WARNING

Mifepristone, commonly known by its brand name Mifeprex, is a medication used for medical abortion, also referred to as medication abortion or the abortion pill. While it is generally safe and effective when used as prescribed, there are potential risks and side effects associated with its use. Here is a brief overview of the risks of taking Mifepristone:

• Incomplete Abortion: In some cases, Mifepristone may not terminate the pregnancy completely, leading to an incomplete abortion. This may require additional medical intervention or a surgical procedure to complete the abortion.
• Heavy Bleeding: Bleeding is a normal part of the abortion process, but it can be heavy and prolonged. Excessive bleeding may require medical attention.
• Cramping and Pain: Users often experience uterine cramping and abdominal pain, which can be discomforting.
• Infection: There is a risk of infection following a medical abortion. It’s crucial to follow the prescribed instructions for care and follow-up appointments to reduce this risk.
• Allergic Reactions: While rare, some individuals may experience allergic reactions to Mifepristone, leading to symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical help if this occurs.
• Ectopic Pregnancy: Mifepristone does not treat ectopic pregnancies (pregnancies outside the uterus). Using it when you have an ectopic pregnancy can be dangerous.
• Emotional and Psychological Impact: Undergoing an abortion can have emotional and psychological effects on individuals. It’s important to have access to emotional support and counseling if needed.
• Legal and Accessibility Issues: Access to Mifepristone may be restricted in certain regions due to legal, political, or logistical factors, making it difficult for some individuals to obtain the medication safely.

It’s crucial for individuals considering Mifepristone for a medical abortion to consult with a healthcare provider, follow the prescribed dosage and instructions, and have access to appropriate medical care and support throughout the process. This medication should only be used under the guidance of a qualified healthcare professional.

Why is this medication prescribed?

Mifepristone, commonly known by its brand name Mifeprex, is prescribed for a specific medical purpose. Mifepristone is prescribed to induce a medical abortion, which is a non-surgical method of terminating a pregnancy. It is typically used in the early stages of pregnancy, up to 10 weeks gestation. This medication works by blocking the hormone progesterone, which is necessary for the pregnancy to continue. It is often used in combination with another medication called misoprostol to complete the abortion process.

How should this medicine be used?

Using Mifepristone safely and effectively requires strict adherence to medical guidance and instructions. Here’s a general outline of how it should be used:

• Medical Supervision: Mifepristone should only be prescribed and administered under the supervision of a qualified healthcare provider, typically in a healthcare facility or clinic.
• Timing: It is most effective when used early in pregnancy, up to 10 weeks gestation.
• Dosage: The typical dosage is a single 200-milligram tablet of Mifepristone, which is taken orally in the presence of a healthcare provider.
• Follow-up: After taking Mifepristone, you will usually return to the healthcare provider’s office within 24 to 48 hours to receive a second medication called misoprostol, which helps to expel the pregnancy.
• Monitoring: During the abortion process, you will be monitored for any side effects, bleeding, or complications.
• Bleeding and Cramping: After taking the second medication (misoprostol), you will experience heavy bleeding and cramping as your body expels the pregnancy. This is a normal part of the process.
• Follow-up Appointment: A follow-up appointment with your healthcare provider is essential, usually within 7-14 days after taking Mifepristone, to ensure the abortion is complete and to address any potential complications.

It’s crucial to strictly follow the instructions provided by your healthcare provider and to seek medical attention promptly if you experience severe or unusual symptoms during the abortion process. Mifepristone should only be used for its prescribed purpose and should not be self-administered without medical guidance. Additionally, the availability and legality of Mifepristone may vary by region, so it’s important to consult with a healthcare provider for guidance specific to your location.

Other uses for this medicine

Mifepristone is primarily approved for medical abortion. However, in some cases, it may also be used for other medical purposes under the guidance of a healthcare provider, such as:

• Cushing’s Syndrome: Mifepristone can be used to treat Cushing’s syndrome, a hormonal disorder characterized by an excess of cortisol in the body.
• Fibroids: In some cases, Mifepristone may be considered for the treatment of uterine fibroids.
• Research: Mifepristone is also used in medical research, but this is not for self-administration and should only be done in a controlled, research setting.

What special precautions should I follow?

As for special precautions when using Mifepristone (Mifeprex), here are some important considerations:

• Medical Supervision: Mifepristone should always be prescribed and administered by a healthcare provider in a clinical setting. Self-administration is not recommended.
• Pregnancy Test: Before using Mifepristone for medical abortion, a confirmed pregnancy test should be conducted to ensure that it is appropriate for your situation.
• Patient Information: Be sure to provide your healthcare provider with a complete medical history, including any allergies, current medications, and underlying medical conditions.
• Follow Instructions: Strictly follow the instructions provided by your healthcare provider for taking Mifepristone and any subsequent medications (such as misoprostol) as part of the abortion process.
• Emergency Contact: Have access to emergency medical care and contact information in case you experience severe or unusual symptoms during the abortion process.
• Follow-up Appointment: Attend the follow-up appointment scheduled by your healthcare provider to ensure the abortion is complete and to address any concerns or complications.
• Legal Considerations: Be aware of the legal and regulatory status of Mifepristone in your region, as it may vary by country or state.
• Emotional Support: Seek emotional support or counseling if needed, as undergoing a medical abortion can have emotional and psychological effects.

