Why is this medication prescribed?

Farxiga is a medication prescribed primarily for the treatment of type 2 diabetes. Its active ingredient is dapagliflozin, which belongs to a class of drugs called SGLT2 inhibitors. Farxiga works by helping the kidneys remove glucose from the bloodstream through urine, thereby lowering blood sugar levels. Additionally, it may also help with weight loss and lowering blood pressure.

How should this medicine be used?

Here’s how Farxiga is typically used:

• Dosage: The usual starting dose for Farxiga is 5 mg taken orally once daily, with or without food. Depending on the individual’s response and tolerability, the dosage may be increased to 10 mg once daily.
• Administration: Farxiga tablets should be swallowed whole with a glass of water. They can be taken at any time of day, with or without food.
• Compliance: It’s important to take Farxiga regularly as prescribed by your healthcare provider to get the maximum benefit from the medication.
• Monitoring: Your healthcare provider may monitor your blood sugar levels regularly while you’re taking Farxiga to ensure it’s effectively managing your diabetes.
• Safety precautions: Before starting Farxiga or any new medication, it’s crucial to inform your healthcare provider about any existing medical conditions you have, other medications you’re taking (including over-the-counter and herbal supplements), and any allergies you may have.
• Lifestyle changes: Along with taking Farxiga, your healthcare provider may recommend lifestyle changes such as diet modification, regular exercise, and weight management to help manage your diabetes effectively.

Always follow your healthcare provider’s instructions regarding the use of Farxiga or any other medication prescribed to you. If you have any questions or concerns about its use, don’t hesitate to discuss them with your healthcare provider.

Other uses for this medicine

Farxiga is primarily indicated for the treatment of type 2 diabetes. However, it may also have potential benefits in other conditions such as heart failure and chronic kidney disease. In some cases, healthcare providers may prescribe Farxiga “off-label” for these conditions, meaning it’s being used for a purpose other than what it was specifically approved for. However, the decision to use Farxiga for these conditions should be made by your doctor based on your individual circumstances.

What special precautions should I follow?

Regarding special precautions for Farxiga, here are some key points to keep in mind:

• Kidney function: Farxiga is primarily eliminated through the kidneys. Therefore, it is important for individuals with impaired kidney function to use Farxiga with caution, as the drug may accumulate in the body and lead to adverse effects. Your healthcare provider may adjust the dosage of Farxiga or monitor your kidney function regularly if you have kidney impairment.
• Dehydration and hypotension: Farxiga can increase the risk of dehydration and low blood pressure, especially in elderly patients or those taking diuretics or other medications that lower blood pressure. It’s essential to stay hydrated and monitor for signs of dehydration, such as increased thirst, dry mouth, weakness, dizziness, or lightheadedness.
• Genital yeast infections: SGLT2 inhibitors like Farxiga may increase the risk of genital yeast infections in both men and women. Patients should be advised to maintain good genital hygiene and seek medical attention if they experience symptoms such as itching, burning, or unusual discharge.
• Hypoglycemia: While Farxiga itself does not typically cause hypoglycemia (low blood sugar), it may increase the risk of hypoglycemia when used in combination with other diabetes medications such as insulin or sulfonylureas. Your healthcare provider may need to adjust the dosage of these medications to reduce the risk of hypoglycemia.
• Ketoacidosis: Farxiga may increase the risk of diabetic ketoacidosis (a serious complication of diabetes characterized by high blood ketone levels) particularly in patients with type 1 diabetes or those with poorly controlled type 2 diabetes. Patients should be advised to seek medical attention immediately if they experience symptoms such as nausea, vomiting, abdominal pain, confusion, or difficulty breathing.
• Pregnancy and breastfeeding: The safety of Farxiga during pregnancy and breastfeeding has not been established. Pregnant or breastfeeding women should consult their healthcare provider before taking Farxiga.

These are general precautions associated with the use of Farxiga. It’s essential to discuss any specific concerns or medical conditions you have with your healthcare provider before starting this medication.

What special dietary instructions should I follow?

Special dietary instructions for Farxiga are generally not required. However, it’s important to maintain a healthy diet as advised by your healthcare provider or a registered dietitian to help manage your diabetes effectively. This may include limiting the intake of refined carbohydrates, sugary foods, and excessive amounts of alcohol, and focusing on consuming a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.

What should I do if I forget a dose?

If you forget to take a dose of Farxiga, take it as soon as you remember, unless it’s almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Farxiga (dapagliflozin) can cause side effects, although not everyone experiences them. Common side effects of Farxiga include:

• Genital yeast infections (such as vaginal yeast infections in women and balanitis in men)
• Urinary tract infections
• Increased urination
• Thirst
• Dehydration
• Hypotension (low blood pressure)
• Dizziness
• Weakness
• Nausea
• Increased cholesterol levels
• Increased levels of blood creatinine (a marker of kidney function)
• Changes in uric acid levels
• Increased risk of fractures, particularly in postmenopausal women

Less common but more serious side effects of Farxiga may include:

• Diabetic ketoacidosis (a serious complication of diabetes characterized by high blood ketone levels)
• Fournier’s gangrene (a rare but serious infection of the genital or perineal area)
• Acute kidney injury
• Serious urinary tract infections
• Hypersensitivity reactions (such as rash, itching, or difficulty breathing)
• Increased risk of amputation, particularly of the toes

It’s important to report any unusual or severe side effects to your healthcare provider promptly. Additionally, if you experience symptoms of a serious allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.

This list may not include all possible side effects of Farxiga. For a comprehensive understanding of potential side effects, consult with your healthcare provider or pharmacist, and carefully read the medication leaflet provided with Farxiga.

What should I know about storage and disposal of this medication?

Storage and disposal:

• Store Farxiga at room temperature away from light and moisture.
• Keep Farxiga in its original packaging or container.
• Do not store Farxiga in the bathroom or kitchen sink.
• Keep Farxiga out of reach of children and pets.
• Do not use Farxiga after the expiration date printed on the packaging. If you have unused or expired Farxiga, dispose of it properly according to local regulations or guidelines.

In case of emergency/overdose

In case of emergency/overdose:

• If you suspect an overdose of Farxiga, seek emergency medical attention or contact your local poison control center immediately.
• Symptoms of an overdose may include excessive urination, dehydration, hypotension (low blood pressure), dizziness, weakness, and increased heart rate.
• Do not induce vomiting unless instructed to do so by a healthcare professional.

What other information should I know?

• Inform all healthcare providers involved in your care that you are taking Farxiga.
• Attend all scheduled appointments with your healthcare provider for monitoring and evaluation of your diabetes and overall health.
• Inform your healthcare provider of any new or worsening symptoms while taking Farxiga.
• Follow your healthcare provider’s instructions regarding diet, exercise, blood sugar monitoring, and other aspects of diabetes management.
• Carry identification or wear a medical alert bracelet indicating that you have diabetes and are taking Farxiga.
• Do not share Farxiga with others, even if they have similar symptoms or conditions.
• Avoid alcohol while taking Farxiga, as it may increase the risk of dehydration and hypoglycemia.
• If you have any questions or concerns about Farxiga or your diabetes treatment plan, consult your healthcare provider or pharmacist for guidance.

By following these guidelines, you can safely store and use Farxiga and know what to do in case of an emergency or overdose. If you have any further questions or need clarification, don’t hesitate to ask your healthcare provider or pharmacist.