WARNING

Fanapt (iloperidone) is an antipsychotic medication used to treat schizophrenia in adults. Like all medications, Fanapt carries certain risks and side effects. Some of the potential risks associated with taking Fanapt include:

• Extrapyramidal symptoms (EPS): These are movement disorders such as tremors, muscle stiffness, and restlessness that can occur as side effects of antipsychotic medications.
• Orthostatic hypotension: Fanapt can cause a drop in blood pressure upon standing, leading to dizziness or fainting.
• Cardiovascular effects: Fanapt may prolong the QT interval, which can increase the risk of abnormal heart rhythms.
• Metabolic changes: Antipsychotic medications like Fanapt can lead to weight gain, high blood sugar, and high cholesterol levels, which may increase the risk of diabetes and cardiovascular disease.
• Neuroleptic Malignant Syndrome (NMS): Although rare, NMS is a potentially life-threatening reaction to antipsychotic medications characterized by fever, muscle rigidity, confusion, and autonomic dysfunction.
• Hyperprolactinemia: Fanapt can increase levels of the hormone prolactin, which may lead to symptoms such as breast enlargement, irregular menstrual periods, and sexual dysfunction.
• Suicidal thoughts and behaviors: Antipsychotic medications, including Fanapt, may increase the risk of suicidal thoughts and behaviors, particularly in young adults.

It’s essential for individuals taking Fanapt to be closely monitored by their healthcare provider for any signs of these potential risks or side effects. It’s also important to discuss any concerns or questions about medication risks with a qualified healthcare professional.

Why is this medication prescribed?

Fanapt (iloperidone) is prescribed primarily for the treatment of schizophrenia in adults. Schizophrenia is a chronic mental disorder characterized by symptoms such as hallucinations, delusions, disorganized thinking, and impaired social functioning. Fanapt helps alleviate these symptoms by affecting certain neurotransmitters in the brain, particularly dopamine and serotonin.

How should this medicine be used?

Here are some key points regarding how Fanapt should be used:

• Dosage: The dosage of Fanapt can vary depending on individual factors such as the severity of symptoms, response to treatment, and any other medications being taken. It’s important to follow the dosage instructions provided by the prescribing healthcare provider.
• Administration: Fanapt is typically taken orally in the form of tablets. It’s usually taken twice daily with food. The tablets should be swallowed whole and not crushed, chewed, or broken.
• Titration: When starting Fanapt treatment, healthcare providers often initiate therapy with a low dose and gradually increase it over time to minimize the risk of side effects.
• Monitoring: Patients taking Fanapt should be regularly monitored by their healthcare provider to evaluate the effectiveness of the medication and to watch for any adverse reactions or side effects.
• Duration of treatment: The duration of treatment with Fanapt can vary depending on the individual’s response to the medication and the course of their illness. Some individuals may require long-term treatment to manage their symptoms effectively.
• Discontinuation: It’s essential not to stop taking Fanapt abruptly without consulting a healthcare professional. Suddenly discontinuing the medication can lead to withdrawal symptoms or a recurrence of symptoms of schizophrenia.
• Adherence: It’s important to take Fanapt exactly as prescribed by the healthcare provider and not to miss any doses. Skipping doses or altering the dosage schedule can affect the effectiveness of the medication.

Overall, the use of Fanapt should be guided by a healthcare professional who can provide personalized recommendations based on the individual’s specific needs and circumstances.

Other uses for this medicine

Some off-label uses of Fanapt may include the treatment of other psychiatric conditions such as bipolar disorder or certain types of mood disorders. However, the decision to prescribe Fanapt for off-label uses should be made by a qualified healthcare provider based on the individual patient’s circumstances and medical history.

What special precautions should I follow?

Regarding special precautions for Fanapt, here are some important considerations:

• Allergies: Patients should inform their healthcare provider of any allergies they have, especially to medications. Some inactive ingredients in Fanapt tablets may cause allergic reactions or other problems.
• Medical history: Before starting Fanapt, patients should disclose their full medical history, including any past or current medical conditions, particularly heart problems, liver disease, kidney disease, seizures, or a history of blood disorders.
• Medication interactions: Patients should inform their healthcare provider about all medications, supplements, or herbal products they are taking, as Fanapt may interact with certain drugs, including other antipsychotic medications, antidepressants, antifungal medications, and certain antibiotics.
• Pregnancy and breastfeeding: It’s important to discuss the risks and benefits of taking Fanapt during pregnancy or while breastfeeding. The medication may pass into breast milk and could potentially harm a nursing infant.
• Driving and operating machinery: Fanapt may cause dizziness or drowsiness, which can impair the ability to drive or operate machinery. Patients should avoid engaging in activities that require alertness until they know how Fanapt affects them.
• Alcohol and other substances: Patients should avoid consuming alcohol or using other substances that may depress the central nervous system while taking Fanapt, as this can increase the risk of side effects such as drowsiness or dizziness.
• Regular monitoring: Patients taking Fanapt should undergo regular monitoring by their healthcare provider to evaluate the effectiveness of the medication and monitor for any potential side effects or adverse reactions.

