Why is this medication prescribed?

Motegrity is a brand name for the medication Prucalopride. It is primarily prescribed to treat chronic idiopathic constipation (CIC) in adults. Chronic idiopathic constipation is a condition characterized by infrequent bowel movements and difficulty passing stools, and it is not associated with any underlying medical cause.

How should this medicine be used?

Here are general guidelines on how Motegrity should be used:

• Dosage: The usual recommended dose of Motegrity is 2 milligrams (mg) once daily. Your healthcare provider will determine the appropriate dosage for you based on your specific condition and medical history.
• Timing: Motegrity is usually taken with food, either before or after a meal. It is important to follow your healthcare provider’s instructions regarding when and how to take the medication.
• Swallowing: Motegrity tablets should be swallowed whole with a glass of water and should not be crushed, chewed, or broken.
• Consistency: Try to take Motegrity at the same time each day to maintain a consistent level of the medication in your system.
• Duration: The duration of treatment with Motegrity will be determined by your healthcare provider. It is essential to continue taking the medication as prescribed, even if you start to feel better, to maintain its effectiveness.
• Response: It may take a few days or even weeks for Motegrity to start working. Be patient and continue taking the medication as directed.
• Follow-up: Your healthcare provider may want to monitor your progress and make any necessary adjustments to your treatment plan during follow-up appointments.

It’s important to follow your healthcare provider’s instructions carefully and not exceed the prescribed dosage. If you have any questions or concerns about how to use Motegrity or if you experience any unusual side effects, contact your healthcare provider for guidance.

Please note that the information provided here is for general knowledge, and specific instructions for the use of Motegrity should be obtained from your healthcare provider or the medication’s packaging and labeling. It is essential to consult a healthcare professional for the most up-to-date information.

Other uses for this medicine

Motegrity (Prucalopride) is primarily prescribed to treat chronic idiopathic constipation (CIC) in adults and is not typically used for other purposes. It is specifically designed to address this condition and may not be suitable or effective for treating other medical issues. It’s important to use Motegrity only as directed by your healthcare provider.

What special precautions should I follow?

Special Precautions for Motegrity:

• Allergies: Before taking Motegrity, inform your healthcare provider if you have any known allergies to prucalopride or any other ingredients in the medication. Allergic reactions to medications can be severe and require immediate medical attention.
• Medical History: Your healthcare provider should be aware of your complete medical history, especially if you have any pre-existing medical conditions. Inform them about any history of heart problems, kidney problems, or severe gastrointestinal disorders.
• Medications: Make sure to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some medications may interact with Motegrity, potentially affecting its effectiveness or causing adverse effects.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Motegrity with your healthcare provider. The safety of this medication during pregnancy and breastfeeding is not well-established, and a healthcare provider will help weigh the potential benefits and risks.
• Cardiovascular Concerns: Motegrity can affect the electrical activity of the heart, potentially leading to heart rhythm abnormalities. If you have a history of heart problems or are taking medications that can affect heart rhythms, your healthcare provider should closely monitor you while on Motegrity.
• Gastrointestinal Disorders: Motegrity is intended for the treatment of chronic idiopathic constipation and should not be used to treat other gastrointestinal disorders without specific guidance from a healthcare provider.
• Alcohol: Avoid excessive alcohol consumption while taking Motegrity, as alcohol may increase the risk of certain side effects.
• Driving and Machinery: Motegrity may cause dizziness or drowsiness in some individuals. If you experience these side effects, avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how the medication affects you.

Always follow your healthcare provider’s instructions and recommendations regarding Motegrity. If you experience any concerning side effects or have questions about its use, consult your healthcare provider promptly. This information is meant to provide general guidance and should not replace personalized medical advice from a qualified healthcare professional.

What special dietary instructions should I follow?

There are no specific dietary restrictions that you need to follow when taking Motegrity (Prucalopride). However, it is generally recommended to take Motegrity with food, either before or after a meal, as this may help improve the absorption of the medication. Following a regular and balanced diet can also contribute to overall gastrointestinal health and may complement the treatment of chronic idiopathic constipation (CIC).

What should I do if I forget a dose?

If you forget to take a dose of Motegrity, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

What side effects can this medication cause?

