WARNING

Hexalen is an anti-cancer medication that contains the active ingredient altretamine. While Hexalen can be effective in treating certain types of cancer, it also carries certain risks and potential side effects. Here are some important considerations:

• Bone marrow suppression: Hexalen can affect the bone marrow’s ability to produce new blood cells, leading to a decreased number of white blood cells, red blood cells, and platelets. This can increase the risk of infections, anemia, and bleeding.
• Gastrointestinal issues: Hexalen commonly causes gastrointestinal side effects, including nausea, vomiting, diarrhea, and loss of appetite. These symptoms can be severe in some cases and may require supportive medications or adjustments in dosage.
• Neurotoxicity: Hexalen can sometimes cause neurological side effects such as dizziness, confusion, disorientation, and peripheral neuropathy. It is important to report any such symptoms to your healthcare provider.
• Liver toxicity: There have been rare reports of liver toxicity associated with Hexalen use. Regular liver function tests may be necessary to monitor for any potential liver problems.
• Allergic reactions: Some individuals may experience allergic reactions to Hexalen, including rash, itching, swelling, and difficulty breathing. If any signs of an allergic reaction occur, immediate medical attention should be sought.
• Interactions with other medications: Hexalen may interact with certain medications, including blood thinners and drugs that affect liver enzymes. Inform your healthcare provider about all the medications you are taking to prevent any potential interactions.

It is crucial to note that the above list is not exhaustive, and other side effects or risks may exist. Hexalen should only be used under the supervision of a qualified healthcare professional who can monitor its effects and manage any adverse reactions. Always consult with your doctor to assess the potential risks and benefits of Hexalen based on your individual circumstances.

Why is this medication prescribed?

Hexalen is a prescription medication that contains the active ingredient altretamine. It is primarily used in the treatment of ovarian cancer that has recurred (come back) after previous treatment with other chemotherapy drugs.

Hexalen is classified as an antineoplastic agent, specifically an alkylating agent. It works by interfering with the growth of cancer cells, preventing them from multiplying and spreading further.

How should this medicine be used?

The dosage and administration of Hexalen may vary depending on various factors such as the patient’s overall health, the stage and type of cancer being treated, and other medications they may be taking. It is essential to follow the specific instructions provided by the prescribing doctor or included in the medication’s package insert.

Typically, Hexalen is taken orally in the form of capsules. The capsules are usually taken four times a day on an empty stomach, at least one hour before or two hours after a meal. It is important to swallow the capsules whole and not chew or open them. The treatment duration and dosage schedule will be determined by the healthcare professional based on individual circumstances.

It is crucial to adhere to the prescribed dosage and follow the recommended schedule strictly. If there are any concerns or questions about the appropriate use of Hexalen, it is advisable to consult a healthcare professional or the prescribing doctor for clarification.

Other uses for this medicine

Hexalen (altretamine) is primarily used for the treatment of recurrent ovarian cancer. However, it may also be prescribed for other types of cancer, such as breast cancer and non-small cell lung cancer, when other treatment options have not been effective.

What special precautions should I follow?

When using Hexalen, it is important to take certain precautions to ensure safe and effective treatment. Here are some key precautions to keep in mind:

• Pregnancy and breastfeeding: Hexalen can cause harm to a developing fetus, so it should not be used during pregnancy. It is important to use effective contraception during treatment and for at least six months after the last dose. Hexalen may also pass into breast milk, so breastfeeding should be avoided while taking the medication.
• Allergies: Inform your doctor about any known allergies to altretamine or any other medications. Hexalen may contain inactive ingredients that could cause allergic reactions or other problems.
• Blood cell counts: Hexalen can affect the production of blood cells in the bone marrow. Regular blood tests will be conducted to monitor your blood cell counts, including white blood cells, red blood cells, and platelets. In some cases, treatment may need to be adjusted or temporarily stopped if blood counts drop too low.
• Kidney and liver function: Hexalen is metabolized in the liver and excreted through the kidneys. Your doctor may perform regular tests to monitor your kidney and liver function during treatment.
• Neurotoxicity: Hexalen may cause nerve damage, leading to symptoms such as numbness, tingling, or weakness in the hands or feet. Inform your doctor if you experience any neurological symptoms during treatment.
• Interactions with other medications: It is important to inform your doctor about all medications, including prescription, over-the-counter, and herbal supplements, that you are taking. Some medications may interact with Hexalen and affect its effectiveness or increase the risk of side effects.
• Driving and operating machinery: Hexalen may cause dizziness, confusion, or drowsiness. If you experience these side effects, avoid driving or operating machinery until you know how the medication affects you.

