WARNING

According to studies, older adults who use antipsychotics, such as haloperidol, a medication for mental illness, have a higher risk of dying while undergoing treatment. Dementia is a brain disorder that affects an individual’s memory, ability to think clearly, communicate, and perform daily tasks.

The FDA has not approved haloperidol injection or haloperidol extended-release injection for the management of behavioral issues in dementia-affected older individuals. If you, a member of your family, or a person you are caring for has dementia and is taking haloperidol injection or haloperidol extended-release injection, speak with the doctor who recommended this drug.

A haloperidol injection or a haloperidol extended-release injection may carry some risks. Discuss these risks with your doctor.

Why is this medication prescribed?

Haloperidol Injection is prescribed for several reasons, primarily for the treatment of certain mental and mood disorders. Here are some specific indications for which Haloperidol Injection may be prescribed:

• Schizophrenia: Haloperidol Injection is commonly used in the management of schizophrenia, a chronic psychiatric disorder characterized by distorted thinking, delusions, hallucinations, and disorganized behavior. It helps to reduce the symptoms of psychosis and restore a person’s ability to function.
• Acute Psychotic Episodes: Haloperidol Injection may be prescribed during acute episodes of psychosis, such as when an individual experiences severe agitation, aggression, or extreme disorientation. The injection allows for rapid symptom control and sedation.
• Severe Behavioral Disorders: In certain cases, Haloperidol Injection may be used to manage severe behavioral problems associated with conditions like Tourette’s syndrome or other disruptive behavior disorders. It can help reduce impulsivity, aggression, and self-injurious behaviors.
• Delirium: Haloperidol Injection may be used to treat delirium, a state of acute confusion and cognitive impairment that can occur due to various factors, such as drug intoxication, withdrawal, or underlying medical conditions.
• Nausea and Vomiting: Haloperidol Injection can be used as an antiemetic (anti-nausea) medication to manage severe nausea and vomiting that may occur due to chemotherapy, radiation therapy, or other medical conditions.

How should this medicine be used?

Haloperidol Injection should be used as directed by a healthcare professional, and it is typically administered in a healthcare setting, such as a hospital or clinic, by a trained healthcare provider. Here are some general guidelines on the use of Haloperidol Injection:

• Administration: Haloperidol Injection is given by deep intramuscular injection or slow intravenous injection. The route of administration will depend on the specific situation and the healthcare professional’s judgment.
• Dosage: The dosage of Haloperidol Injection will vary depending on the individual’s condition, severity of symptoms, and response to the medication. The healthcare professional will determine the appropriate dosage for each patient. It is important to follow the prescribed dosage and not alter it without medical supervision.
• Frequency: The frequency of Haloperidol Injection will also be determined by the healthcare professional. In some cases, a single injection may be sufficient, while in others, multiple doses may be required. Follow the prescribed schedule and do not deviate from it without medical advice.
• Duration: The duration of treatment with Haloperidol Injection will depend on the individual’s condition and the healthcare professional’s assessment. It may be used for short-term symptom control during acute episodes or for longer-term maintenance therapy in chronic conditions like schizophrenia. Follow the recommended duration of treatment as advised by the healthcare professional.

Other uses for this medicine

Haloperidol Injection may have off-label uses, meaning it may be prescribed for conditions not officially approved by regulatory authorities. However, it’s important to note that off-label use should only be done under the guidance of a healthcare professional. Some off-label uses of Haloperidol Injection may include:

• Agitation in the Elderly: Haloperidol Injection may be used to manage severe agitation in elderly individuals who have dementia or other related conditions.
• Delirium in the Intensive Care Unit (ICU): Haloperidol Injection can be used to treat delirium in critically ill patients admitted to the ICU.
• Severe Nausea and Vomiting: In some cases, Haloperidol Injection may be used as an antiemetic (anti-nausea) medication for severe nausea and vomiting not related to chemotherapy or radiation therapy.

What special precautions should I follow?

Now, regarding the special precautions for Haloperidol Injection, it’s important to be aware of the following:

• Allergies: Inform your healthcare provider if you are allergic to haloperidol or any other medications. This is crucial to avoid any potential allergic reactions.
• Medical History: Provide a comprehensive medical history to your healthcare provider, including any previous or current medical conditions, especially if you have a history of heart problems, liver disease, kidney disease, epilepsy, Parkinson’s disease, or any movement disorders.
• Medications: Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Certain medications, such as other antipsychotics, tranquilizers, antidepressants, and certain antibiotics, can interact with Haloperidol Injection and lead to adverse effects.
• Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The use of Haloperidol Injection during pregnancy or breastfeeding should be carefully considered, as it may have potential risks to the developing fetus or infant.
• Motor and Cognitive Impairment: Haloperidol Injection may cause drowsiness, dizziness, or blurred vision. It may impair motor coordination and cognitive function. Avoid activities that require alertness and coordination, such as driving or operating machinery, until you know how the medication affects you.
• Side Effects: Be aware of the potential side effects of Haloperidol Injection, which may include extrapyramidal symptoms (movement disorders), sedation, dizziness, dry mouth, constipation, and changes in blood pressure. Report any persistent or severe side effects to your healthcare provider.

