WARNING

Ketorolac nasal spray is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve moderate to severe pain. While it can be effective for short-term pain relief, there are certain risks associated with its use. Here are some of the potential risks of taking Ketorolac nasal spray:

• Gastrointestinal Effects: NSAIDs, including Ketorolac, can increase the risk of stomach ulcers, bleeding, and perforation. These risks are particularly higher for individuals with a history of gastrointestinal disorders, such as ulcers or gastrointestinal bleeding.
• Cardiovascular Risks: Ketorolac may increase the risk of heart attack, stroke, and other cardiovascular events, especially when used for prolonged periods or at high doses. This risk is higher for individuals with pre-existing heart conditions or those who have had cardiovascular problems in the past.
• Kidney Damage: Ketorolac can cause kidney problems, including reduced kidney function and kidney failure. Individuals with pre-existing kidney conditions or those at risk of dehydration should be cautious when using Ketorolac.
• Allergic Reactions: Some individuals may be allergic to Ketorolac or other NSAIDs. Allergic reactions can range from mild symptoms like rashes to severe reactions like difficulty breathing or anaphylaxis, a life-threatening condition.
• Interaction with Other Medications: Ketorolac may interact with certain medications, including other NSAIDs, blood thinners, diuretics, and certain antidepressants. These interactions can increase the risk of side effects or reduce the effectiveness of either medication.
• Nasal Effects: As Ketorolac is administered as a nasal spray, it may cause nasal irritation, stinging, or burning sensations. Some individuals may also experience headaches or nosebleeds.

It’s important to note that this is not an exhaustive list of risks, and individuals considering the use of Ketorolac nasal spray should consult with a healthcare professional. They can provide a comprehensive assessment of your medical history and help weigh the potential benefits against the risks to determine the most suitable course of action.

Why is this medication prescribed?

Ketorolac nasal spray is prescribed to provide short-term relief from moderate to severe pain. It is commonly used in situations where oral NSAIDs may not be appropriate or feasible, such as when a patient is unable to swallow medication due to vomiting or postoperative conditions. Ketorolac nasal spray is often prescribed for the following purposes:

• Postoperative Pain: It is frequently used to manage pain after surgical procedures, including dental surgery, orthopedic surgery, and minor surgeries.
• Migraine: Ketorolac nasal spray can be prescribed for the treatment of moderate to severe migraines. It helps to alleviate the pain and associated symptoms during an acute migraine attack.
• Acute Pain: It may be prescribed for the short-term relief of other types of acute pain, such as musculoskeletal injuries, renal colic, or pain associated with other medical conditions.
• Obstetric Use: In some cases, Ketorolac nasal spray may be used for a limited duration for pain management during labor or after cesarean section delivery.

How should this medicine be used?

Ketorolac nasal spray should be used exactly as prescribed by your healthcare professional. It is important to follow the recommended dosage and instructions provided. Here are some general guidelines for using Ketorolac nasal spray:

• Priming: Before using the nasal spray for the first time or if it has not been used for several days, it may require priming. Priming involves spraying the medication into the air until a fine mist is produced. Follow the specific priming instructions provided with the nasal spray.
• Positioning: Stand or sit upright with your head tilted slightly forward. Keep your head in a position that allows the nasal spray to be properly administered.
• Administration: Hold the bottle with your thumb at the bottom and your index and middle fingers on the sides of the nozzle. Insert the nozzle into one nostril, aiming it away from the center of your nose. Close the other nostril by pressing your finger against it. Breathe in gently through your nose while simultaneously pressing down on the pump to release the spray. Avoid tilting your head back during administration.
• Repeat: If directed by your healthcare professional, repeat the process in the other nostril to ensure both nostrils receive the medication.
• Clean-up: After each use, wipe the nozzle with a clean tissue or cloth to prevent contamination. Replace the cap to keep the nozzle clean and protect the medication from exposure.

It is important to strictly adhere to the prescribed dosage and frequency. Do not exceed the recommended dose, as it may increase the risk of side effects. If you have any questions or concerns regarding the proper use of Ketorolac nasal spray, consult your healthcare professional for guidance.

Other uses for this medicine

Ketorolac nasal spray is primarily prescribed for the management of short-term pain, postoperative pain, migraines, and acute pain. However, it’s important to note that the approved uses of Ketorolac nasal spray may vary depending on the country and regulatory guidelines. Therefore, it’s crucial to consult with a healthcare professional to determine the specific approved uses in your region.

What special precautions should I follow?

As for special precautions associated with Ketorolac nasal spray, here are some important points to consider:

