Why is this medication prescribed?

Finerenone is a medication primarily prescribed for the treatment of chronic kidney disease (CKD) in patients with type 2 diabetes. It belongs to a class of drugs known as mineralocorticoid receptor antagonists (MRAs). Finerenone works by blocking the effects of aldosterone, a hormone that can contribute to kidney damage and cardiovascular complications in people with CKD and diabetes.

How should this medicine be used?

Here’s how Finerenone is typically used:

• Dosage: The dosage of Finerenone can vary depending on the individual’s condition and medical history. It is usually taken orally once daily.
• Administration: Finerenone tablets are taken with water, with or without food. It’s essential to follow the dosage instructions provided by the healthcare provider or pharmacist.
• Compliance: It’s crucial to take Finerenone regularly and at the same time each day to maintain consistent levels of the medication in the body.
• Monitoring: Patients prescribed Finerenone may require regular monitoring of their kidney function, blood pressure, and electrolyte levels to ensure the medication is working effectively and to detect any potential side effects.
• Adverse Effects: Like any medication, Finerenone may cause side effects, including hyperkalemia (high potassium levels), dizziness, fatigue, and changes in kidney function. It’s essential to report any adverse effects to the healthcare provider promptly.
• Interactions: Finerenone may interact with other medications, including potassium supplements, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain blood pressure medications. It’s crucial to inform the healthcare provider about all medications and supplements being taken to avoid potential interactions.
• Duration: The duration of Finerenone treatment varies depending on the individual’s response to the medication and their underlying medical condition. It’s essential to continue taking Finerenone as prescribed unless otherwise directed by the healthcare provider.

As always, it’s essential to consult a healthcare professional for personalized medical advice and guidance regarding the use of Finerenone or any other medication.

Other uses for this medicine

Apart from its primary indications for CKD, CV risk reduction, and HFrEF, research may explore other potential uses of finerenone. However, it’s essential to note that using medications for off-label purposes should only be done under the guidance of a qualified healthcare professional.

What special precautions should I follow?

As for special precautions to follow when using Finerenone:

• Kidney function monitoring: Since Finerenone primarily affects kidney function, it’s important to monitor kidney function regularly, especially at the initiation of treatment and periodically thereafter.
• Potassium monitoring: Finerenone can cause hyperkalemia (high potassium levels), so potassium levels should be monitored regularly, particularly in patients at risk of hyperkalemia, such as those with impaired kidney function or those taking other medications that can increase potassium levels.
• Drug interactions: Finerenone may interact with other medications, particularly those that affect potassium levels or blood pressure. Inform your healthcare provider about all medications, supplements, and herbal products you are taking before starting Finerenone.
• Special populations: Special caution is warranted when using Finerenone in certain populations, such as pregnant or breastfeeding women, pediatric patients, and individuals with severe liver impairment. Use in these populations should be carefully considered and monitored by a healthcare professional.
• Adverse effects: Be aware of potential side effects of Finerenone, including dizziness, fatigue, hypotension (low blood pressure), and changes in kidney function. Report any adverse effects to your healthcare provider promptly.

Always follow your healthcare provider’s instructions and guidance when using Finerenone or any other medication. They can provide personalized advice based on your medical history and specific needs.

What special dietary instructions should I follow?

Special dietary instructions for Finerenone:

• Potassium-rich foods: Since Finerenone can increase potassium levels in the blood, it may be necessary to limit intake of potassium-rich foods, such as bananas, oranges, tomatoes, potatoes, and spinach. Your healthcare provider can provide specific dietary recommendations based on your individual needs and potassium levels.
• Salt intake: Finerenone may be used to treat conditions such as hypertension, where reducing salt intake can be beneficial. Follow any dietary recommendations provided by your healthcare provider to manage your salt intake appropriately.

What should I do if I forget a dose?

If you miss a dose of Finerenone, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose. If you are unsure about what to do, consult your healthcare provider or pharmacist for guidance. It’s important to maintain a consistent dosing schedule to ensure the effectiveness of the medication.

What side effects can this medication cause?

Finerenone, like any medication, can cause side effects, although not everyone will experience them. Some common side effects of Finerenone may include:

• Hyperkalemia: Elevated potassium levels in the blood are a common side effect of Finerenone. Symptoms of hyperkalemia may include weakness, fatigue, irregular heartbeat, or tingling sensations. Monitoring potassium levels regularly is essential to detect and manage hyperkalemia.
• Hypotension: Finerenone may cause low blood pressure (hypotension), leading to symptoms such as dizziness, lightheadedness, or fainting. Changes in blood pressure should be monitored, especially at the initiation of treatment or with dose adjustments.
• Kidney impairment: Finerenone can affect kidney function, particularly in patients with pre-existing kidney disease. Monitoring kidney function through blood tests is necessary to detect any impairment.
• Increased urination: Some individuals may experience increased frequency of urination while taking Finerenone.
• Dizziness: Dizziness or vertigo may occur as a side effect of Finerenone.
• Fatigue: Feeling tired or experiencing fatigue is a possible side effect of Finerenone.
• Changes in electrolyte levels: Finerenone may cause changes in electrolyte levels, including sodium and magnesium. Regular monitoring of electrolyte levels is important to detect and manage any abnormalities.
• Adrenal insufficiency: In rare cases, Finerenone may lead to adrenal insufficiency, especially when abruptly stopping the medication. Symptoms may include fatigue, weakness, abdominal pain, and weight loss.
• Allergic reactions: Some individuals may experience allergic reactions to Finerenone, characterized by symptoms such as rash, itching, swelling, or difficulty breathing. Seek medical attention immediately if you experience any signs of an allergic reaction.

It’s important to report any side effects experienced while taking Finerenone to your healthcare provider. They can provide guidance on managing side effects and may adjust your treatment if necessary. Additionally, do not discontinue Finerenone without consulting your healthcare provider, as abrupt discontinuation may lead to adverse effects.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage: Store Finerenone tablets at room temperature away from moisture, heat, and light. Keep the medication in its original packaging and out of reach of children and pets.
• Disposal: Dispose of unused or expired Finerenone tablets properly according to local regulations or guidelines. Do not flush them down the toilet or pour them into a drain unless instructed to do so. Consult with your pharmacist or local waste disposal facility for proper disposal methods.

In case of emergency/overdose

In case of emergency or overdose of Finerenone:

• If you suspect an overdose of Finerenone or experience severe symptoms such as difficulty breathing, chest pain, fainting, or seizures, seek emergency medical attention immediately.
• Contact your local poison control center or emergency room for guidance on what to do next.

What other information should I know?

• Regular Follow-up: Attend all scheduled follow-up appointments with your healthcare provider while taking Finerenone. This allows for monitoring of your condition, response to treatment, and any potential side effects.
• Lifestyle Changes: Follow any lifestyle recommendations provided by your healthcare provider, such as dietary modifications, exercise routines, or smoking cessation, to optimize the effectiveness of Finerenone treatment.
• Medical Alert: Inform all healthcare providers involved in your care, including dentists and specialists, that you are taking Finerenone. Wear a medical alert bracelet or carry a medical alert card indicating that you are taking Finerenone in case of emergencies.
• Avoid Alcohol: Limit or avoid alcohol consumption while taking Finerenone, as it may worsen certain side effects such as dizziness or drowsiness.
• Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of Finerenone with your healthcare provider before starting or continuing treatment.
• Medication Review: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as Finerenone may interact with certain medications.

Always follow your healthcare provider’s instructions and guidance when taking Finerenone or any other medication. If you have any questions or concerns, do not hesitate to discuss them with your healthcare provider or pharmacist.