WARNING

Taking Entuss, like any medication, carries certain risks and potential side effects. Here’s a brief overview of some of the risks associated with Entuss:

• Respiratory Depression: Entuss contains hydrocodone, which is an opioid medication. Opioids can suppress breathing, particularly in high doses or when combined with other central nervous system depressants like alcohol or certain medications. Respiratory depression can be life-threatening and requires immediate medical attention.
• Addiction and Dependence: Hydrocodone, being an opioid, has the potential for addiction and dependence, especially with long-term use or misuse. Dependence can lead to withdrawal symptoms if the medication is abruptly stopped.
• Sedation and Drowsiness: Both guaifenesin and hydrocodone can cause drowsiness and sedation. This effect can impair your ability to drive or operate machinery safely. It’s important to avoid activities requiring mental alertness until you know how Entuss affects you.
• Constipation: Opioids like hydrocodone commonly cause constipation, which can be bothersome and may require additional treatment to manage effectively.
• Nausea and Vomiting: Some individuals may experience nausea or vomiting as side effects of Entuss.
• Allergic Reactions: While rare, allergic reactions to any component of Entuss can occur. Seek medical attention immediately if you experience symptoms such as rash, itching, swelling, severe dizziness, or trouble breathing.
• Drug Interactions: Entuss can interact with other medications, including certain antidepressants, antihistamines, sedatives, and muscle relaxants, potentially leading to adverse effects or reduced efficacy of either medication.
• Overdose: Taking too much Entuss, whether accidentally or intentionally, can lead to overdose, which can be fatal. Symptoms of overdose may include extreme drowsiness, confusion, shallow breathing, pinpoint pupils, slow heartbeat, or loss of consciousness.

It’s crucial to use Entuss only as prescribed by your healthcare provider and to communicate any concerns or side effects to them promptly. Do not exceed the recommended dosage or duration of treatment without medical guidance. If you have a history of substance abuse or certain medical conditions, your doctor may need to adjust your treatment plan or monitor you more closely while taking Entuss.

Why is this medication prescribed?

Entuss is a prescription medication that contains two active ingredients: guaifenesin and hydrocodone. It is typically prescribed for the relief of cough associated with conditions such as the common cold, bronchitis, or other respiratory tract infections where coughing is a predominant symptom.

• Guaifenesin: Guaifenesin is an expectorant that helps to thin and loosen mucus in the airways, making it easier to cough up and clear the air passages.
• Hydrocodone: Hydrocodone is an opioid cough suppressant that works by acting on the brain to reduce the urge to cough.

How should this medicine be used?

When using Entuss, it’s crucial to adhere to your healthcare provider’s instructions precisely. Here are some general guidelines for its usage:

• Dosage: Take Entuss exactly as prescribed by your doctor. The dosage will depend on factors such as your medical condition, age, weight, and response to treatment. Do not adjust the dosage without consulting your doctor.
• Administration: Entuss is typically taken orally, with or without food. Swallow the tablets whole with a full glass of water. Do not crush, chew, or break the tablets, as this can alter their effectiveness and increase the risk of side effects.
• Liquid Formulation: If you’re using a liquid formulation of Entuss, use a measuring device to ensure accurate dosage. Do not use a household spoon, as it may not provide the correct measurement.
• Frequency: Take Entuss as directed by your doctor. Do not take it more frequently than prescribed, as this can increase the risk of adverse effects.
• Duration: Follow the prescribed duration of treatment. Do not continue taking Entuss longer than recommended unless instructed by your doctor.
• Missed Dose: If you miss a dose of Entuss, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to compensate for a missed one.
• Discontinuation: Do not stop taking Entuss suddenly without consulting your doctor, as this can lead to withdrawal symptoms, especially if you’ve been using it for an extended period or in high doses. Your doctor may need to gradually taper the dosage to minimize withdrawal effects.

It’s essential to use Entuss responsibly and to be aware of its potential side effects and interactions with other medications. If you have any questions or concerns about using Entuss, consult your doctor or pharmacist for guidance.

Other uses for this medicine

Off-label uses of Entuss might include the management of cough associated with conditions such as chronic obstructive pulmonary disease (COPD), asthma exacerbations, or other respiratory conditions where coughing is a significant symptom. However, it’s essential to note that using medications off-label should only be done under the guidance and supervision of a healthcare professional.

What special precautions should I follow?