These are general precautions associated with the use of Hexalen. It is important to consult with your healthcare provider for specific instructions and advice based on your individual circumstances.

What special dietary instructions should I follow?

If you are prescribed a medication or supplement with the name Hexalenn, consulting with your healthcare provider or pharmacist. They will be able to provide you with detailed instructions on how to take the medication, including any specific dietary considerations or potential interactions with food or other substances.

What should I do if I forget a dose?

Regarding missed doses, it is generally advised to follow the instructions provided by your healthcare professional or the medication’s packaging. However, if you forget to take a dose of any medication, it’s best to contact your healthcare provider or pharmacist for guidance. They can provide you with specific instructions based on the medication, its dosage, and the timing of the missed dose.

What side effects can this medication cause?

Altretamine, or Hexalen, may cause various side effects. These can vary from person to person and can range from mild to severe. Some common side effects of Hexalen may include:

• Nausea and vomiting
• Loss of appetite
• Diarrhea or constipation
• Fatigue or weakness
• Dizziness
• Headache
• Peripheral neuropathy (numbness, tingling, or pain in the hands or feet)
• Changes in taste or metallic taste in the mouth
• Bone marrow suppression (reduced production of blood cells)
• Elevated liver enzymes
• Allergic reactions (rare but possible)

It’s important to note that this is not an exhaustive list, and other side effects may occur. Additionally, individual responses to medications can vary, and some people may experience different or more severe side effects. It’s crucial to report any concerning or persistent side effects to your healthcare provider for further evaluation.

What should I know about storage and disposal of this medication?

When it comes to storage and disposal of Hexalen (altretamine), it’s important to follow the specific instructions provided by your healthcare provider or the medication’s packaging. However, here are some general guidelines:

• Storage: Store Hexalen at room temperature, away from moisture, heat, and light. Follow any specific storage instructions provided with the medication.
• Disposal: Properly dispose of unused or expired Hexalen according to local regulations and guidelines. Do not flush it down the toilet or pour it into drains unless specifically instructed to do so. Instead, consult with your healthcare provider, pharmacist, or local waste disposal authorities on the recommended disposal method.

In case of emergency/overdose

In case of an emergency or overdose involving Hexalen, it’s crucial to seek immediate medical attention. Contact your local emergency services or call your local poison control center for guidance. Be prepared to provide information about the medication, the dosage taken, and the time of ingestion.

What other information should I know?

Here are a few additional points to keep in mind:

• Pregnancy and breastfeeding: Discuss with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Hexalen may cause harm to an unborn baby, and it is not recommended during breastfeeding.
• Interactions: Inform your healthcare provider about all the medications, supplements, and herbal products you are taking. Certain medications or substances may interact with Hexalen, potentially affecting its effectiveness or increasing the risk of side effects.
• Regular check-ups: Attend all scheduled medical appointments and laboratory tests as recommended by your healthcare provider. They will monitor your response to Hexalen and check for any potential complications or side effects.
• Driving and operating machinery: Hexalen may cause dizziness or fatigue. It’s important to assess how the medication affects you before driving, operating heavy machinery, or engaging in activities that require alertness.
• Inform healthcare professionals: Make sure to inform all healthcare professionals involved in your care (including dentists and specialists) that you are taking Hexalen. This helps them have a complete understanding of your medication regimen and make appropriate treatment decisions.

Remember, the information provided here is a general overview, and it’s important to consult your healthcare provider or pharmacist for specific instructions and guidance related to Hexalen based on your individual circumstances.