WARNING

Noctiva Nasal (desmopressin acetate) is a medication used to treat nocturia, a condition characterized by excessive urination at night. While Noctiva Nasal can be effective in managing nocturia symptoms, it is important to be aware of the potential risks associated with its use. Here are some of the key risks:

• Hyponatremia: Noctiva Nasal can cause a decrease in sodium levels in the blood, leading to a condition called hyponatremia. This can result in symptoms such as headache, nausea, vomiting, confusion, seizures, and, in severe cases, even coma or death. It is crucial to follow the prescribed dosage and monitoring guidelines to minimize the risk of hyponatremia.
• Fluid retention: Noctiva Nasal can cause fluid retention, leading to swelling in the hands, ankles, or feet. If you notice any unusual or significant swelling, it is important to notify your healthcare provider.
• Increased blood pressure: Noctiva Nasal may cause an increase in blood pressure, especially in individuals with a history of hypertension or cardiovascular disease. Regular monitoring of blood pressure is necessary during treatment.
• Nasal discomfort: Noctiva Nasal is administered through the nose and may cause nasal discomfort, such as nasal irritation, congestion, or a runny nose. These side effects are usually mild and temporary.
• Allergic reactions: Although rare, some individuals may experience an allergic reaction to Noctiva Nasal. Signs of an allergic reaction include rash, itching, swelling, severe dizziness, or difficulty breathing. If any of these symptoms occur, seek immediate medical attention.

It is essential to consult with your healthcare provider before starting Noctiva Nasal to discuss the potential risks and benefits specific to your situation. They can provide personalized guidance and monitor your response to the medication to ensure your safety.

Why is this medication prescribed?

Noctiva Nasal (desmopressin acetate) is a prescription medication that is used to treat nocturia in adults. Nocturia is a condition characterized by excessive urination at night, which can disrupt sleep and negatively impact quality of life. It is a common symptom in conditions such as overactive bladder, benign prostatic hyperplasia (enlarged prostate), and diabetes insipidus.

Desmopressin acetate, the active ingredient in Noctiva Nasal, is a synthetic version of a hormone called vasopressin or antidiuretic hormone (ADH). It works by reducing the amount of urine produced by the kidneys and increasing water reabsorption, thus decreasing the frequency of nighttime urination.

Noctiva Nasal is typically prescribed when other lifestyle changes and treatments have been ineffective in managing nocturia. It is important to note that the use of Noctiva Nasal should be carefully considered and prescribed by a healthcare professional, as it may not be suitable for everyone. It is essential to follow the prescribed dosage and guidelines provided by your healthcare provider when using Noctiva Nasal or any other medication.

How should this medicine be used?

As with any medication, it is crucial to follow the instructions provided by your healthcare provider and the specific guidelines provided on the packaging of Noctiva Nasal. Here are some general instructions for using Noctiva Nasal, but please note that these may not be specific to the particular formulation or dosage prescribed to you:

• Administer the medication in the nose: Noctiva Nasal is designed to be used intranasally (in the nose). It is available as a nasal spray.
• Proper preparation: Before using the nasal spray, make sure to remove the protective cap and prime the pump. Priming helps ensure the correct dosage and proper spray function. Follow the specific priming instructions provided with your medication.
• Nasal administration: Tilt your head slightly forward and insert the nozzle of the spray into one nostril. Close the other nostril by gently pressing your finger against it. Breathe gently through your mouth while administering the spray as directed by your healthcare provider. Avoid tilting your head back or sniffing forcefully during the administration.
• Repeat for the other nostril: If instructed, repeat the same steps for the other nostril.
• Follow dosage instructions: The dosage and frequency of Noctiva Nasal will be determined by your healthcare provider based on your individual needs. It is important to adhere to the prescribed dosage and not exceed the recommended amount.
• Timing of administration: Noctiva Nasal is usually administered approximately 30 minutes before bedtime to maximize its effectiveness in reducing nighttime urination. Follow the timing instructions provided by your healthcare provider.
• Regular monitoring: Your healthcare provider may periodically evaluate the effectiveness of Noctiva Nasal and make any necessary adjustments to the dosage or treatment plan.

Remember to consult your healthcare provider or pharmacist for specific instructions on how to use Noctiva Nasal as they will be able to provide the most accurate and up-to-date information based on your individual circumstances and the specific formulation of the medication you have been prescribed.

Other uses for this medicine

Noctiva Nasal (desmopressin acetate) is primarily prescribed for the treatment of nocturia in adults, as mentioned earlier. Nocturia is excessive urination at night, which can disrupt sleep. However, it’s important to note that the use of Noctiva Nasal for other conditions or off-label purposes should only be done under the guidance and prescription of a healthcare professional.

What special precautions should I follow?

