Why is this medication prescribed?

Mirapex ER is a medication that is primarily prescribed to treat the symptoms of Parkinson’s disease and restless legs syndrome (RLS). Here’s why it is prescribed for these conditions:

• Parkinson’s Disease: Mirapex ER is commonly prescribed to manage the symptoms of Parkinson’s disease, a progressive neurological disorder. Parkinson’s disease is characterized by a deficiency of dopamine in the brain, which leads to motor symptoms such as tremors, stiffness, slowness of movement, and difficulty with balance and coordination. Mirapex ER is a dopamine agonist, which means it stimulates dopamine receptors in the brain, helping to alleviate some of these symptoms and improve motor function in individuals with Parkinson’s disease.
• Restless Legs Syndrome (RLS): Mirapex ER is also used to treat restless legs syndrome, a neurological disorder that causes an uncontrollable urge to move the legs, often accompanied by uncomfortable sensations such as tingling, crawling, or burning. This medication can help relieve the symptoms of RLS and improve the quality of sleep for individuals affected by this condition.

How should this medicine be used?

Here’s how Mirapex ER should be used:

• Dosage: The specific dosage of Mirapex ER will be determined by your healthcare provider and will depend on your medical condition, age, and other factors. It’s essential to follow your doctor’s instructions and not exceed the prescribed dose.
• Administration: Mirapex ER is usually taken orally, with or without food. The extended-release formulation means that the medication is released slowly over time, so it is typically taken once daily, usually in the evening.
• Do Not Crush or Chew: Swallow the Mirapex ER tablets whole. Do not crush, chew, or break them, as this may affect the extended-release properties of the medication.
• Timing: Take Mirapex ER at the same time each day to maintain a consistent level of the drug in your system.
• Adjustments: Your doctor may adjust the dosage over time to achieve the best therapeutic effect with the fewest side effects. It’s crucial to report any side effects or changes in your condition to your healthcare provider promptly.
• Duration: Continue taking Mirapex ER as long as prescribed by your doctor. Do not stop taking it abruptly without consulting your healthcare provider, as this could lead to a worsening of your symptoms.
• Side Effects: Be aware of potential side effects, including dizziness, drowsiness, nausea, and hallucinations. If you experience severe side effects or adverse reactions, contact your healthcare provider immediately.

It’s essential to have regular follow-up appointments with your healthcare provider while taking Mirapex ER to monitor your condition and adjust the treatment plan as needed. Always follow your doctor’s guidance and inform them of any other medications or supplements you are taking to avoid potential drug interactions.

Other uses for this medicine

While Mirapex ER is primarily used for Parkinson’s disease and restless legs syndrome, it is sometimes prescribed off-label for other conditions. These may include mood disorders like depression and bipolar disorder, as well as conditions involving neuropathic pain. The decision to use Mirapex ER for these off-label purposes should be made by a qualified healthcare provider who can assess the potential risks and benefits.

What special precautions should I follow?

As for special precautions to follow when taking Mirapex ER:

• Allergies: Inform your healthcare provider if you are allergic to pramipexole or any other ingredients in Mirapex ER.
• Medical History: Provide your healthcare provider with a complete medical history, including any history of kidney problems, mental/mood disorders (e.g., bipolar disorder, psychosis), and any unusual or allergic reactions to medications.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of taking Mirapex ER with your healthcare provider. The use of Mirapex ER during pregnancy should be carefully considered and monitored.
• Drowsiness and Dizziness: Mirapex ER may cause drowsiness and dizziness. Avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how the medication affects you.
• Alcohol: Limit or avoid alcohol consumption while taking Mirapex ER, as alcohol can enhance the sedative effects of the medication.
• Other Medications: Inform your healthcare provider of all medications, supplements, and herbal products you are taking to avoid potential drug interactions.
• Orthostatic Hypotension: Mirapex ER may cause a drop in blood pressure when changing positions (e.g., standing up quickly). Rise slowly from a sitting or lying position to minimize the risk of falls.
• Hallucinations: Some individuals taking Mirapex ER may experience hallucinations. If you experience unusual visions, sounds, or thoughts, contact your healthcare provider immediately.
• Withdrawal: Do not stop taking Mirapex ER abruptly without consulting your healthcare provider, as this can lead to withdrawal symptoms or worsening of symptoms.

Always follow your doctor’s instructions and keep regular follow-up appointments to monitor your progress and manage any potential side effects or concerns associated with Mirapex ER.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Mirapex ER. However, some individuals may experience nausea or upset stomach when taking it. Taking the medication with food may help alleviate these side effects. It’s best to follow your healthcare provider’s advice regarding the timing of doses with respect to meals.

What should I do if I forget a dose?

If you forget to take a dose of Mirapex ER:

• Timing: Take the missed dose as soon as you remember, but only if it’s not too close to your next scheduled dose. If your next dose is approaching, skip the missed dose and continue with your regular dosing schedule.
• Do Not Double Up: Do not take a double dose to make up for the missed one. Taking extra medication can increase the risk of side effects.
• Notify Your Healthcare Provider: If you frequently forget to take your medication or have difficulty adhering to your dosing schedule, discuss this with your healthcare provider. They may offer strategies or adjustments to help you stay on track with your treatment plan.

