Why is this medication prescribed?

Nitro-Dur Patch is a prescription medication that contains nitroglycerin, a type of medication called a nitrate. It is primarily prescribed for the treatment and prevention of angina pectoris, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart.

Nitroglycerin works by dilating (widening) the blood vessels, including the coronary arteries that supply the heart muscle with oxygen and nutrients. This dilation helps to increase blood flow to the heart, relieving the chest pain associated with angina. By improving blood supply, Nitro-Dur Patch can also help prevent angina attacks.

The patch form of nitroglycerin allows for a slow and continuous release of the medication through the skin. It is usually applied to a clean, dry area of the skin on the chest, upper arm, or back and provides a steady level of nitroglycerin in the bloodstream over a period of 24 hours. This sustained release helps maintain a stable blood concentration of the medication, providing ongoing relief from angina symptoms.

How should this medicine be used?

Nitro-Dur Patch should be used exactly as prescribed by your healthcare provider. It is important to carefully follow the instructions provided with the medication. Here are general guidelines for using Nitro-Dur Patch:

• Skin Preparation: Choose a clean, dry area of skin on your chest, upper arm, or back to apply the patch. Avoid areas with cuts, irritation, or excessive hair. Clean the selected area with mild soap and water, and dry it thoroughly before applying the patch.
• Application: Remove the patch from its protective pouch and peel off the backing. Apply the patch to the prepared skin, pressing it firmly in place with your palm or fingers. Make sure it adheres completely and does not fold or wrinkle.
• Patch Placement: If you are using multiple patches, make sure to apply them to different areas to prevent skin irritation. Avoid applying the patch to areas that may be subject to pressure or friction from tight clothing or belts.
• Patch Duration: Nitro-Dur Patch is typically worn for 12 to 14 hours a day and removed for a 10 to 12-hour “patch-off” period to prevent tolerance from developing. The exact wearing and removal schedule will be determined by your healthcare provider and may vary based on your specific needs.
• Patch Rotation: To prevent skin irritation, it is important to rotate the application sites regularly. For example, if you applied the patch on your chest today, apply it to a different location tomorrow, and so on.
• Patch Removal: When it’s time to remove the patch, gently peel it off the skin. Fold the patch in half with the adhesive side inward and dispose of it properly. Clean the skin with mild soap and water to remove any adhesive residue.
• Patch Replacement: Apply a new patch at the scheduled time following the same process as mentioned above.

Remember, it is crucial to follow your healthcare provider’s instructions regarding the specific dosing regimen and any additional precautions associated with Nitro-Dur Patch. If you have any questions or concerns, consult your healthcare professional for clarification.

Other uses for this medicine

Nitro-Dur Patch, which contains nitroglycerin, is primarily used for the treatment of angina pectoris as explained earlier. However, it is important to note that using medications for off-label purposes should only be done under the guidance and prescription of a healthcare professional.

What special precautions should I follow?

Regarding special precautions associated with Nitro-Dur Patch, here are a few important considerations:

• Allergies: Inform your healthcare provider if you have a known allergy to nitroglycerin or any other nitrates. Allergic reactions to these substances can be serious and may include symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.
• Medical History: Provide a complete medical history to your healthcare provider, including any past or current medical conditions such as low blood pressure, recent heart attack, head injury, glaucoma, or liver disease. These conditions may affect the use of Nitro-Dur Patch or require special monitoring.
• Medications and Interactions: Inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Nitroglycerin can interact with other medications, including those used to treat erectile dysfunction (such as sildenafil, tadalafil, or vardenafil) and certain blood pressure medications, potentially causing serious side effects.
• Hypotension (Low Blood Pressure): Nitro-Dur Patch can cause a drop in blood pressure, leading to symptoms like lightheadedness, dizziness, or fainting. Use caution when getting up from a sitting or lying position, and notify your healthcare provider if you experience severe or persistent low blood pressure.
• Headaches: Headaches are a common side effect of nitroglycerin and can be more frequent when using Nitro-Dur Patch. While they often diminish over time, inform your healthcare provider if severe or persistent headaches occur.
• Alcohol and Grapefruit: Avoid consuming alcohol while using Nitro-Dur Patch, as it can enhance the drop in blood pressure. Additionally, grapefruit or grapefruit juice may interact with nitroglycerin and should be avoided or consumed in moderation.
• Pregnancy and Breastfeeding: Nitro-Dur Patch should be used during pregnancy or breastfeeding only if the potential benefits outweigh the risks. It is important to consult your healthcare provider to weigh the potential risks and benefits in these situations.

These are general precautions, but it’s essential to consult your healthcare provider or pharmacist for specific instructions and recommendations based on your individual circumstances and medical history. They will provide you with the most accurate and up-to-date information pertaining to the use of Nitro-Dur Patch.