What special dietary instructions should I follow?

There are no specific dietary restrictions or instructions associated with Haloperidol Injection. However, it is generally recommended to follow a balanced and healthy diet while taking any medication.

What should I do if I forget a dose?

Regarding a missed dose of Haloperidol Injection, it is important to consult with your healthcare provider or pharmacist for specific instructions based on your situation. The actions to take may vary depending on factors such as the reason for taking the medication, the dosage schedule, and the time elapsed since the missed dose.

What side effects can this medication cause?

Haloperidol is an antipsychotic medication commonly used to treat conditions such as schizophrenia, acute psychosis, and severe behavioral disturbances. Haloperidol injections, like any medication, can cause side effects. Some common side effects of Haloperidol Injection include:

• Extrapyramidal symptoms (EPS): These are movement disorders that can include muscle stiffness, tremors, restlessness, and abnormal movements such as dystonia (involuntary muscle contractions) and akathisia (a feeling of inner restlessness). These symptoms can be distressing but can often be managed with additional medications.
• Sedation: Haloperidol can cause drowsiness and sedation, which may impair cognitive function and motor skills. It is important to avoid driving or operating machinery until you know how the medication affects you.
• Hypotension: Haloperidol can lower blood pressure, leading to dizziness or lightheadedness, especially when standing up quickly. It is important to rise slowly from a sitting or lying position to minimize the risk of falls.
• Anticholinergic effects: Haloperidol can have anticholinergic effects, resulting in dry mouth, blurred vision, constipation, urinary retention, and difficulty urinating.
• Metabolic effects: Like many antipsychotic medications, Haloperidol can lead to metabolic changes such as weight gain, increased blood sugar levels, and increased cholesterol and triglyceride levels. Regular monitoring of these parameters may be necessary.
• Neuroleptic malignant syndrome (NMS): Although rare, Haloperidol can cause a potentially life-threatening condition called neuroleptic malignant syndrome. Symptoms include high fever, muscle rigidity, altered mental status, irregular heartbeat, and autonomic dysfunction. Immediate medical attention is required if these symptoms occur.
• Cardiac effects: Haloperidol may rarely cause irregular heart rhythms, particularly in individuals with existing cardiac conditions. It is important to notify your healthcare provider if you experience palpitations, chest pain, or other cardiac symptoms.

These are not all possible side effects of Haloperidol Injection. Other side effects may occur, and individual responses to the medication can vary. It is important to discuss any concerns or unusual symptoms with your healthcare provider.

What should I know about storage and disposal of this medication?

Storage and disposal of Haloperidol Injection:

• Storage: Haloperidol Injection should be stored at room temperature, away from light and moisture. Follow the specific storage instructions provided by your healthcare provider or the manufacturer.
• Disposal: It is important to dispose of Haloperidol Injection properly and safely. Do not dispose of it in household trash or flush it down the toilet unless instructed to do so. Contact your local pharmacy or healthcare facility for guidance on how to properly dispose of unused medications.

In case of emergency/overdose

In case of emergency or overdose:

• If you or someone else is experiencing an emergency situation or overdose, immediately call emergency services or go to the nearest emergency room.
• Overdose symptoms may include extreme drowsiness, confusion, restlessness, muscle stiffness, tremors, irregular heartbeat, fainting, and seizures.
• Provide healthcare professionals with as much information as possible, including the amount of medication taken, the time of ingestion, and any other relevant details.

What other information should I know?

• Inform your healthcare provider about any known allergies or sensitivities to Haloperidol or other medications.
• Mention any other medications, supplements, or herbal products you are taking to avoid potential drug interactions.
• Haloperidol may impair your ability to drive or operate machinery due to sedation and other side effects. Exercise caution and avoid such activities until you know how the medication affects you.
• Attend regular follow-up appointments with your healthcare provider to monitor the effectiveness of the medication and address any concerns or side effects.
• It is important to take Haloperidol as prescribed and not stop or adjust the dosage without consulting your healthcare provider.
• Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as Haloperidol may have potential risks and considerations in these situations.

Remember, the information provided here is general in nature. It’s important to consult your healthcare provider or pharmacist for specific guidelines and advice regarding the use of Haloperidol based on your individual circumstances.