Why is this medication prescribed?

Horizant is a prescription medication that contains the active ingredient gabapentin enacarbil. It is primarily prescribed for the treatment of two conditions:

• Restless Legs Syndrome (RLS): Horizant is approved by the U.S. Food and Drug Administration (FDA) for the management of moderate-to-severe primary RLS. RLS is a neurological disorder characterized by an irresistible urge to move the legs, often accompanied by uncomfortable sensations. Horizant helps alleviate these symptoms and improve sleep quality in individuals with RLS.
• Postherpetic Neuralgia (PHN): Horizant is also approved for the treatment of PHN, which is a persistent nerve pain that arises after an outbreak of shingles. Shingles is a viral infection caused by the varicella-zoster virus. PHN can cause long-lasting pain and discomfort even after the rash has healed, and Horizant can help relieve the nerve pain associated with this condition.

How should this medicine be used?

As for how to use Horizant, it is available in extended-release tablets, and the dosage and administration instructions should be followed as directed by your healthcare provider. Here are some general guidelines:

• Timing: Horizant is usually taken once daily, preferably in the evening with food. Taking it with food can help improve absorption and reduce the risk of side effects.
• Swallowing: The tablets should be swallowed whole and not chewed, crushed, or split. Breaking the tablets may affect the way they are released in the body.
• Dosage: The dosage of Horizant will depend on the condition being treated and individual factors. Your healthcare provider will determine the appropriate dosage for you based on your specific needs.
• Titration: In some cases, the dosage may need to be gradually increased over time to minimize potential side effects. This process is known as titration and should be done under the guidance of your healthcare provider.
• Follow-up: It is important to attend regular follow-up appointments with your healthcare provider while taking Horizant to monitor its effectiveness and make any necessary adjustments to your treatment plan.

It’s crucial to note that these instructions are general guidelines, and individual circumstances may vary. Always consult your healthcare provider or refer to the prescribing information provided with the medication for specific dosing and usage instructions.

Other uses for this medicine

Horizant is a medication that contains the active ingredient gabapentin enacarbil. It is primarily used to treat restless legs syndrome (RLS) and postherpetic neuralgia (PHN), a type of nerve pain that occurs after a herpes zoster infection (shingles). However, gabapentin, the active component of Horizant, is also used for other medical conditions. Here are some other uses for gabapentin:

• Epilepsy: Gabapentin is commonly prescribed as an anticonvulsant medication for the treatment of epilepsy. It helps to control seizures and prevent their occurrence.
• Neuropathic pain: In addition to PHN, gabapentin is used to manage other types of neuropathic pain, including diabetic neuropathy (nerve pain associated with diabetes) and peripheral neuropathy (nerve damage resulting from conditions like multiple sclerosis or nerve compression).
• Fibromyalgia: Gabapentin may be prescribed to alleviate the pain and discomfort associated with fibromyalgia, a chronic condition characterized by widespread musculoskeletal pain, fatigue, and sleep disturbances.
• Migraine prevention: Some individuals with chronic migraines find gabapentin helpful in reducing the frequency and severity of their migraine attacks.

It’s important to note that the use of gabapentin for these conditions may vary, and the specific dosage and treatment regimen should be determined by a healthcare professional based on individual circumstances.

What special precautions should I follow?

Regarding the special precautions for taking Horizant (gabapentin enacarbil), here are some important considerations:

• Inform your doctor about any known allergies or sensitivities to gabapentin or any other medications.
• Share your complete medical history, including any kidney problems, breathing difficulties, or mood disorders, as gabapentin may require dose adjustments or additional monitoring in these cases.
• Discuss all the medications, supplements, and herbal products you are currently taking, as some substances can interact with gabapentin and affect its effectiveness or increase the risk of side effects.
• Follow the prescribed dosage and schedule provided by your doctor. Do not increase or decrease the dosage without consulting your healthcare provider.
• If you need to discontinue the medication, your doctor will guide you on how to taper the dose gradually to avoid potential withdrawal symptoms.
• It’s important to note that gabapentin may cause drowsiness, dizziness, or impair your ability to concentrate. Avoid activities that require mental alertness or coordination until you know how the medication affects you.
• Avoid consuming alcohol while taking Horizant, as it can enhance the sedative effects of the medication.
• Pregnant or breastfeeding individuals should consult their healthcare provider before taking Horizant or gabapentin due to potential risks to the fetus or infant.

