WARNING

Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, inflammation, and fever. Like all medications, it carries certain risks and potential side effects. Here are some of the key risks associated with taking mefenamic acid:

• Gastrointestinal Issues: NSAIDs, including mefenamic acid, can irritate the stomach lining and increase the risk of ulcers, bleeding, and gastrointestinal discomfort. This risk is higher in individuals with a history of stomach problems or those taking the medication for an extended period.
• Cardiovascular Risks: NSAIDs have been associated with an increased risk of heart attack and stroke, especially when used at high doses or for prolonged periods. This risk may be higher in individuals with pre-existing heart conditions.
• Kidney Function: Mefenamic acid can affect kidney function, potentially leading to fluid retention and increased blood pressure. People with kidney problems should use this medication with caution and under medical supervision.
• Allergic Reactions: Some individuals may experience allergic reactions to mefenamic acid, such as skin rashes, itching, swelling, or difficulty breathing. Seek immediate medical attention if you experience any of these symptoms.
• Bleeding: Mefenamic acid can increase the risk of bleeding, especially in the gastrointestinal tract. This risk is higher for people with bleeding disorders or those taking blood-thinning medications.
• Liver Effects: Rarely, mefenamic acid may lead to liver problems, including liver inflammation. If you notice symptoms like yellowing of the skin or eyes (jaundice) or dark urine, contact a healthcare provider.
• Pregnancy and Nursing: Mefenamic acid is generally not recommended during pregnancy, especially in the third trimester, as it may harm the unborn baby. It can also pass into breast milk and affect nursing infants.
• Interactions: Mefenamic acid can interact with other medications you may be taking, potentially affecting their effectiveness or increasing side effects.

To minimize the risks associated with mefenamic acid, it’s crucial to use it as directed by your healthcare provider, at the lowest effective dose and for the shortest duration necessary to manage your symptoms. Always consult with a healthcare professional before starting or stopping any medication, especially if you have underlying medical conditions or are taking other drugs. If you experience any unusual or severe side effects while taking mefenamic acid, seek medical attention promptly.

Why is this medication prescribed?

Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) prescribed for various medical conditions to relieve pain, inflammation, and fever. It is typically prescribed for the following reasons:

• Pain Relief: Mefenamic acid is used to alleviate mild to moderate pain, such as menstrual cramps, dental pain, musculoskeletal pain, and headaches.
• Menstrual Pain: It is often prescribed to manage the pain and discomfort associated with menstrual periods, including dysmenorrhea (menstrual cramps).
• Inflammation: Mefenamic acid can reduce inflammation in conditions like osteoarthritis and rheumatoid arthritis, helping to relieve joint pain and swelling.
• Fever Reduction: It can be used to lower fever in individuals with fever-inducing illnesses or infections.

How should this medicine be used?

Here are some general guidelines for how to use mefenamic acid:

• Dosage: The recommended dosage of mefenamic acid varies depending on the condition being treated. Always follow your healthcare provider’s instructions and the instructions on the medication label. Do not exceed the prescribed dose.
• Administration: Mefenamic acid is usually taken by mouth as a tablet or capsule. It can be taken with or without food, but taking it with food or milk may help reduce the risk of stomach upset.
• Timing: Take mefenamic acid at regular intervals as directed by your doctor. It is typically taken every 6 to 8 hours, but the exact dosing schedule may vary.
• Avoid Alcohol: It’s advisable to avoid alcohol while taking mefenamic acid, as it can increase the risk of stomach irritation and bleeding.
• Duration: Use mefenamic acid for the shortest duration necessary to relieve your symptoms. If you need to take it for an extended period, your healthcare provider may monitor you for potential side effects.
• Allergies: If you are allergic to aspirin or other NSAIDs, inform your healthcare provider before taking mefenamic acid.
• Precautions: Inform your healthcare provider of any medical conditions you have, especially if you have a history of stomach ulcers, bleeding disorders, heart disease, kidney problems, or asthma.
• Interaction: Inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential drug interactions.
• Pregnancy and Breastfeeding: Mefenamic acid is generally not recommended during the third trimester of pregnancy and while breastfeeding, unless specifically advised by a healthcare provider.