Motegrity (Prucalopride) can cause side effects, although not everyone will experience them. Some common and less common side effects associated with Motegrity include:

Common Side Effects:

• Headache: Mild to moderate headaches may occur.
• Abdominal Pain: You may experience stomach discomfort or abdominal pain.
• Nausea: Some people may feel nauseated.
• Diarrhea: An increase in bowel movements or diarrhea can occur.

Less Common Side Effects:

• Fatigue: Feeling tired or having reduced energy levels.
• Dizziness: Some individuals may experience dizziness or lightheadedness.
• Dry Mouth: A dry feeling in the mouth may occur.
• Vomiting: In rare cases, vomiting may happen.
• Heart Palpitations: Prucalopride may affect the heart’s electrical activity, leading to heart palpitations or irregular heartbeats. This is more likely in individuals with certain pre-existing heart conditions.

Serious side effects are rare, but you should seek immediate medical attention if you experience any severe or unusual symptoms, such as:

• Severe Allergic Reactions: Symptoms can include difficulty breathing, hives, swelling of the face, lips, tongue, or throat. This is a medical emergency.
• Fainting or Loss of Consciousness: This may be related to changes in heart rhythm, so it should be taken seriously.
• Chest Pain or Rapid Heartbeat: This could indicate a serious cardiac issue.

It’s important to note that everyone’s response to medication can be different. Some people may experience none of these side effects, while others may experience several. If you experience bothersome or persistent side effects, or if you have concerns about the side effects of Motegrity, contact your healthcare provider. They can provide guidance on managing side effects or adjust your treatment plan if necessary.

As with any medication, it’s essential to weigh the potential benefits of Motegrity in managing chronic idiopathic constipation against the possible risks and side effects. Your healthcare provider can help you make an informed decision about its use based on your individual medical history and condition.

What should I know about storage and disposal of this medication?

Storage:

• Store as Directed: Keep Motegrity in its original packaging and store it at room temperature, away from excessive heat, moisture, and light. Follow any specific storage instructions provided on the medication packaging.
• Keep Out of Reach of Children: Store Motegrity in a location where it is out of the reach of children and pets. Medications should be kept in a secure and child-resistant container.
• Avoid Bathroom Storage: It’s generally not recommended to store medications in the bathroom, as the humidity and temperature changes can affect their stability.

Disposal:

• Dispose of Unused Medication: If you have unused or expired Motegrity, do not keep it indefinitely. Safely dispose of it to prevent accidental ingestion. Follow your local regulations for proper medication disposal.
• Community Take-Back Programs: Many communities have take-back programs or collection sites for safe medication disposal. Check with your local pharmacy or law enforcement agency for information on disposal options in your area.
• Do Not Flush: Do not flush Motegrity down the toilet unless specifically instructed to do so by your healthcare provider or on the medication’s labeling.

In case of emergency/overdose

If you suspect an overdose of Motegrity or experience severe adverse effects, seek immediate medical attention or contact a poison control center at 1-800-222-1222 in the United States. Overdose symptoms may include severe diarrhea, dehydration, dizziness, fainting, or irregular heart rhythms.

What other information should I know

• Follow Your Healthcare Provider’s Instructions: Always take Motegrity as prescribed by your healthcare provider. Do not alter the dosage or stop taking it without their guidance.
• Regular Follow-Up: Attend scheduled follow-up appointments with your healthcare provider to monitor your progress and discuss the effectiveness and safety of Motegrity.
• Medication Interactions: Inform your healthcare provider about all medications and supplements you are taking, as Motegrity may interact with certain drugs.
• Driving and Machinery: Be cautious if you experience dizziness or drowsiness while taking Motegrity, as it may impair your ability to drive or operate heavy machinery.
• Patient Information Leaflet: Read the patient information leaflet that comes with the medication for comprehensive details on usage, side effects, and precautions.
• Allergies and Hypersensitivity: If you experience signs of an allergic reaction (e.g., rash, itching, swelling, severe dizziness, difficulty breathing), seek immediate medical attention.

Remember that the information provided here is for general guidance, and it’s important to follow your healthcare provider’s specific instructions and recommendations regarding Motegrity. Additionally, medication guidelines may have changed, so consult a healthcare professional for the most up-to-date information.