Why is this medication prescribed?

Ertugliflozin is prescribed primarily for the management of type 2 diabetes mellitus in adults. Type 2 diabetes is a condition characterized by elevated blood sugar levels due to either insufficient insulin production by the body or ineffective utilization of insulin.

Ertugliflozin belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors. These drugs work by blocking the reabsorption of glucose by the kidneys, leading to the excretion of excess glucose in the urine and subsequently lowering blood sugar levels. By helping to control blood sugar levels, Ertugliflozin can reduce the risk of diabetes-related complications such as kidney disease, heart disease, stroke, nerve damage, and eye problems.

It’s important to note that Ertugliflozin is typically prescribed as part of a comprehensive treatment plan for type 2 diabetes, which may also include lifestyle modifications such as diet and exercise, as well as other antidiabetic medications. The decision to prescribe Ertugliflozin and the appropriate dosage will depend on individual factors such as the patient’s overall health, medical history, and response to treatment.

How should this medicine be used?

Ertugliflozin is usually taken orally once daily, with or without food. The dosage typically depends on the individual’s medical condition and response to treatment. It’s important to follow the dosage instructions provided by your healthcare provider.

Here are some general guidelines on how Ertugliflozin should be used:

• Follow the prescribed dosage: Take Ertugliflozin exactly as directed by your healthcare provider. Do not take more or less of it or take it more frequently than prescribed.
• Take it consistently: Try to take Ertugliflozin at the same time each day to maintain a consistent level of the medication in your bloodstream.
• Swallow the tablet whole: Do not crush, chew, or break the tablets. Swallow them whole with a glass of water.
• Continue other treatments: Ertugliflozin is usually used as part of a comprehensive treatment plan for type 2 diabetes, which may include other medications, lifestyle changes (such as diet and exercise), and regular monitoring of blood sugar levels. Continue to follow all other treatment recommendations provided by your healthcare provider.
• Monitor blood sugar levels: Regularly monitor your blood sugar levels as directed by your healthcare provider to ensure that Ertugliflozin is effectively controlling your diabetes.
• Attend follow-up appointments: Attend all scheduled follow-up appointments with your healthcare provider to monitor your response to treatment and make any necessary adjustments to your medication regimen.
• Inform your healthcare provider: Inform your healthcare provider about any other medications, supplements, or medical conditions you have, as they may interact with Ertugliflozin or affect its effectiveness.

It’s important to consult your healthcare provider for personalized advice on how to use Ertugliflozin properly, as individual circumstances and medical history can affect its use and dosage.

Other uses for this medicine

Ertugliflozin is primarily indicated for the treatment of type 2 diabetes mellitus in adults. However, it’s essential to note that healthcare providers may sometimes prescribe medications off-label for conditions other than those officially approved by regulatory authorities. At this time, there aren’t any widely recognized alternative uses for Ertugliflozin beyond its approved indication for type 2 diabetes.

What special precautions should I follow?

Regarding special precautions for using Ertugliflozin, here are some important considerations:

• Kidney function: Ertugliflozin works by increasing the excretion of glucose through the kidneys. It’s essential for healthcare providers to assess kidney function before starting treatment with Ertugliflozin and to monitor kidney function periodically during treatment. This is because Ertugliflozin may not be suitable for individuals with severe kidney impairment or those undergoing dialysis.
• Dehydration and low blood pressure: Ertugliflozin can increase the risk of dehydration and low blood pressure, particularly in older adults or individuals taking diuretic medications. Patients should be advised to stay well-hydrated and to report any symptoms of dehydration or low blood pressure, such as dizziness, fainting, or lightheadedness, to their healthcare provider.
• Genital infections: Ertugliflozin may increase the risk of genital infections, such as yeast infections in women and balanitis in men. Patients should be educated about the signs and symptoms of genital infections and instructed to seek medical attention if they occur.
• Hypoglycemia: While Ertugliflozin itself does not typically cause hypoglycemia (low blood sugar), it may increase the risk of hypoglycemia when used in combination with other antidiabetic medications, such as insulin or sulfonylureas. Patients should be counseled on the signs and symptoms of hypoglycemia and how to manage it appropriately.
• Ketoacidosis: Ertugliflozin has been associated with an increased risk of diabetic ketoacidosis (a serious complication of diabetes characterized by high levels of ketones in the blood). Patients should be advised to seek medical attention immediately if they experience symptoms of ketoacidosis, such as nausea, vomiting, abdominal pain, difficulty breathing, confusion, or unusual fatigue.
• Surgery and other medical procedures: Patients should inform their healthcare providers that they are taking Ertugliflozin before undergoing any surgical or medical procedures, as temporary discontinuation of the medication may be necessary.
• Pregnancy and breastfeeding: The safety of Ertugliflozin during pregnancy and breastfeeding has not been established. Pregnant or breastfeeding individuals should consult their healthcare provider before taking Ertugliflozin.