Always consult with your healthcare provider before starting or stopping mefenamic acid, and promptly report any unusual or severe side effects. This information serves as a general guideline, and individual dosing and usage instructions may vary based on your specific medical condition and needs.

Other uses for this medicine

While Mefenamic acid is primarily prescribed for pain, inflammation, and menstrual cramps, it may have other off-label uses that your healthcare provider could consider depending on your individual medical condition. However, it’s important to note that any off-label use should be discussed with and approved by a qualified healthcare professional, as it may carry risks and potential side effects that need to be carefully considered. Always consult with your healthcare provider before using Mefenamic acid for any purpose other than those for which it is approved.

What special precautions should I follow?

When using mefenamic acid, it’s important to take special precautions to ensure its safe and effective use:

• Medical History: Inform your healthcare provider about your complete medical history, including any allergies, pre-existing medical conditions, and a history of gastrointestinal problems, ulcers, bleeding disorders, heart disease, kidney issues, or asthma.
• Medication Interaction: Discuss all the medications, supplements, and herbal products you are taking with your healthcare provider to avoid potential drug interactions.
• Dosage: Take mefenamic acid exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or use it for an extended period without medical guidance.
• Gastrointestinal Protection: If you have a history of gastrointestinal problems, your healthcare provider may prescribe medications to protect your stomach lining while taking mefenamic acid.
• Monitoring: If you need to use mefenamic acid for an extended duration, your healthcare provider may periodically monitor you for any potential side effects or complications.
• Alcohol: Avoid or limit alcohol consumption while taking mefenamic acid, as alcohol can increase the risk of stomach irritation and bleeding.
• Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Mefenamic acid is generally not recommended during the third trimester of pregnancy and while breastfeeding unless specifically advised by a healthcare provider.
• Allergic Reactions: Be aware of any signs of an allergic reaction, such as skin rashes, itching, swelling, or difficulty breathing, and seek immediate medical attention if you experience these symptoms.

Always follow your healthcare provider’s instructions carefully and communicate any concerns or questions you may have about mefenamic acid. This medication should be used under their guidance to ensure your safety and well-being.

What special dietary instructions should I follow?

There are no specific dietary instructions that you need to follow for mefenamic acid. However, you can take it with or without food, and taking it with food or milk may help reduce the risk of stomach upset or irritation. If you find that mefenamic acid upsets your stomach, you can try taking it with a meal or a snack.

What should I do if I forget a dose?

If you forget to take a dose of mefenamic acid, here are some general guidelines:

• Regular Dosing Schedule: If it’s close to the time for your next scheduled dose, simply skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
• Set a Reminder: To avoid missing doses, you can set an alarm or reminder on your phone or use a pill organizer to help you keep track of your medication schedule.
• Consult Your Healthcare Provider: If you are unsure about what to do when you miss a dose or if you frequently forget doses, it’s a good idea to contact your healthcare provider. They can provide guidance specific to your situation and may adjust your dosing schedule if necessary.

What side effects can this medication cause?

Mefenamic acid, like other nonsteroidal anti-inflammatory drugs (NSAIDs), can cause a range of side effects. Not everyone will experience these side effects, and some people may have a higher risk than others. Common side effects of mefenamic acid include:

