WARNING

Jatenzo is a medication that contains testosterone undecanoate, which is used to treat adult men with low testosterone levels. While Jatenzo can be effective in managing testosterone deficiency, it also carries certain risks and side effects. Here are some of the potential risks associated with taking Jatenzo:

• Hormonal Imbalances: Jatenzo is a form of testosterone replacement therapy, and it can lead to hormonal imbalances if not used appropriately or if the dosage is too high. This can result in various complications and health issues.
• Cardiovascular Problems: Testosterone therapy, including Jatenzo, has been associated with an increased risk of cardiovascular problems, such as heart attacks, strokes, and blood clots. Individuals with a history of heart disease, high blood pressure, or other cardiovascular conditions may face an elevated risk.
• Liver Issues: Jatenzo can potentially cause liver damage or dysfunction. Regular monitoring of liver function is important while taking this medication.
• Mood Changes: Some individuals may experience mood swings, irritability, or even depression while using Jatenzo. Monitoring for emotional and psychological changes is crucial.
• Sleep Apnea: Jatenzo can worsen or contribute to sleep apnea, a sleep disorder characterized by breathing disruptions during sleep. Individuals with sleep apnea or other breathing problems should exercise caution while using this medication.
• Prostate Problems: Testosterone replacement therapy, including Jatenzo, may stimulate the growth of existing prostate tumors or potentially increase the risk of developing prostate cancer. Regular prostate examinations are important for individuals on this medication.
• Infertility: Taking Jatenzo can suppress the production of natural testosterone and sperm production, leading to infertility. This is particularly important for individuals who wish to maintain or regain fertility.

It’s important to note that the risks and side effects of Jatenzo can vary depending on individual circumstances, medical history, and dosage. It is crucial to consult with a healthcare professional who can assess your specific situation and provide appropriate guidance.

Why is this medication prescribed?

Jatenzo is prescribed to treat low testosterone levels in adult males, a condition known as hypogonadism. Testosterone is an essential hormone in males that plays a crucial role in the development and maintenance of male sexual characteristics, muscle mass, bone density, and overall well-being.

Low testosterone levels can occur due to various reasons, including primary testicular failure, hypothalamic-pituitary disorders, or certain medical conditions. When testosterone levels are insufficient, it can lead to symptoms such as fatigue, decreased sex drive, erectile dysfunction, decreased muscle mass, and mood changes.

Jatenzo contains testosterone undecanoate, which is an androgen hormone. By supplementing the body with exogenous testosterone, Jatenzo helps raise testosterone levels back to normal range, thereby alleviating the symptoms associated with low testosterone.

How should this medicine be used?

Jatenzo is available in oral capsule form and should be taken exactly as prescribed by your healthcare provider. It is important to follow their instructions and the dosing schedule provided on the prescription label. Here are general guidelines for using Jatenzo:

• Take with food: Jatenzo should be taken with food, preferably in the morning and evening meals.
• Swallow whole: Swallow the Jatenzo capsules whole with a full glass of water. Do not chew, crush, or break the capsules.
• Dosage: The dosage of Jatenzo will be determined by your healthcare provider based on your specific needs and testosterone levels. It is important to take the prescribed dosage as instructed. Do not change the dosage or stop taking Jatenzo without consulting your healthcare provider.
• Boxed Warning: Jatenzo carries a Boxed Warning, which is the FDA’s strongest warning. It is important to be aware of the risks associated with Jatenzo, including the potential for serious and potentially life-threatening blood pressure increases. Regular monitoring of blood pressure is crucial during treatment.
• Other instructions: It is important to read and understand the medication guide provided with Jatenzo. If you have any questions or concerns about the usage of Jatenzo, consult your healthcare provider or pharmacist for clarification.

Remember, Jatenzo should only be used under the guidance of a healthcare professional who will consider your specific medical condition and provide personalized instructions for its usage.

Other uses for this medicine

The primary use of Jatenzo is to restore testosterone levels in individuals with low or absent testosterone production. It’s important to note that Jatenzo should only be used as directed by a healthcare professional and should not be used for any other purposes unless specifically prescribed. Off-label use of medications is not recommended without proper medical guidance.

What special precautions should I follow?