It’s crucial for patients to discuss any concerns or questions about Ertugliflozin with their healthcare provider, as they can provide personalized guidance based on individual medical history and circumstances.

What special dietary instructions should I follow?

Regarding special dietary instructions for Ertugliflozin, there are no specific dietary restrictions associated with its use. However, maintaining a healthy diet as recommended by your healthcare provider is important for managing diabetes effectively. This typically includes consuming a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats, while limiting intake of refined sugars and processed foods.

What should I do if I forget a dose?

If you forget to take a dose of Ertugliflozin, take it as soon as you remember, unless it is close to the time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for advice.

What side effects can this medication cause?

Ertugliflozin, like any medication, can cause side effects. Not everyone will experience these side effects, and their severity can vary from person to person. Common side effects of Ertugliflozin may include:

• Genital yeast infections (in women) or balanitis (in men)
• Urinary tract infections
• Increased urination
• Increased thirst
• Hypoglycemia (low blood sugar) when used in combination with other antidiabetic medications
• Dehydration
• Dizziness
• Fatigue
• Nausea
• Constipation
• Increased cholesterol levels
• Increased levels of ketones in the blood (ketoacidosis)

It’s important to note that this is not a complete list of all possible side effects of Ertugliflozin. Some individuals may experience other side effects not listed here. Additionally, serious side effects such as severe allergic reactions or kidney problems may occur but are less common.

Patients should report any unusual or bothersome side effects to their healthcare provider. It’s essential to seek medical attention immediately if you experience symptoms of a serious allergic reaction, such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing.

As always, it’s crucial to discuss any concerns or questions about side effects with your healthcare provider, who can provide personalized advice and guidance based on your individual medical history and circumstances.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage: Store Ertugliflozin tablets at room temperature away from light and moisture. Keep the medication in its original packaging and out of reach of children and pets.
• Disposal: Dispose of unused or expired Ertugliflozin tablets properly according to local regulations or guidelines. Do not flush medications down the toilet or pour them down the drain unless instructed to do so. Consult with your pharmacist or local waste disposal authority for the proper disposal method.

In case of emergency/overdose

In case of an overdose or emergency, contact your local poison control center or emergency room immediately. Symptoms of overdose may include dehydration, excessive urination, dizziness, fainting, or confusion. If possible, provide the medical personnel with information about the amount of Ertugliflozin ingested.

What other information should I know?

• Follow all instructions provided by your healthcare provider and pharmacist regarding the use of Ertugliflozin.
• Inform your healthcare provider about all medications, supplements, and herbal products you are currently taking, as they may interact with Ertugliflozin.
• Attend all scheduled follow-up appointments with your healthcare provider for monitoring and adjustments to your treatment regimen.
• Maintain a healthy lifestyle, including a balanced diet, regular exercise, and appropriate weight management, as recommended by your healthcare provider.
• Keep track of your blood sugar levels as directed by your healthcare provider and report any significant changes or concerns promptly.

It’s essential to have open communication with your healthcare provider and pharmacist regarding any questions or concerns you may have about Ertugliflozin. They can provide personalized advice and guidance based on your individual medical needs and circumstances.