• Gastrointestinal Issues: NSAIDs, including mefenamic acid, can irritate the stomach lining, leading to symptoms such as indigestion, heartburn, nausea, vomiting, abdominal pain, and diarrhea. This can sometimes result in more serious gastrointestinal problems like ulcers or bleeding, although these are less common.
• Dizziness: Some individuals may experience dizziness or lightheadedness while taking mefenamic acid. Avoid activities that require mental alertness, such as driving, until you know how the medication affects you.
• Headache: Headaches are a potential side effect of mefenamic acid.
• Skin Reactions: In rare cases, mefenamic acid can cause skin reactions, such as rashes, itching, or hives. If you notice any unusual skin changes, contact your healthcare provider.
• Fluid Retention: Mefenamic acid may lead to fluid retention and swelling in some individuals, particularly those with pre-existing heart or kidney conditions.
• High Blood Pressure: In some cases, NSAIDs like mefenamic acid can increase blood pressure, which may be a concern for individuals with hypertension.
• Liver Effects: Although rare, mefenamic acid may affect liver function and lead to symptoms like jaundice (yellowing of the skin or eyes) or dark urine. Seek medical attention if you experience these symptoms.
• Kidney Function: NSAIDs can impact kidney function, potentially leading to kidney problems. This risk is higher in individuals with pre-existing kidney issues.
• Allergic Reactions: Allergic reactions to mefenamic acid are possible but uncommon. Symptoms may include skin rashes, itching, swelling, difficulty breathing, or severe dizziness. Seek immediate medical attention if you experience these symptoms.
• Cardiovascular Events: Like other NSAIDs, mefenamic acid may increase the risk of cardiovascular events such as heart attack or stroke, especially when used at high doses or for prolonged periods. This risk may be higher in individuals with pre-existing heart conditions.

It’s important to take mefenamic acid as directed by your healthcare provider and at the lowest effective dose for the shortest duration necessary to manage your symptoms. Be aware of any potential side effects, and if you experience severe or unusual symptoms while taking mefenamic acid, seek medical attention promptly. Additionally, discuss any concerns or questions about this medication with your healthcare provider, especially if you have underlying medical conditions or are taking other medications.

What should I know about storage and disposal of this medication?

Storage:

• Store at Room Temperature: Keep mefenamic acid at room temperature, away from excessive heat and moisture. Do not freeze it.
• Keep Out of Reach of Children: Store the medication out of reach of children and pets to prevent accidental ingestion.
• Original Container: Keep mefenamic acid in its original container with the lid tightly closed. This helps protect the medication from moisture and air exposure.
• Avoid Sunlight: Store the medication away from direct sunlight.

Disposal:

• Dispose of Safely: Dispose of any unused or expired mefenamic acid properly. Do not flush it down the toilet or pour it down the drain, unless specifically instructed to do so. Check with your local pharmacy or healthcare provider for guidance on safe medication disposal in your area.
• Medication Take-Back Programs: Many communities have medication take-back programs that allow you to safely return unused medications. Check with your local pharmacy or law enforcement agency for information on these programs.

In case of emergency/overdose

In the event of an emergency or suspected overdose of mefenamic acid, take the following steps:

• Seek Medical Help: Call emergency services (911 in the United States) or your local emergency number immediately if you or someone else has taken a large dose of mefenamic acid or is experiencing severe symptoms.
• Poison Control Center: Contact your nearest poison control center for guidance on what to do next. Be ready to provide information about the medication, the dose taken, and the person’s symptoms.

What other information should I know

• Follow Your Healthcare Provider’s Instructions: Always take mefenamic acid as prescribed by your healthcare provider. Do not alter the dosage or frequency without their guidance.
• Monitor for Side Effects: Be aware of potential side effects of mefenamic acid and report any unusual or severe symptoms to your healthcare provider.
• Avoid Alcohol: It’s advisable to limit or avoid alcohol while taking mefenamic acid, as it can increase the risk of stomach irritation and bleeding.
• Inform Healthcare Providers: Always inform your healthcare providers, including dentists and surgeons, that you are taking mefenamic acid, as it may interact with other medications or affect medical procedures.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of mefenamic acid with your healthcare provider. It’s generally not recommended during the third trimester of pregnancy.
• Allergies: If you have a known allergy to mefenamic acid, other NSAIDs, or aspirin, inform your healthcare provider before starting the medication.
• Regular Check-Ups: If you are using mefenamic acid long-term, your healthcare provider may schedule regular check-ups to monitor your condition and assess any potential side effects.

Always keep your healthcare provider informed about your medication use, and follow their guidance for safe and effective treatment with mefenamic acid or any other medication.