Always consult with a healthcare provider for personalized guidance and to ensure safe and appropriate use of Mifepristone for your specific situation.

What special dietary instructions should I follow?

Mifepristone is typically taken as a single, prescribed dose in a healthcare provider’s office as part of a medical abortion procedure. It is not a medication that you take at home with dietary instructions or multiple doses over time. Therefore, there are usually no specific dietary instructions associated with its use.

What should I do if I forget a dose?

Since Mifepristone is administered as a single, supervised dose, there is no concern about forgetting a dose. It’s administered in a clinical setting, and you should not attempt to self-administer this medication. You will receive the dose under the direct supervision of your healthcare provider as part of the medical abortion procedure.

What side effects can this medication cause?

Mifepristone (Mifeprex), like any medication, can cause side effects. It’s essential to be aware of these potential side effects when undergoing a medical abortion. Not everyone will experience these side effects, and their severity can vary from person to person. Common side effects of Mifepristone may include:

• Vaginal Bleeding: This is a normal part of the abortion process and can be heavy. Bleeding may last for several days or even weeks.
• Abdominal Pain and Cramping: Many individuals experience uterine cramping and abdominal discomfort during and after taking Mifepristone.
• Nausea and Vomiting: Some people may feel nauseous or even vomit after taking the medication.
• Diarrhea: Diarrhea can occur as a side effect.
• Fatigue: Feeling tired or fatigued is common during the abortion process.
• Headache: Some individuals may experience headaches.
• Dizziness: Dizziness or lightheadedness can occur.
• Fever and Chills: In some cases, a low-grade fever and chills may develop.

It’s important to remember that these side effects are typically temporary and should subside as the abortion process progresses. However, if you experience any of the following more severe or concerning side effects, you should seek immediate medical attention:

• Heavy Bleeding: Soaking through two or more sanitary pads per hour for two consecutive hours.
• Severe Abdominal Pain: Pain that is not relieved by over-the-counter pain medications.
• Fever above 100.4°F (38°C): A high fever could indicate infection.
• Signs of an Allergic Reaction: Such as rash, itching, swelling of the face or throat, severe dizziness, or difficulty breathing.

Additionally, it’s essential to attend the follow-up appointment scheduled by your healthcare provider to ensure the abortion is complete and to address any concerns or complications.

Every individual’s experience with Mifepristone can be different, and not everyone will experience severe side effects. Your healthcare provider can provide you with personalized guidance and address any questions or concerns you may have about the medication and its potential side effects.

What should I know about storage and disposal of this medication?

Storage:

• Storage Temperature: Store Mifepristone at room temperature, between 68°F to 77°F (20°C to 25°C).
• Keep Out of Reach of Children: Ensure that the medication is stored in a secure place away from the reach of children and pets.

Disposal:

• Follow Local Regulations: Dispose of unused Mifepristone tablets according to local regulations and guidelines. You can consult your healthcare provider or pharmacist for specific disposal instructions.

In case of emergency/overdose

In case of an emergency or suspected overdose with Mifepristone, seek immediate medical attention. Signs of an overdose or serious adverse reactions may include severe vaginal bleeding, severe abdominal pain, high fever, or other severe symptoms.

What other information should I know

• Follow Instructions Carefully: Always follow the instructions provided by your healthcare provider for the administration of Mifepristone and any other medications given as part of the medical abortion procedure.
• Follow-up Appointment: Attend the follow-up appointment scheduled by your healthcare provider. This is essential to ensure that the abortion is complete and to address any concerns or complications.
• Seek Emotional Support: Undergoing a medical abortion can have emotional and psychological effects. Seek emotional support, counseling, or assistance from healthcare professionals if needed.
• Legal and Regulatory Considerations: Be aware of the legal and regulatory status of Mifepristone in your region, as it may vary by country or state. Access to Mifepristone and medical abortion may also be subject to specific regulations and requirements.
• Allergic Reactions: Be vigilant for signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, and seek immediate medical help if such reactions occur.
• Follow Healthcare Provider’s Advice: Your healthcare provider is the best source of information regarding the use of Mifepristone for your specific situation. If you have any questions or concerns, do not hesitate to consult them for guidance.
• Emergency Contact: Ensure you have access to emergency medical care and contact information during the medical abortion process.

Remember that Mifepristone should only be used under the supervision of a qualified healthcare provider and for its prescribed purposes, which include medical abortion and, in some cases, the treatment of Cushing’s syndrome. The information provided here is for general guidance, and individual circumstances may vary, so consult with your healthcare provider for personalized information and advice.