Why is this medication prescribed?

Fulyzaq (generic name: crofelemer) is prescribed to treat diarrhea in HIV/AIDS patients who are on antiretroviral therapy. This medication works by normalizing the balance of fluid and electrolytes in the gut, helping to reduce the frequency and severity of diarrhea episodes.

How should this medicine be used?

Here’s how Fulyzaq is typically used:

• Dosage: The usual dose is one 125 mg delayed-release tablet taken orally twice daily.
• Administration: Fulyzaq should be taken with food, ideally during or immediately after a meal.
• Duration: Treatment duration may vary depending on the individual’s response to the medication and the severity of their condition. It’s important to follow the healthcare provider’s instructions regarding the duration of treatment.
• Compliance: It’s essential to take Fulyzaq exactly as prescribed by the healthcare provider. Missing doses or stopping treatment prematurely may reduce its effectiveness.
• Monitoring: Patients should be monitored regularly by their healthcare provider to assess the response to treatment and to manage any potential side effects.

It’s important to note that Fulyzaq is specifically indicated for HIV/AIDS patients with diarrhea, and it may not be suitable for other types of diarrhea or for individuals who do not have HIV/AIDS. As always, individuals should consult with their healthcare provider for personalized medical advice and treatment recommendations.

Other uses for this medicine

Fulyzaq (crofelemer) is primarily indicated for the treatment of diarrhea in HIV/AIDS patients on antiretroviral therapy. However, there have been studies exploring its potential for other conditions such as acute infectious diarrhea and diarrhea-predominant irritable bowel syndrome (IBS-D). While further research is needed to establish its efficacy for these conditions, Fulyzaq is not currently approved for use beyond its HIV/AIDS indication.

What special precautions should I follow?

Regarding special precautions for Fulyzaq, here are some key points to consider:

• Allergies: Individuals with known allergies or hypersensitivity to crofelemer or any of the components in Fulyzaq should avoid its use.
• Drug Interactions: It’s important to inform your healthcare provider about all medications, supplements, and herbal products you are taking, as Fulyzaq may interact with certain medications.
• Pregnancy and Breastfeeding: The safety of Fulyzaq during pregnancy and breastfeeding has not been established. Consult with your healthcare provider before using Fulyzaq if you are pregnant, planning to become pregnant, or breastfeeding.
• Liver and Kidney Function: Fulyzaq is primarily excreted through the feces, and its clearance may be affected in individuals with impaired liver or kidney function. Dose adjustments may be necessary in such cases.
• Gastrointestinal Disorders: Individuals with severe gastrointestinal disorders or conditions that may predispose them to complications from changes in fluid and electrolyte balance should use Fulyzaq with caution.
• Side Effects: Common side effects of Fulyzaq may include upper respiratory tract infection, bronchitis, cough, flatulence, and increased bilirubin levels. If you experience any adverse reactions while taking Fulyzaq, notify your healthcare provider.
• Compliance: It’s essential to take Fulyzaq exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage or stop taking the medication without consulting your healthcare provider.

As with any medication, it’s crucial to follow your healthcare provider’s instructions and guidance when using Fulyzaq. They can provide personalized advice based on your medical history and individual circumstances.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with taking Fulyzaq. However, it’s generally recommended to take the medication with food, ideally during or immediately after a meal. This can help improve its absorption and effectiveness.

What should I do if I forget a dose?

If you forget to take a dose of Fulyzaq, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. If you are unsure about what to do, consult your healthcare provider or pharmacist for guidance. It’s important to maintain a consistent dosing schedule to ensure the effectiveness of the medication.

What side effects can this medication cause?

Fulyzaq (crofelemer) may cause side effects in some individuals. Common side effects reported with the use of Fulyzaq include:

• Upper respiratory tract infection
• Bronchitis
• Cough
• Flatulence (gas)
• Increased bilirubin levels

These side effects are typically mild to moderate in severity and may resolve on their own without requiring medical intervention. However, if any of these side effects persist or worsen, or if you experience any other unusual symptoms while taking Fulyzaq, it’s important to notify your healthcare provider.

In rare cases, Fulyzaq may cause more serious side effects or allergic reactions. Seek immediate medical attention if you experience any of the following symptoms after taking Fulyzaq:

• Severe or persistent diarrhea
• Severe abdominal pain or cramping
• Bloody or black stools
• Signs of an allergic reaction, such as rash, itching, swelling of the face, tongue, or throat, severe dizziness, or difficulty breathing

It’s essential to report any side effects or adverse reactions to your healthcare provider, as they can provide guidance and make any necessary adjustments to your treatment plan. Additionally, if you have any concerns about the side effects of Fulyzaq, discuss them with your healthcare provider before starting the medication.

What should I know about storage and disposal of this medication?

Storage and disposal of Fulyzaq:

• Storage: Store Fulyzaq at room temperature between 20-25°C (68-77°F). Keep the medication in its original container, tightly closed, and away from moisture, heat, and light. Avoid storing Fulyzaq in the bathroom or near the kitchen sink where it could be exposed to moisture.
• Disposal: Dispose of any unused or expired Fulyzaq tablets according to local regulations and guidelines. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Consult with your pharmacist or healthcare provider on the proper disposal method for Fulyzaq.

In case of emergency/overdose

If you suspect an overdose of Fulyzaq or experience severe symptoms such as severe diarrhea, abdominal pain, or difficulty breathing, seek immediate medical attention or contact your local poison control center. Be sure to provide information about the medication taken, including the name (crofelemer or Fulyzaq), dosage, and time of ingestion.

What other information should I know?

• Keep all appointments with your healthcare provider for regular check-ups and monitoring while taking Fulyzaq.
• Do not share Fulyzaq with others, even if they have similar symptoms, as it may not be appropriate for their condition.
• Follow your healthcare provider’s instructions carefully, including dosage and frequency of administration, to ensure the effectiveness of Fulyzaq and minimize the risk of side effects.
• Inform your healthcare provider about any other medical conditions you have, especially liver or kidney problems, as well as any other medications, supplements, or herbal products you are taking, to avoid potential drug interactions.
• If you have any questions or concerns about Fulyzaq or its use, consult with your healthcare provider or pharmacist for further information and guidance.