Regarding special precautions for Jatenzo, it’s crucial to follow your healthcare provider’s instructions carefully. Here are some general precautions associated with Jatenzo:

• Medical supervision: Jatenzo should only be used under the supervision of a healthcare professional who can monitor your hormone levels and overall health.
• Dosage and timing: Take Jatenzo exactly as prescribed by your doctor. Follow the recommended dosage and dosing schedule.
• Avoid skin contact: Jatenzo is available as an oral capsule. It should be swallowed whole and not crushed, chewed, or opened. Avoid direct skin contact with the medication.
• Blood tests: Regularly monitor your testosterone levels and other relevant blood parameters as advised by your doctor.
• Liver function: Jatenzo can affect liver function, so your doctor may monitor your liver enzymes periodically. Inform your doctor of any existing liver problems.
• Cardiovascular health: Testosterone therapy, including Jatenzo, may have effects on cardiovascular health. Inform your doctor if you have a history of heart disease, high blood pressure, or any other cardiovascular conditions.
• Drug interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as certain medications may interact with Jatenzo.
• Side effects: Be aware of potential side effects, including mood changes, increased aggression, acne, hair loss, headache, nausea, changes in libido, and sleep disturbances. If you experience any concerning side effects, notify your doctor promptly.
• Allergic reactions: If you develop symptoms of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.

Always consult your healthcare provider for personalized guidance and adhere to their recommendations when using Jatenzo or any other medication.

What special dietary instructions should I follow?

When taking Jatenzo, it’s essential to follow specific dietary instructions and guidelines. Here’s what you should keep in mind:

• Take with food: Jatenzo should be taken with a meal that contains fat. This is because testosterone undecanoate is better absorbed when consumed with food, especially food high in fat. Taking it without food may reduce its effectiveness.
• Avoid high-fat meals: While it’s important to take Jatenzo with food, it’s advisable to avoid excessively high-fat meals as they may lead to unwanted weight gain or other health issues. Aim for a balanced diet.
• Take consistently: It’s important to take Jatenzo regularly as prescribed by your healthcare provider. Follow the recommended dosage and schedule to maintain a consistent level of testosterone in your body.

What should I do if I forget a dose?

If you forget to take a dose of Jatenzo, here’s what you should do:

• Take it as soon as you remember: If you realize that you missed a dose and it’s still within a reasonable timeframe (e.g., a few hours), take the missed dose immediately. However, if it’s close to the time for your next scheduled dose, it’s best to skip the missed dose and continue with your regular dosing schedule.
• Do not double dose: Do not take a double dose of Jatenzo to make up for the missed one. Taking more than the prescribed amount can increase the risk of side effects and may not provide additional benefits.
• Consult your healthcare provider: If you frequently forget to take your doses or have concerns about missed doses, it’s advisable to consult your healthcare provider. They can provide you with specific guidance based on your individual circumstances.

What side effects can this medication cause?

Jatenzo (testosterone undecanoate) is a medication prescribed for testosterone replacement therapy in adult males who have low or no testosterone due to certain medical conditions. Like any medication, Jatenzo can potentially cause side effects. Common side effects may include:

• Headache
• Acne
• Increased blood pressure
• Increased hematocrit levels (the proportion of red blood cells in the blood)
• Increased prostate-specific antigen (PSA) levels
• Elevated liver enzymes
• Diarrhea
• Nausea or vomiting
• Increased appetite
• Mood changes, including irritability or aggression

These side effects are usually mild and temporary. However, if you experience any persistent or severe side effects, it’s important to consult your healthcare provider. They can assess your condition and determine the appropriate course of action, such as adjusting the dosage or considering alternative treatments. It’s also worth noting that individual responses to medications can vary, so not everyone will experience the same side effects.

What should I know about storage and disposal of this medication?

1. Storage of Jatenzo:
   • Store Jatenzo at room temperature, between 68°F and 77°F (20°C and 25°C).
   • Keep the medication in its original container, tightly closed, and away from moisture, heat, and light.
   • Do not store it in the bathroom or near the kitchen sink where it could be exposed to moisture.
2. Disposal of Jatenzo:
   • Dispose of Jatenzo according to the guidelines provided by your local regulatory authorities or healthcare provider.
   • Do not dispose of it in household trash or flush it down the toilet unless specifically instructed to do so.

In case of emergency/overdose

• In case of an emergency or overdose, contact your local emergency services or poison control center immediately.
• If possible, have the medication container or label information available to provide relevant details to medical professionals.

What other information should I know?

• Jatenzo should only be used under the supervision of a healthcare professional who will monitor your testosterone levels and adjust the dosage accordingly.
• It is important to follow the prescribed dosage and schedule provided by your healthcare provider.
• Inform your healthcare provider about any other medications, supplements, or medical conditions you have before starting Jatenzo to avoid potential drug interactions or complications.
• Jatenzo may have side effects, and it’s important to report any unusual or severe symptoms to your healthcare provider.
• Regular blood tests may be necessary to monitor your testosterone levels and overall health while taking Jatenzo.
• Jatenzo is not intended for use in women and should be kept out of reach of children.

Remember, the information provided here is a general overview, and it’s important to consult your healthcare provider or pharmacist for specific instructions and guidance regarding the storage, disposal, and emergency procedures related to Jatenzo.