• Severe stomach pain or bloody diarrhea
• Allergic reactions, such as rash, itching, swelling, or difficulty breathing

It’s important to note that this is not an exhaustive list of possible side effects. Other side effects may occur. If you notice any unusual symptoms or have concerns about side effects while using Onzetra Xsail Nasal Powder, contact your healthcare professional for advice.

As always, it’s recommended to consult your healthcare professional or pharmacist for a complete list of potential side effects associated with Onzetra Xsail Nasal Powder, as well as any specific instructions or precautions relevant to your individual medical condition.

What should I know about storage and disposal of this medication?

Storage and disposal:

• Store Onzetra Xsail Nasal Powder at room temperature, away from excessive heat and moisture.
• Keep the medication out of the reach of children and pets.
• Do not transfer the powder from the original packaging into another container.
• Safely discard any unused or expired medication as instructed by your healthcare professional or pharmacist. Do not dispose of it in household trash or flush it down the toilet unless specifically instructed to do so.

In case of emergency/overdose

• In case of an emergency or suspected overdose, immediately contact your local emergency services or go to the nearest emergency room.
• Overdose symptoms may include severe chest pain, shortness of breath, irregular heartbeats, or seizures. It’s important to seek immediate medical attention if you suspect an overdose.

What other information should I know?

• Onzetra Xsail Nasal Powder is prescribed for your specific condition. Do not share the medication with others, even if they have similar symptoms.
• Keep a record of your medication usage and note any changes or patterns in your migraine attacks. This information can be valuable for your healthcare professional to assess the effectiveness of the treatment.
• Attend regular follow-up appointments with your healthcare professional to monitor your progress and discuss any concerns or changes in your condition.
• Inform all healthcare providers involved in your care about your use of Onzetra Xsail Nasal Powder, including dentists and specialists, to ensure they have a complete understanding of your medications.

Remember, this information is not exhaustive, and it’s essential to consult your healthcare professional or pharmacist for comprehensive guidance on storage, disposal, and emergency situations related to Onzetra Xsail Nasal Powder. They can provide specific instructions based on your individual needs and circumstances.