WARNING

While ketorolac injection can be effective in relieving pain, it is associated with certain risks and potential side effects. Here are some of the key risks associated with taking ketorolac injection:

• Gastrointestinal effects: Ketorolac can increase the risk of gastrointestinal problems such as stomach ulcers, bleeding, and perforation. These complications can be severe and potentially life-threatening, particularly in older adults or individuals with a history of gastrointestinal issues.
• Kidney effects: Ketorolac can cause or worsen kidney problems, including decreased kidney function, fluid retention, and high blood pressure. This risk is higher in individuals with pre-existing kidney conditions, heart failure, or dehydration.
• Cardiovascular risks: NSAIDs, including ketorolac, may increase the risk of cardiovascular events such as heart attack or stroke, especially when used at high doses or for prolonged periods. This risk may be higher in individuals with existing cardiovascular disease or risk factors.
• Allergic reactions: Some individuals may experience allergic reactions to ketorolac, which can manifest as rash, itching, swelling, dizziness, or difficulty breathing. It’s important to seek immediate medical attention if any signs of an allergic reaction occur.
• Other side effects: Common side effects of ketorolac injection may include nausea, indigestion, headache, dizziness, drowsiness, and injection site reactions. These side effects are generally temporary and go away on their own.

It is crucial to use ketorolac injection as prescribed by a healthcare professional and for the shortest duration necessary. It should not be used in conjunction with other NSAIDs, and alcohol consumption should be avoided while taking ketorolac due to increased risk of gastrointestinal bleeding. If you have any concerns or experience any unusual side effects, it’s important to consult with your healthcare provider for guidance.

Why is this medication prescribed?

Ketorolac injection is a medication that belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily prescribed for the short-term relief of moderate to severe pain, such as postoperative pain or pain due to kidney stones, injury, or other medical conditions.

How should this medicine be used?

Ketorolac injection is administered intravenously (into a vein) or intramuscularly (into a muscle) by a healthcare professional. The dosage and duration of treatment will depend on the specific condition being treated, the individual’s response to the medication, and other factors determined by the healthcare provider.

It is important to note that ketorolac injection is typically intended for short-term use only (up to 5 days) due to the potential for serious side effects, including gastrointestinal bleeding and kidney problems. It is not meant for chronic or long-term pain management.

Other uses for this medicine

Ketorolac injection is primarily prescribed for the short-term relief of moderate to severe pain, particularly after surgery or due to conditions like kidney stones or injury. However, it is important to note that the use of ketorolac injection for other purposes beyond its approved indications should be determined by a healthcare professional on an individual basis.

What special precautions should I follow?

When using ketorolac injection, there are several special precautions that need to be considered:

• Allergy or sensitivity: If you have a known allergy to ketorolac or other NSAIDs (such as aspirin or ibuprofen), you should avoid using ketorolac injection, as it may lead to allergic reactions or other severe hypersensitivity reactions.
• History of gastrointestinal problems: If you have a history of gastrointestinal ulcers, bleeding, or perforation, or if you have a stomach or intestinal disorder, it is important to inform your healthcare provider before using ketorolac injection. This medication can increase the risk of gastrointestinal complications.
• Kidney or liver problems: Individuals with impaired kidney or liver function should exercise caution when using ketorolac injection. It can potentially worsen these conditions or lead to further complications.
• Bleeding disorders: Ketorolac injection can affect blood clotting and increase the risk of bleeding. If you have a bleeding disorder or are taking medications that affect blood clotting, it is important to discuss this with your healthcare provider before using ketorolac injection.
• Pregnancy and breastfeeding: Ketorolac is generally not recommended during pregnancy, especially during the third trimester, as it may harm the unborn baby. It is also not recommended while breastfeeding, as the medication can pass into breast milk and potentially harm the nursing infant.
• Interactions with other medications: Ketorolac injection may interact with certain medications, including blood thinners, diuretics, and other NSAIDs. Inform your healthcare provider about all the medications, supplements, or herbal products you are taking to avoid any potential interactions.