Remember, this information is not exhaustive, and it’s essential to consult a healthcare professional or pharmacist for personalized advice and guidance regarding the use of Horizant or gabapentin.

What special dietary instructions should I follow?

Horizant can be taken with or without food. There are no specific dietary restrictions associated with this medication. However, it’s always a good idea to maintain a healthy and balanced diet.

What should I do if I forget a dose?

• If you forget to take a dose of Horizant, take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Horizant is a brand name for the medication gabapentin enacarbil, which is primarily used to treat restless legs syndrome (RLS) and postherpetic neuralgia (nerve pain that occurs after an outbreak of shingles). Like any medication, Horizant can cause side effects. Common side effects of Horizant include:

• Dizziness: Many individuals experience dizziness or a spinning sensation. It is advisable to avoid driving or operating machinery until you know how the medication affects you.
• Sleepiness or fatigue: Horizant can cause drowsiness or excessive sleepiness, which may impact your ability to concentrate or perform daily activities.
• Headache: Some people may experience headaches while taking Horizant. If the headaches are severe or persistent, it is important to consult a healthcare professional.
• Nausea: Horizant can cause an upset stomach or feelings of nausea. Taking the medication with food may help alleviate this side effect.
• Diarrhea or constipation: Horizant may lead to changes in bowel movements, including diarrhea or constipation.
• Increased appetite or weight gain: Some individuals may experience an increase in appetite or weight gain while taking Horizant. It is important to maintain a healthy diet and exercise regularly.
• Peripheral edema: This refers to swelling in the hands, feet, or legs. If you notice any significant swelling, it is recommended to inform your doctor.
• Abnormal coordination: Horizant may affect coordination and balance, leading to difficulties with tasks that require precise movements.
• Mood changes: In some cases, Horizant can cause mood swings or changes in emotions. If you experience any significant changes in mood, it is important to discuss them with your healthcare provider.
• Respiratory infections: Some individuals taking Horizant may experience an increased risk of respiratory infections, such as the common cold or flu.

It’s important to note that this list may not be exhaustive, and individual reactions to medications can vary. If you are prescribed Horizant and experience any concerning or persistent side effects, it is recommended to consult your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

1. Storage:
   • Keep Horizant in its original container with the lid tightly closed.
   • Store it at room temperature, away from excessive heat, moisture, and light.
   • Keep it out of reach and sight of children and pets.
2. Disposal:
   • Dispose of unused or expired Horizant properly.
   • Follow your local regulations or guidelines for medication disposal.
   • If you’re unsure about the proper disposal method, consult your pharmacist or healthcare provider.

In case of emergency/overdose

• In case of a medical emergency, call your local emergency number immediately (e.g., 911 in the United States).
• Inform the medical professionals about the medication involved (Horizant) and the situation.
• An overdose of Horizant can have serious consequences and may require immediate medical attention.
• Symptoms of an overdose may include extreme drowsiness, blurred vision, slurred speech, and difficulty breathing.
• If you suspect an overdose or someone has taken more Horizant than prescribed, contact emergency services or a poison control center right away.

What other information should I know?

• Take Horizant exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage or alter the dosing schedule without medical advice.
• Inform your doctor about any other medications, supplements, or medical conditions you have before starting Horizant to avoid potential interactions or complications.
• Horizant may cause dizziness or drowsiness. Avoid driving, operating machinery, or engaging in activities that require mental alertness until you know how the medication affects you.
• Inform your healthcare provider if you experience any unusual or severe side effects while taking Horizant.

It’s important to note that this information is a general overview, and you should always consult your healthcare provider or pharmacist for specific instructions and guidance regarding the storage, disposal, emergencies, and overdose of Horizant.