Why is this medication prescribed?

Epanova is a prescription medication used to lower triglyceride levels in adults with severe hypertriglyceridemia (very high levels of triglycerides in the blood). Triglycerides are a type of fat found in the blood and high levels can increase the risk of cardiovascular diseases.

Epanova contains omega-3 fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are known to help reduce triglyceride levels.

How should this medicine be used?

Here’s how Epanova is typically used:

• Dosage: The dosage of Epanova can vary depending on individual patient factors and the severity of hypertriglyceridemia. It is usually prescribed by a healthcare provider who will determine the appropriate dosage for each patient.
• Administration: Epanova is taken orally in the form of soft gel capsules.
• Timing: It is usually recommended to take Epanova with meals to maximize absorption and minimize gastrointestinal side effects.
• Follow healthcare provider’s instructions: Patients should follow the dosage and administration instructions provided by their healthcare provider carefully. It’s essential not to exceed the prescribed dose unless directed by a healthcare professional.
• Regular monitoring: Patients taking Epanova may require regular monitoring of their triglyceride levels to assess the effectiveness of the medication and make any necessary adjustments to the dosage.
• Lifestyle modifications: Along with medication, lifestyle changes such as adopting a healthy diet, regular exercise, and avoiding alcohol and smoking may also be recommended to help manage triglyceride levels effectively.

It’s important for patients to discuss any questions or concerns about Epanova with their healthcare provider, and to report any side effects or unusual symptoms experienced while taking the medication.

Other uses for this medicine

While Epanova is primarily prescribed for lowering triglyceride levels in adults with severe hypertriglyceridemia, there may be other potential uses for this medication as well. However, any alternative uses would be determined by healthcare providers based on individual patient needs and conditions, and they would be prescribed off-label.

What special precautions should I follow?

Special precautions to follow when taking Epanova include:

• Allergy: Inform your healthcare provider if you are allergic to fish or shellfish, as Epanova contains omega-3 fatty acids derived from fish oil. Allergic reactions to fish oil-based supplements are rare but possible.
• Pregnancy and breastfeeding: If you are pregnant or breastfeeding, consult with your healthcare provider before taking Epanova. Omega-3 fatty acids are generally considered safe during pregnancy and breastfeeding when obtained from dietary sources like fish, but it’s important to discuss potential risks and benefits with your healthcare provider.
• Medical history: Inform your healthcare provider about your medical history, especially if you have liver disease, pancreatitis, diabetes, or any other medical conditions. These conditions may require special monitoring or adjustments in dosage while taking Epanova.
• Medication interactions: Inform your healthcare provider about all the medications, vitamins, and supplements you are currently taking, as they may interact with Epanova. This includes blood thinners (anticoagulants) and other medications that affect bleeding, such as aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs).
• Side effects: Be aware of potential side effects of Epanova, including gastrointestinal symptoms such as diarrhea, nausea, or indigestion. If you experience any unusual or severe side effects, contact your healthcare provider immediately.
• Routine check-ups: Your healthcare provider may recommend regular check-ups and monitoring of your triglyceride levels while taking Epanova to assess its effectiveness and adjust the dosage if necessary.
• Storage: Store Epanova capsules at room temperature away from light and moisture. Keep them out of reach of children and pets.

Always follow your healthcare provider’s instructions and guidance when taking Epanova or any other medication. If you have any questions or concerns about the medication, don’t hesitate to discuss them with your healthcare provider.

What special dietary instructions should I follow?

• Follow a healthy diet as recommended by your healthcare provider, which may include reducing intake of saturated fats, trans fats, cholesterol, and refined carbohydrates.
• Include foods rich in omega-3 fatty acids, such as fatty fish (e.g., salmon, mackerel, sardines), flaxseeds, chia seeds, walnuts, and soybeans, as part of your diet.

What should I do if I forget a dose?

• If you miss a dose of Epanova, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for a missed one.
• If you are unsure about what to do, or if you miss multiple doses, consult your healthcare provider for guidance.

What side effects can this medication cause?

Epanova, like any medication, can cause side effects in some people. Common side effects associated with Epanova may include:

• Gastrointestinal Issues: These can include symptoms such as diarrhea, nausea, vomiting, and indigestion.
• Allergic Reactions: While rare, some individuals may experience allergic reactions to Epanova. Symptoms of an allergic reaction may include rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing.
• Bleeding: Omega-3 fatty acids, which are the active ingredients in Epanova, may have mild anticoagulant effects. While this is generally beneficial for cardiovascular health, it can increase the risk of bleeding in some individuals, particularly if they are also taking blood-thinning medications like warfarin.
• Liver Problems: There have been reports of liver problems, including increased liver enzymes, with the use of omega-3 fatty acid supplements. These symptoms may include yellowing of the skin or eyes (jaundice), dark urine, abdominal pain, or unusual tiredness.
• Other Potential Side Effects: Some individuals may experience other side effects not listed here. If you experience any new or unusual symptoms while taking Epanova, it’s important to report them to your healthcare provider.

It’s essential to note that not everyone will experience these side effects, and many people tolerate Epanova well. Additionally, the benefits of taking Epanova in reducing triglyceride levels and lowering the risk of cardiovascular events generally outweigh the potential risks of side effects for most individuals.

If you experience severe or persistent side effects while taking Epanova, or if you have any concerns about the medication, be sure to contact your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

Storage and Disposal:

• Storage:
  • Store Epanova capsules at room temperature (between 68-77°F or 20-25°C).
  • Keep the medication in its original container, tightly closed, and away from moisture and light.
  • Do not store Epanova in the bathroom or near the kitchen sink, as moisture and humidity can degrade the medication.
  • Keep Epanova out of reach of children and pets.
• Disposal:
  • Dispose of any unused or expired Epanova capsules properly according to local regulations or guidelines.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Instead, consult your pharmacist or local waste disposal company for proper disposal instructions.

In case of emergency/overdose

• In case of an overdose or emergency, such as accidentally taking too much Epanova, contact your local poison control center (in the United States, call 1-800-222-1222) or seek emergency medical attention immediately.
• Be prepared to provide information about the amount of medication ingested, the time it was taken, and any symptoms experienced.

What other information should I know?

• Keep all appointments with your healthcare provider for monitoring of your condition and response to treatment with Epanova.
• Inform any other healthcare providers (such as dentists or specialists) that you are taking Epanova before undergoing any medical procedures or surgeries.
• Follow your healthcare provider’s dietary and lifestyle recommendations, including maintaining a healthy diet, regular exercise, and avoiding smoking and excessive alcohol consumption, to help manage your condition effectively.
• Keep a list of all medications, vitamins, and supplements you are taking and share it with your healthcare provider to prevent potential interactions with Epanova.
• Report any new or unusual symptoms, side effects, or changes in your health to your healthcare provider promptly.

By following these storage, disposal, emergency procedures, and other important guidelines, you can safely and effectively manage your treatment with Epanova. If you have any questions or concerns, don’t hesitate to consult your healthcare provider or pharmacist for further assistance.