It is essential to follow your healthcare provider’s instructions regarding the use of ketorolac injection and to discuss any specific precautions or concerns you may have before starting the medication.

What special dietary instructions should I follow?

Ketorolac injection does not typically require any special dietary instructions. However, it is generally recommended to take it with food or milk to help minimize the risk of stomach upset or gastrointestinal side effects. Following a balanced and healthy diet is always beneficial for overall well-being and can support the healing process if you’re using ketorolac injection to manage pain after surgery or injury.

What should I do if I forget a dose?

Ketorolac injection does not typically require any special dietary instructions. However, it is generally recommended to take it with food or milk to help minimize the risk of stomach upset or gastrointestinal side effects. Following a balanced and healthy diet is always beneficial for overall well-being and can support the healing process if you’re using ketorolac injection to manage pain after surgery or injury.

What side effects can this medication cause?

Ketorolac injection, like any medication, can cause side effects. While not everyone experiences these side effects, some possible side effects associated with ketorolac injection include:

• Gastrointestinal effects: The most common side effects of ketorolac injection are related to the gastrointestinal system. These can include stomach pain, indigestion, nausea, vomiting, diarrhea, and in some cases, gastrointestinal bleeding or ulcers.
• Kidney effects: Ketorolac can affect kidney function, particularly in individuals with pre-existing kidney problems. Side effects may include decreased urine output, swelling or fluid retention, increased blood pressure, and in rare cases, kidney failure.
• Cardiovascular effects: Ketorolac, like other NSAIDs, may increase the risk of cardiovascular events such as heart attack or stroke, especially when used at high doses or for prolonged periods. This risk may be higher in individuals with existing cardiovascular disease or risk factors.
• Allergic reactions: Some individuals may experience allergic reactions to ketorolac injection. Signs of an allergic reaction may include rash, itching, swelling, dizziness, or difficulty breathing. Allergic reactions can be severe and require immediate medical attention.
• Nervous system effects: Ketorolac can cause drowsiness, dizziness, headache, and in rare cases, confusion or hallucinations.
• Injection site reactions: Pain, redness, swelling, or irritation at the site of injection may occur.

It is important to note that this is not an exhaustive list of side effects, and other rare or uncommon side effects may occur. If you experience any concerning or persistent side effects while using ketorolac injection, it is important to inform your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

Storage and disposal of Ketorolac Injection:

• Ketorolac injection should be stored at room temperature, away from excessive heat, moisture, and light.
• It is important to keep it out of the reach of children and pets.
• Do not use ketorolac injection if it has expired or if the solution appears discolored or contains particles.
• Follow the specific storage instructions provided by your healthcare provider or the product labeling.

In case of emergency/overdose

• If you suspect an overdose or experience severe symptoms such as difficulty breathing, chest pain, seizures, or loss of consciousness, call emergency services immediately.
• Contact a poison control center or seek emergency medical attention in your country if available.

What other information should I know?

• Ketorolac injection should be used only as prescribed by your healthcare provider. Do not exceed the recommended dosage or use it for longer than prescribed.
• Inform your healthcare provider about all your current medications, including over-the-counter drugs, supplements, or herbal products, to avoid potential interactions.
• Avoid alcohol consumption while using ketorolac injection, as it can increase the risk of gastrointestinal bleeding.
• Ketorolac injection may affect kidney function and require periodic monitoring of renal function during treatment.
• Inform your healthcare provider if you have a history of asthma, bleeding disorders, heart problems, high blood pressure, or liver or kidney disease.
• Ketorolac injection can interfere with certain laboratory tests. Inform the healthcare provider or laboratory personnel that you are using ketorolac injection before undergoing any tests.
• Attend scheduled follow-up appointments with your healthcare provider to monitor your response to ketorolac injection and address any concerns or side effects.

It is important to consult your healthcare provider or pharmacist for complete and personalized information regarding the storage, disposal, emergency procedures, and any other specific instructions for the use of ketorolac injection.