What special dietary instructions should I follow?

Regarding special dietary instructions for Nitro-Dur Patch, there are no specific dietary restrictions associated with its use. However, it is generally advisable to follow a balanced and healthy diet that promotes cardiovascular health. This typically includes consuming a variety of fruits, vegetables, whole grains, lean proteins, and low-fat dairy products while limiting the intake of saturated fats, cholesterol, sodium, and added sugars. It’s important to discuss your dietary needs and restrictions with your healthcare provider or a registered dietitian for personalized recommendations.

What should I do if I forget a dose?

If you forget to apply a dose of Nitro-Dur Patch at the scheduled time, apply it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra patches to make up for a missed dose. Applying multiple patches at once can increase the risk of side effects and complications. If you have any concerns or questions about missed doses, it is best to consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Nitro-Dur Patch, like any medication, can cause side effects in some individuals. Not everyone who uses Nitro-Dur Patch will experience side effects, and the severity and frequency of side effects can vary. Here are some potential side effects associated with Nitro-Dur Patch:

• Headache: Headaches are a common side effect of nitroglycerin and can range from mild to severe. They often improve with continued use of the medication.
• Dizziness or lightheadedness: Nitroglycerin can cause a drop in blood pressure, leading to feelings of dizziness or lightheadedness. It is important to be cautious when changing positions, such as standing up quickly from a sitting or lying position.
• Flushing or warmth: Some individuals may experience flushing or warmth of the skin, often in the face, neck, or chest area.
• Skin irritation: The patch itself may cause skin irritation at the application site, including redness, itching, or rash. It is important to follow proper patch placement and rotation techniques to minimize skin irritation.
• Nausea or vomiting: Nitroglycerin can sometimes cause gastrointestinal symptoms such as nausea or vomiting.
• Hypotension (low blood pressure): Nitro-Dur Patch can lower blood pressure, which may cause symptoms such as weakness, fatigue, or fainting.
• Rapid heartbeat: Some individuals may experience an increase in heart rate while using Nitro-Dur Patch.

It is important to note that these are not all possible side effects. If you experience any persistent or severe side effects while using Nitro-Dur Patch, it is important to contact your healthcare provider for further evaluation and guidance. They can provide personalized advice and adjust your treatment if needed.

Additionally, be sure to read the medication’s package insert or consult your healthcare provider or pharmacist for a comprehensive list of side effects associated with Nitro-Dur Patch.

What should I know about storage and disposal of this medication?

• Storage: Store Nitro-Dur Patch at room temperature, away from excessive heat, moisture, and direct sunlight. Follow the specific storage instructions provided with the medication. Do not store it in the bathroom or any area with high humidity, as moisture can affect the patch’s effectiveness.
• Keep out of reach of children and pets: Nitro-Dur Patch should be stored in a secure location, out of the reach of children and pets. Accidental ingestion or application of the patch can be dangerous.
• Disposal: Unused or expired Nitro-Dur Patches should be properly disposed of according to local guidelines or instructions from your healthcare provider or pharmacist. It is generally recommended to fold the patch in half, sticky side inward, and dispose of it in a sealed container or appropriate disposal bag to prevent accidental exposure.

In case of emergency/overdose

If you believe you have used too much Nitro-Dur Patch or have accidentally ingested the medication, it is important to seek immediate medical attention or contact your local emergency services. Emergency signs of an overdose may include severe dizziness, fainting, rapid heartbeat, severe headache, or difficulty breathing.

What other information should I know?

• Regular follow-up appointments: It is common for healthcare providers to monitor the effectiveness of Nitro-Dur Patch and adjust the dosage as needed. Attend all scheduled follow-up appointments to discuss your progress and any concerns you may have.
• Nitrate-free intervals: Nitro-Dur Patch is usually prescribed with a nitrate-free interval, during which you do not wear a patch. This helps prevent the development of tolerance to the medication. Follow your healthcare provider’s instructions regarding the duration of the nitrate-free interval.
• Avoid sudden discontinuation: Do not stop using Nitro-Dur Patch abruptly without consulting your healthcare provider. They will provide guidance on gradually tapering off the medication, if necessary.
• Inform other healthcare providers: If you undergo any medical procedures or surgeries, inform the healthcare professionals involved that you are using Nitro-Dur Patch. Nitroglycerin can interact with certain medications and anesthesia agents, so it is important to provide this information to ensure safe and effective treatment.

Always read the medication’s package insert and consult your healthcare provider or pharmacist for complete and accurate information about Nitro-Dur Patch, including any specific instructions or precautions based on your individual circumstances.