It’s crucial for patients to follow their healthcare provider’s guidance and instructions regarding the use of Fanapt, including any precautions or special considerations specific to their individual situation.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with taking Fanapt. However, it’s generally advisable to maintain a healthy and balanced diet while taking any medication. If you have any concerns or specific dietary needs, it’s recommended to discuss them with your healthcare provider or a registered dietitian.

What should I do if I forget a dose?

If you forget a dose of Fanapt, take it as soon as you remember, unless it’s close to the time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Fanapt (iloperidone) can cause various side effects, ranging from mild to severe. Not everyone will experience these side effects, and some individuals may experience side effects not listed here. Common side effects of Fanapt include:

• Dizziness: Feeling lightheaded or unsteady.
• Drowsiness: Feeling sleepy or tired.
• Increased heart rate: Palpitations or rapid heartbeat.
• Weight gain: Gaining weight, which can sometimes be significant.
• Orthostatic hypotension: A drop in blood pressure upon standing, leading to dizziness or fainting.
• Constipation: Difficulty passing stools or infrequent bowel movements.
• Dry mouth: Feeling thirsty due to reduced saliva production.
• Nausea and vomiting: Feeling sick to the stomach or vomiting.
• Headache: Pain or discomfort in the head.
• Insomnia: Difficulty falling asleep or staying asleep.
• Akathisia: Restlessness or an inability to sit still.
• Tremor: Involuntary shaking of the hands or other body parts.
• Blurred vision: Difficulty seeing clearly.
• Increased prolactin levels: Leading to symptoms such as breast enlargement, irregular menstrual periods, or sexual dysfunction.

In addition to these common side effects, Fanapt may also cause more severe side effects in some individuals. These can include:

• Neuroleptic Malignant Syndrome (NMS): A rare but potentially life-threatening reaction characterized by fever, muscle rigidity, confusion, and autonomic dysfunction.
• Tardive Dyskinesia: Involuntary movements of the face, tongue, or other body parts, which may be irreversible in some cases.
• QT Prolongation: Abnormal heart rhythm that can lead to fainting, dizziness, or cardiac arrest.
• Hyperglycemia: High blood sugar levels, which can lead to diabetes or exacerbate existing diabetes.
• Hyperlipidemia: Elevated levels of fats in the blood, increasing the risk of cardiovascular disease.

It’s essential to report any concerning or persistent side effects to your healthcare provider promptly. They can assess the severity of the side effects and determine the appropriate course of action, which may include adjusting the dosage, switching medications, or providing supportive care.

What should I know about storage and disposal of this medication?

Storage and disposal of Fanapt:

Storage:

• Store Fanapt tablets at room temperature, away from moisture and heat.
• Keep the medication in its original packaging or container to protect it from light.
• Ensure that Fanapt is stored in a secure location out of reach of children and pets.

Disposal:

• Dispose of any unused or expired Fanapt tablets properly.
• Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
• Consult with your pharmacist or local waste disposal facility for guidance on how to dispose of Fanapt safely.

In case of emergency/overdose

In case of emergency or overdose of Fanapt, take the following steps:

• Contact emergency medical services immediately by dialing the emergency number in your area (e.g., 911 in the United States).
• Provide as much information as possible about the overdose, including the amount of medication taken and any symptoms experienced.
• If possible, bring the medication packaging or container to the healthcare facility to assist medical professionals in providing appropriate treatment.

What other information should I know?

• Fanapt may cause drowsiness or dizziness. Avoid activities that require mental alertness, such as driving or operating machinery, until you know how Fanapt affects you.
• Inform your healthcare provider about all medications, supplements, or herbal products you are taking, as they may interact with Fanapt.
• Attend all scheduled medical appointments for monitoring and follow-up while taking Fanapt.
• Keep a list of all medications you are taking, including prescription and over-the-counter medications, and share it with your healthcare provider.
• Do not stop taking Fanapt abruptly without consulting your healthcare provider, as this can lead to withdrawal symptoms or a recurrence of symptoms.
• Follow your healthcare provider’s instructions carefully regarding dosage and administration of Fanapt.
• If you have any questions or concerns about Fanapt or its use, consult your healthcare provider or pharmacist for guidance.