Why is this medication prescribed?

Iressa (generic name: Gefitinib) is a prescription medication primarily used in the treatment of non-small cell lung cancer (NSCLC). It belongs to a class of medications known as tyrosine kinase inhibitors (TKIs). Iressa is specifically indicated for patients with NSCLC that has certain mutations in the epidermal growth factor receptor (EGFR) gene.

EGFR mutations can cause the growth and spread of cancer cells. Iressa works by inhibiting the activity of the EGFR tyrosine kinase enzyme, which helps to slow down or stop the growth of cancer cells. It is important to note that Iressa is only effective in NSCLC patients who have specific EGFR mutations, as determined by a diagnostic test.

How should this medicine be used?

Iressa (Gefitinib) should be used exactly as prescribed by your healthcare provider. It is typically available in tablet form and is taken orally.

Here are some general guidelines for using Iressa, but it’s important to follow the specific instructions provided by your doctor:

• Dosage: Take Iressa exactly as prescribed. The recommended dose may vary depending on factors such as your condition, overall health, and other medications you may be taking. Follow your doctor’s instructions regarding the dosage and duration of treatment.
• Timing: Take Iressa at the same time every day to help maintain a consistent level of the medication in your body.
• Swallowing: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet unless specifically instructed by your doctor or pharmacist.
• Food and beverages: Iressa can be taken with or without food. However, it is generally recommended to take it on an empty stomach, at least one hour before or two hours after a meal.
• Duration of treatment: Continue taking Iressa for as long as your doctor prescribes it. Do not stop taking the medication without consulting your doctor, even if you start to feel better, unless advised otherwise.

It is important to have regular follow-up appointments with your healthcare provider to monitor your progress and discuss any concerns or side effects you may be experiencing while taking Iressa.

Other uses for this medicine

Iressa has been studied and used in the treatment of other types of cancer, such as breast cancer, ovarian cancer, and pancreatic cancer. However, its efficacy in these cancers is still being evaluated, and it is not approved for these indications in many countries.

What special precautions should I follow?

Special precautions for Iressa:

• Allergic reactions: Some individuals may be allergic to Iressa. If you have a known allergy to gefitinib or any of its components, it is important to avoid using this medication.
• Liver and kidney problems: Iressa is metabolized in the liver and eliminated through the kidneys. Individuals with pre-existing liver or kidney problems may require dose adjustments or close monitoring while taking Iressa.
• Interstitial lung disease (ILD): Iressa can cause or worsen ILD, which is a serious lung condition. It is important to inform your healthcare provider if you have a history of lung disease or breathing difficulties.
• Eye disorders: Iressa may cause eye disorders such as corneal erosion or ulceration. If you experience symptoms like eye pain, redness, blurred vision, or increased tears, it is advisable to seek medical attention.
• Pregnancy and breastfeeding: Iressa can harm an unborn baby, so it should not be used during pregnancy. It is also not recommended during breastfeeding, as it may pass into breast milk.

These are just a few special precautions associated with Iressa, and it’s important to consult with a healthcare professional or your doctor for comprehensive information based on your specific medical condition and needs.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Iressa (gefitinib) that need to be followed. However, it’s generally recommended to maintain a healthy and balanced diet while undergoing cancer treatment to support your overall well-being.

What should I do if I forget a dose?

If you forget to take a dose of Iressa, it’s advisable to take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, it’s best to skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one. If you have any concerns or questions about missed doses, it’s always recommended to consult with your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Iressa (generic name: gefitinib) is a medication commonly used for the treatment of non-small cell lung cancer (NSCLC) that has certain genetic mutations. Like any medication, Iressa can have side effects. Some of the common side effects of Iressa include:

• Skin rash: This is the most common side effect of Iressa, usually occurring within the first few weeks of treatment. The rash may be itchy and can range from mild to severe.
• Diarrhea: Iressa can cause an increase in bowel movements, leading to diarrhea. It is important to stay hydrated and inform your doctor if you experience severe or persistent diarrhea.
• Nausea and vomiting: Some people may experience mild to moderate nausea or vomiting while taking Iressa. It is usually manageable with medication.
• Loss of appetite: Iressa can affect your appetite, leading to a decreased desire to eat. It is important to maintain good nutrition during treatment, so inform your doctor if you have a significant loss of appetite.
• Fatigue: Feeling tired or experiencing a lack of energy is a common side effect of Iressa. It is important to get enough rest and avoid activities that require alertness if you feel fatigued.
• Liver problems: Iressa can affect liver function, leading to an increase in liver enzymes. Regular monitoring of liver function is typically performed during treatment.
• Interstitial lung disease (ILD): Although rare, Iressa has been associated with the development of ILD, a lung condition that causes inflammation and scarring. Symptoms may include cough, difficulty breathing, and fever. Prompt medical attention is necessary if you experience any of these symptoms.

It’s important to note that not everyone will experience these side effects, and some individuals may experience additional or different side effects. It’s essential to discuss any concerns or side effects you experience with your doctor or healthcare provider, as they can provide guidance and support.

What should I know about storage and disposal of this medication?

Storage and disposal of Iressa (gefitinib):

• Storage: Store Iressa at room temperature, away from excessive heat, moisture, and light. Follow the specific storage instructions provided by your pharmacist or included in the medication packaging.
• Disposal: It’s important to dispose of unused or expired medication properly to prevent accidental ingestion or environmental contamination. Follow your local regulations and guidelines for medication disposal. You can consult with your pharmacist or local waste management authority for information on how to safely dispose of Iressa.

In case of emergency/overdose

If you believe you have taken an overdose of Iressa or are experiencing severe side effects, it is important to seek immediate medical attention. Contact your local emergency services or go to the nearest emergency room. Be sure to bring the medication packaging or any remaining tablets with you to assist healthcare providers in assessing the situation.

What other information should I know?

• Regular check-ups: Your healthcare provider will monitor your progress and may conduct regular check-ups, including blood tests, to assess the effectiveness of Iressa and monitor for any potential side effects.
• Drug interactions: Inform your doctor about all the medications, supplements, and herbal products you are taking, as Iressa may interact with certain medications and affect their effectiveness or increase the risk of side effects.
• Driving and operating machinery: Iressa may cause side effects such as dizziness or blurred vision. It’s important to assess how the medication affects you before driving or operating machinery. If you experience these side effects, it’s best to avoid activities that require alertness and clear vision until you feel safe to engage in them.
• Compliance with treatment: It’s important to take Iressa exactly as prescribed by your healthcare provider. Do not alter the dosage or stop the medication without consulting your doctor, as this may affect the effectiveness of the treatment.
• Support and resources: Living with cancer and undergoing treatment can be challenging. Reach out to your healthcare team for support, and consider connecting with support groups or organizations that provide assistance to cancer patients and their families.

Remember, the information provided here is a general overview, and it’s always recommended to consult with your healthcare provider or pharmacist for specific instructions, guidance, and any additional information related to your individual circumstances and treatment plan.