What side effects can this medication cause?

Mirapex ER (extended-release pramipexole) can cause a range of side effects, and it’s important to be aware of these potential effects while taking the medication. Keep in mind that not everyone will experience these side effects, and their severity can vary from person to person. Common side effects of Mirapex ER may include:

• Nausea: Nausea is one of the most common side effects of Mirapex ER. Taking the medication with food or as directed by your healthcare provider may help reduce this symptom.
• Dizziness: Many individuals experience dizziness when taking Mirapex ER. To minimize the risk of falls, it’s essential to get up slowly from sitting or lying positions.
• Drowsiness: Some people may feel drowsy or have episodes of sudden sleep onset while taking Mirapex ER. Avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how the medication affects you.
• Hallucinations: Hallucinations, which involve seeing, hearing, or feeling things that are not there, can occur in some individuals taking Mirapex ER. These hallucinations are more common in elderly patients.
• Fatigue: Feeling tired or fatigued is another possible side effect. It’s important to get enough rest and avoid activities that could be dangerous if you’re excessively tired.
• Orthostatic Hypotension: Mirapex ER can cause a drop in blood pressure when changing positions (e.g., standing up quickly). Rising slowly can help minimize the risk of dizziness and falls.
• Swelling of Legs and Feet: Some individuals may experience swelling of the legs and feet, known as peripheral edema, as a side effect of Mirapex ER.
• Abnormal Movements: In rare cases, Mirapex ER may cause or worsen certain abnormal movements, including dyskinesia (involuntary muscle movements) or dystonia (sustained muscle contractions).
• Impulse Control Disorders: There have been reports of impulse control disorders, such as compulsive gambling, binge eating, and increased sexual desire or behavior, in individuals taking Mirapex ER. If you notice any unusual changes in behavior or urges, inform your healthcare provider.
• Psychiatric Symptoms: Pramipexole, the active ingredient in Mirapex ER, has been associated with psychiatric symptoms such as mood changes, including depression and suicidal thoughts. Be vigilant for changes in mood and report them to your healthcare provider.

It’s important to remember that not everyone will experience these side effects, and some individuals may experience side effects not listed here. Additionally, the severity and duration of side effects can vary. If you experience any side effects while taking Mirapex ER, it’s crucial to discuss them with your healthcare provider. They can provide guidance on managing side effects, adjust your dosage if necessary, or explore alternative treatments if the side effects are severe or intolerable. Do not stop taking Mirapex ER without consulting your healthcare provider, as abruptly discontinuing the medication can lead to withdrawal symptoms or worsening of symptoms.

What should I know about storage and disposal of this medication?

Storage:

• Store Properly: Keep Mirapex ER in a tightly closed container at room temperature, away from moisture, heat, and direct sunlight. Do not store it in the bathroom.
• Childproofing: Ensure that the medication is stored in a location out of reach of children and pets. Pramipexole can be dangerous if ingested by a child or animal.
• Avoid Excessive Humidity: Protect the medication from excessive moisture, which can affect its stability.

Disposal:

• Follow Local Guidelines: Dispose of unused or expired Mirapex ER tablets according to local guidelines and regulations for medication disposal. Do not flush them down the toilet or throw them in the trash, as this may be harmful to the environment.
• Medication Take-Back Programs: Many communities and pharmacies offer medication take-back programs, where you can safely dispose of unused or expired medications. Check with your local pharmacy or healthcare provider for information on such programs in your area.

In case of emergency/overdose

In the case of an emergency or suspected overdose of Mirapex ER, take the following steps:

• Seek Immediate Medical Attention: Contact your local poison control center (1-800-222-1222 in the United States) or go to the nearest emergency room or healthcare facility.
• Symptom Management: If possible, provide healthcare professionals with information about the type and amount of Mirapex ER ingested, as well as any other relevant details.
• Do Not Delay: Time is crucial in cases of overdose, so do not hesitate to seek medical help.

What other information should I know

• Regular Follow-Up: Attend all scheduled follow-up appointments with your healthcare provider to monitor your response to Mirapex ER and make any necessary adjustments to your treatment plan.
• Do Not Share Medication: Do not share Mirapex ER with others, even if they have similar symptoms or conditions. The medication should only be taken under the guidance of a healthcare provider.
• Keep a Medication List: Maintain a list of all the medications, including Mirapex ER, that you are taking and share this list with your healthcare providers, including dentists and pharmacists. This information can help prevent potential drug interactions.
• Patient Information Leaflet: Read the patient information leaflet provided by your pharmacist when you receive your prescription. It contains essential information about the medication, including potential side effects and dosing instructions.
• Dosing Schedule: Stick to the prescribed dosing schedule for Mirapex ER and do not change your dose without consulting your healthcare provider.
• Driving and Operating Machinery: Be cautious when performing activities that require mental alertness, such as driving or operating heavy machinery, as Mirapex ER can cause dizziness and drowsiness.
• Report Side Effects: If you experience any unusual or severe side effects while taking Mirapex ER, contact your healthcare provider promptly.

Always follow your healthcare provider’s instructions regarding the use of Mirapex ER and consult them with any questions or concerns you may have about the medication.