As for special precautions to follow when taking Entuss, consider the following:

• Medical History: Before taking Entuss, inform your doctor about your complete medical history, especially if you have a history of respiratory disorders, liver or kidney disease, substance abuse, mental health disorders, or if you’re pregnant or breastfeeding.
• Allergies: Inform your doctor about any allergies you have, particularly to opioids, guaifenesin, or any other medications.
• Medication Interactions: Provide a list of all medications, supplements, and herbal products you’re currently taking to your doctor or pharmacist to check for potential interactions with Entuss.
• Driving and Operating Machinery: Entuss may cause drowsiness or dizziness. Avoid driving, operating heavy machinery, or engaging in activities requiring mental alertness until you know how Entuss affects you.
• Alcohol: Avoid consuming alcohol while taking Entuss, as it can increase the risk of drowsiness, respiratory depression, and other side effects.
• Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, discuss the risks and benefits of taking Entuss with your doctor. Hydrocodone, an opioid in Entuss, can pass into breast milk and may harm a nursing infant.
• Dosage and Duration: Take Entuss exactly as prescribed by your doctor. Do not exceed the recommended dosage or duration of treatment without medical supervision.
• Storage: Store Entuss at room temperature away from moisture and heat. Keep it out of reach of children and pets.
• Disposal: Dispose of any unused or expired Entuss tablets or liquid according to local regulations or guidelines. Do not flush them down the toilet or pour them into a drain unless instructed to do so.

Following these precautions can help ensure the safe and effective use of Entuss. If you have any questions or concerns, consult your healthcare provider for guidance.

What special dietary instructions should I follow?

Special dietary instructions for Entuss are generally not required. However, it’s essential to stay adequately hydrated while taking the medication to help loosen mucus and support overall respiratory health. Drinking plenty of fluids, such as water, can also help prevent constipation, a common side effect of opioids like hydrocodone.

What should I do if I forget a dose?

If you forget a dose of Entuss, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one. If you’re unsure about what to do, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Entuss (guaifenesin and hydrocodone) can cause several side effects, ranging from mild to severe. It’s essential to be aware of these potential side effects and to promptly report any concerning symptoms to your healthcare provider. Common side effects of Entuss may include:

• Drowsiness
• Dizziness
• Nausea
• Vomiting
• Constipation
• Headache
• Dry mouth
• Blurred vision
• Difficulty urinating
• Rash or itching

Less common but more severe side effects of Entuss may include:

• Respiratory depression (slow or shallow breathing)
• Confusion or disorientation
• Hallucinations
• Severe allergic reactions, such as rash, itching, swelling, severe dizziness, or trouble breathing
• Adverse effects on the liver or kidneys
• Mood changes, including depression or agitation
• Increased heart rate or irregular heartbeat
• Seizures
• Loss of consciousness

If you experience any severe or concerning side effects while taking Entuss, seek immediate medical attention. It’s also essential to inform your healthcare provider about any side effects you experience, even if they seem mild, as they may indicate the need for a dosage adjustment or a change in medication.

Additionally, because Entuss contains hydrocodone, an opioid medication, it carries a risk of addiction, dependence, and overdose. Misuse or abuse of Entuss can lead to serious health consequences, including respiratory depression, coma, and death. It’s crucial to use Entuss only as prescribed by your healthcare provider and to follow all instructions carefully.

What should I know about storage and disposal of this medication?

Storage and disposal of Entuss:

• Storage: Store Entuss at room temperature away from moisture and heat. Keep it in a secure location out of reach of children and pets. Avoid storing it in the bathroom or near the kitchen sink, where it might be exposed to moisture. Follow any specific storage instructions provided by your pharmacist or healthcare provider.
• Disposal: Dispose of any unused or expired Entuss tablets or liquid according to local regulations or guidelines. Do not flush them down the toilet or pour them into a drain unless instructed to do so. Instead, consult your pharmacist or local waste disposal facility for guidance on the proper disposal of medication.

In case of emergency/overdose

In case of an overdose or emergency situation related to Entuss, such as severe respiratory depression, loss of consciousness, or other serious symptoms, seek immediate medical attention by calling your local emergency services or going to the nearest emergency room. Be prepared to provide information about the medication ingested, including the dosage and time of ingestion.

What other information should I know?

• Avoid consuming alcohol while taking Entuss, as it can increase the risk of side effects such as drowsiness and respiratory depression.
• Do not drive or operate heavy machinery until you know how Entuss affects you, as it may cause drowsiness, dizziness, or impair your ability to concentrate.
• Inform your healthcare provider about all medications, supplements, and herbal products you are currently taking to avoid potential interactions with Entuss.
• Keep all appointments with your doctor and laboratory while taking Entuss to monitor your progress and check for any side effects or complications.
• Do not share Entuss with others, especially those with a history of substance abuse or addiction, as it contains hydrocodone, an opioid medication that can be habit-forming.
• If you have any questions or concerns about Entuss or its use, consult your healthcare provider or pharmacist for guidance and clarification.

By following these guidelines and staying informed about Entuss and its proper use, storage, and disposal, you can help ensure its safe and effective use while minimizing the risk of adverse effects and complications.