• Allergic Reactions: If you have a known allergy to Ketorolac or other NSAIDs, it is essential to avoid using Ketorolac nasal spray. Allergic reactions to NSAIDs can range from mild symptoms like rashes and itching to severe reactions like difficulty breathing or anaphylaxis. Seek immediate medical attention if you experience any signs of an allergic reaction.
• Gastrointestinal Effects: Ketorolac can increase the risk of stomach ulcers, bleeding, and perforation, particularly in individuals with a history of gastrointestinal disorders. It is important to inform your healthcare professional if you have a history of ulcers, gastrointestinal bleeding, or other digestive system conditions.
• Cardiovascular Risks: Ketorolac, like other NSAIDs, may increase the risk of heart attack, stroke, and other cardiovascular events. This risk may be higher in individuals with pre-existing heart conditions, high blood pressure, or those who have had cardiovascular problems in the past. Inform your healthcare professional about your medical history, especially regarding cardiovascular health.
• Kidney Function: Ketorolac can cause kidney problems, including reduced kidney function and kidney failure. Individuals with pre-existing kidney conditions or those at risk of dehydration should use Ketorolac nasal spray with caution. It is important to stay well hydrated and report any signs of kidney problems, such as changes in urine output or color, to your healthcare professional.
• Medication Interactions: Ketorolac may interact with other medications, including other NSAIDs, blood thinners, diuretics, and certain antidepressants. These interactions can increase the risk of side effects or reduce the effectiveness of either medication. Inform your healthcare professional about all the medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions.
• Pregnancy and Breastfeeding: The use of Ketorolac nasal spray during pregnancy or breastfeeding is generally not recommended. It is crucial to consult with a healthcare professional to assess the risks and benefits before using Ketorolac nasal spray during these periods.

These are some general precautions associated with Ketorolac nasal spray. However, it’s important to remember that specific precautions may vary, and it’s always advisable to consult with a healthcare professional who can provide personalized advice based on your medical history and individual circumstances.

What special dietary instructions should I follow?

Ketorolac nasal spray does not have any specific dietary instructions. You can generally take it with or without food. However, it’s always a good idea to follow a balanced and healthy diet while using any medication to support overall well-being.

What should I do if I forget a dose?

If you forget to take a dose of Ketorolac nasal spray, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

What side effects can this medication cause?

Ketorolac nasal spray, like any medication, can cause side effects. Not everyone who uses Ketorolac nasal spray will experience side effects, and their severity can vary from person to person. It’s important to be aware of potential side effects and promptly report any unusual or concerning symptoms to your healthcare professional. Here are some common side effects associated with Ketorolac nasal spray:

• Nasal Effects: Ketorolac nasal spray can cause nasal irritation, stinging, or burning sensations. Some individuals may also experience dryness, itching, or discomfort in the nose. Nosebleeds can occur, although they are less common.
• Headache: Headaches are a common side effect of Ketorolac nasal spray. They are usually temporary and may resolve on their own. If persistent or severe, it’s important to inform your healthcare professional.
• Gastrointestinal Effects: Ketorolac and other NSAIDs can cause gastrointestinal side effects. These may include stomach pain, nausea, indigestion, diarrhea, or constipation. In some cases, there may be an increased risk of stomach ulcers, bleeding, or perforation.
• Dizziness or Drowsiness: Some individuals may experience dizziness or drowsiness while using Ketorolac nasal spray. It is important to exercise caution when engaging in activities that require alertness, such as driving or operating machinery.
• Allergic Reactions: Although rare, allergic reactions to Ketorolac nasal spray can occur. Allergic symptoms may include skin rashes, itching, swelling, difficulty breathing, or anaphylaxis, which is a severe and potentially life-threatening reaction. Seek immediate medical attention if you experience any signs of an allergic reaction.
• Kidney and Liver Effects: Ketorolac can affect kidney function and may cause kidney problems, such as reduced kidney function or kidney failure. It can also affect liver function, although these side effects are relatively rare.

It’s important to note that this is not an exhaustive list of side effects, and others may occur. Additionally, the severity and occurrence of side effects can vary among individuals. If you experience any unusual or bothersome side effects while using Ketorolac nasal spray, it is recommended to consult your healthcare professional for evaluation and guidance.

What should I know about storage and disposal of this medication?

Storage of Ketotifen Ophthalmic:

• Ketorolac nasal spray should be stored at room temperature, away from excessive heat and moisture.
• Keep the bottle tightly closed when not in use.
• Avoid freezing the medication.
• Keep it out of the reach of children and pets.

Disposal of ketotifen ophthalmic:

• Follow the specific disposal instructions provided by your healthcare professional or local guidelines.
• Do not dispose of Ketorolac nasal spray in household trash or flush it down the toilet, unless instructed to do so.
• Properly dispose of unused or expired medication to prevent accidental ingestion or misuse.

In case of emergency/overdose

• In case of an emergency or suspected overdose, immediately contact emergency services or go to the nearest emergency room.
• Symptoms of an overdose may include severe drowsiness, confusion, nausea, vomiting, stomach pain, black or bloody stools, or difficulty breathing.

What other information should I know?

• Ketorolac nasal spray is for nasal use only. Do not swallow the medication or apply it to other body parts.
• Inform your healthcare professional about all medications you are taking, including prescription drugs, over-the-counter medications, and supplements, to avoid potential interactions.
• Ketorolac nasal spray is typically prescribed for short-term use. Do not exceed the recommended duration or dosage without consulting your healthcare professional.
• Inform your healthcare professional about any medical conditions you have, such as kidney disease, liver disease, heart problems, high blood pressure, or a history of gastrointestinal disorders.
• Attend regular check-ups with your healthcare professional to monitor your response to Ketorolac nasal spray and assess any potential side effects or complications.

It is important to carefully follow the instructions provided by your healthcare professional and read the medication guide that accompanies Ketorolac nasal spray for specific information regarding storage, disposal, emergency procedures, and other essential details.