Regarding special precautions, it is crucial to discuss your medical history and current medications with your healthcare provider before using Noctiva Nasal. Here are some general precautions to consider:

• Hyponatremia: Noctiva Nasal affects the balance of water and electrolytes in the body. People with a history of low blood sodium levels (hyponatremia) or conditions that may increase the risk of hyponatremia should use Noctiva Nasal with caution. Your healthcare provider will monitor your electrolyte levels during treatment.
• Fluid intake restriction: Your healthcare provider may advise you to restrict fluid intake while using Noctiva Nasal to avoid water overload and hyponatremia. Follow the fluid intake guidelines provided by your healthcare provider.
• Concomitant medications: Inform your healthcare provider about all medications, including prescription drugs, over-the-counter medications, and supplements, that you are taking. Certain medications may interact with Noctiva Nasal, potentially affecting its effectiveness or increasing the risk of adverse effects.
• Medical conditions: Noctiva Nasal may not be suitable for individuals with certain medical conditions such as kidney problems, heart disease, high blood pressure, fluid retention, or a history of nasal or sinus surgery. Discuss your medical history thoroughly with your healthcare provider.
• Pregnancy and breastfeeding: Noctiva Nasal may not be recommended during pregnancy or breastfeeding. It is important to inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
• Children and adolescents: The safety and effectiveness of Noctiva Nasal in individuals under 18 years of age have not been established. Its use in this population is generally not recommended.

These precautions are not exhaustive, and there may be other specific considerations based on your individual health status and medical history. Always consult your healthcare provider for personalized advice and guidance before using Noctiva Nasal or any other medication.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with the use of Noctiva Nasal (desmopressin acetate). However, it is generally recommended to follow a balanced and healthy diet as advised by your healthcare provider.

What should I do if I forget a dose?

If you forget to take a dose of Noctiva Nasal, it is recommended to take the missed dose as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, it is better to skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed dose.

What side effects can this medication cause?

Noctiva Nasal (desmopressin acetate) may cause side effects in some individuals. It’s important to note that not all people using the medication will experience side effects, and the severity and frequency of side effects can vary. It is essential to discuss potential side effects with your healthcare provider before starting Noctiva Nasal. Here are some commonly reported side effects associated with Noctiva Nasal:

• Nasal discomfort: This can include symptoms such as nasal congestion, irritation, dryness, itching, or a burning sensation.
• Nasal bleeding: Some individuals may experience nosebleeds or blood-tinged nasal discharge. If bleeding is severe or persistent, seek medical attention.
• Headache: Headaches are a commonly reported side effect of Noctiva Nasal.
• Nasal congestion: Noctiva Nasal may cause temporary nasal congestion or stuffiness.
• Dizziness: Some people may experience dizziness or lightheadedness while using Noctiva Nasal.
• Nausea: Nausea or an upset stomach can occur as a side effect of the medication.
• Vomiting: In some cases, Noctiva Nasal may cause vomiting.
• Fatigue: Some individuals may experience increased tiredness or fatigue.
• Water retention or swelling: Noctiva Nasal can cause fluid retention, leading to swelling in the hands, feet, ankles, or other parts of the body.
• Hyponatremia: Noctiva Nasal affects the water and electrolyte balance in the body and may cause low blood sodium levels (hyponatremia). Signs of hyponatremia may include confusion, headache, nausea, seizures, or in severe cases, coma. Contact your healthcare provider if you experience any of these symptoms.

It’s important to promptly report any side effects you experience to your healthcare provider. They can evaluate the symptoms and determine the appropriate course of action, which may include adjusting the dosage or discontinuing the medication if necessary.

This list of side effects is not exhaustive, and other potential side effects may occur. It is always recommended to consult with your healthcare provider or refer to the product’s packaging for comprehensive information on potential side effects associated with Noctiva Nasal.

What should I know about storage and disposal of this medication?

• Storage: Noctiva Nasal should be stored at room temperature, away from direct sunlight, heat, and moisture. It is important to follow the storage recommendations provided with your specific formulation of Noctiva Nasal.
• Disposal: Dispose of Noctiva Nasal properly as per local regulations and guidelines. Do not dispose of it in household trash or flush it down the toilet unless specifically instructed to do so. Consult your pharmacist or healthcare provider for proper disposal methods.

In case of emergency/overdose

In case of emergency or overdose, contact your local emergency services or go to the nearest emergency room immediately. Symptoms of an overdose may include severe headache, nausea, vomiting, confusion, drowsiness, seizures, and in severe cases, potentially life-threatening complications. It is important to seek immediate medical attention if you suspect an overdose or experience any severe symptoms.

What other information should I know?

• Regular follow-up: Your healthcare provider may schedule regular follow-up appointments to monitor your response to Noctiva Nasal and adjust the treatment plan if needed. Attend these appointments as scheduled and communicate any concerns or changes in your condition to your healthcare provider.
• Medication interactions: Inform your healthcare provider about all medications, including prescription drugs, over-the-counter medications, and supplements, that you are taking. Some medications may interact with Noctiva Nasal and affect its effectiveness or increase the risk of side effects.
• Allergies: If you have a known allergy to desmopressin acetate or any other ingredients in Noctiva Nasal, inform your healthcare provider before using the medication.
• Avoid alcohol consumption: Drinking alcohol while using Noctiva Nasal may increase the risk of side effects such as dizziness or drowsiness. It is advisable to avoid or limit alcohol consumption during treatment.
• Driving and operating machinery: Noctiva Nasal may cause dizziness or drowsiness. If you experience these side effects, avoid driving or operating machinery until you know how the medication affects you.

It is essential to follow the specific instructions provided by your healthcare provider and carefully read the information provided with Noctiva Nasal for comprehensive and accurate guidance on its use, storage, disposal, and any additional precautions or considerations.